NRSG 2350 CORE EXAM TEST 2026 QUESTIONS AND
SOLUTIONS GRADED A+
✔✔Contraindications of Flouroquinolones - ✔✔Previous allergic
reaction/hypersensitivity to the drugs
Certain disorders that predispose to arrhythmias (eg, QT-interval prolongation,
uncorrected hypokalemia or hypomagnesemia, significant bradycardia)
Children less than 18
✔✔Side effects of fluoroquinolones - ✔✔GI Upset (nausea vomiting diarrhea and
abdomen pain), Dizziness, photosensitivity,
Risk for tendonitis & tendon rupture
(think: Your tendon is on the FLOOR and can rupture from FLOORoquinolones)
✔✔Uses of Flouroquinolones - ✔✔indicated for treatment of:
several bacterial infections, including bacterial bronchitis, pneumonia, sinusitis,
urinary tract infections, septicemia
intraabdominal infections,
joint and bone infections,
soft tissue and skin infections, typhoid fever, anthrax, bacterial gastroenteritis
✔✔Nursing Considerations of Flouroquinolones - ✔✔Photosensitivity- use sunblock and
avoid sun!
Take on an empty stomach with a full glass of water!
✔✔Prototype of Flouroquinolones - ✔✔nalidixic acid
✔✔Penicillin - ✔✔Penicillins are a group of broad spectrum bactericidal beta-lactam
antibiotics that inhibit bacterial cell wall synthesis. They were the first drugs of this type
that doctors used.
✔✔How do penicillin work? (MOA) - ✔✔by destroying bacterial cell wall integrity which
leads to lysis
✔✔Penicillin examples - ✔✔penicillin, amoxicillin, ampicillin
Suffix: -cillin
✔✔Contraindications of Penicillin - ✔✔Patients with history of hypersensitivity to
penicillin or the cephalosporins; renal disease, asthma, bleeding disorders, GI disease
✔✔Side effects of penicillin - ✔✔GI Upset: diarrhea, nausea, vomiting,
IM/IV: pain at injection site
PO: glossitis
, ✔✔Uses of Penicillin - ✔✔to treat respiratory tract infections (pneumonia), UTIs, STIs
(syphilis), septicemia, meningitis, intra-abdominal infections
-commonly used as prophylaxis (prevention) against secondary infections
✔✔Nursing Considerations of Penicillin - ✔✔Pregnancy and Breast-feeding safe.
Renders oral contraceptives ineffective. Take with food to avoid GI upset.
✔✔Prototypes of Penicillin - ✔✔Penicillin g, nafacillin, amoxicillin, ticarcillin
✔✔Sulfonamides - ✔✔a group of man-made (synthetic) medicines that contain the
sulfonamide chemical group. also be called sulfa drugs.
✔✔How do sulfonamides work? - ✔✔interferes with the synthesis of folic acid which
inhibits the metabolism (Bacteriostatis). They slow the growth of the bacteria long
enough for the body's own immune response to kick in (WBCs).
✔✔Examples of sulfonamides - ✔✔Gantrisin (sulfisoxazole)
Bactrim or Septra (trimethoprim and sulfamethoxazole)
Sulfadiazine.
Azulfidine (sulfasalazine)
Prefix: SULFA-
✔✔Contraindications of sulfonamides - ✔✔hypersensitive to sulfa drugs, allergy to
sulfonylureas (oral antibiotics), pregnancy grade D
✔✔Uses of Sulfonamides - ✔✔to treat UTI (E.coli), acute otitis media, bronchitis, and
strept pneumonia, Topical for burn wounds
✔✔Side effects of sulfonamides - ✔✔GI Upset! : Nausea, vomiting, Diarrhea
Rash, dermatitis
Photosensitivity
Hepatic toxicity
Renal damage with crystalluria
Hypersensitivity re-actions (can be fatal)
Hematologic Changes:
WBCs, platelets, RBCs = go down
✔✔Nursing Considerations of Sulfonamides - ✔✔increase fluids because sulfas dry out
the body!
sunblock and avoid sun!
Take folic acid daily
SOLUTIONS GRADED A+
✔✔Contraindications of Flouroquinolones - ✔✔Previous allergic
reaction/hypersensitivity to the drugs
Certain disorders that predispose to arrhythmias (eg, QT-interval prolongation,
uncorrected hypokalemia or hypomagnesemia, significant bradycardia)
Children less than 18
✔✔Side effects of fluoroquinolones - ✔✔GI Upset (nausea vomiting diarrhea and
abdomen pain), Dizziness, photosensitivity,
Risk for tendonitis & tendon rupture
(think: Your tendon is on the FLOOR and can rupture from FLOORoquinolones)
✔✔Uses of Flouroquinolones - ✔✔indicated for treatment of:
several bacterial infections, including bacterial bronchitis, pneumonia, sinusitis,
urinary tract infections, septicemia
intraabdominal infections,
joint and bone infections,
soft tissue and skin infections, typhoid fever, anthrax, bacterial gastroenteritis
✔✔Nursing Considerations of Flouroquinolones - ✔✔Photosensitivity- use sunblock and
avoid sun!
Take on an empty stomach with a full glass of water!
✔✔Prototype of Flouroquinolones - ✔✔nalidixic acid
✔✔Penicillin - ✔✔Penicillins are a group of broad spectrum bactericidal beta-lactam
antibiotics that inhibit bacterial cell wall synthesis. They were the first drugs of this type
that doctors used.
✔✔How do penicillin work? (MOA) - ✔✔by destroying bacterial cell wall integrity which
leads to lysis
✔✔Penicillin examples - ✔✔penicillin, amoxicillin, ampicillin
Suffix: -cillin
✔✔Contraindications of Penicillin - ✔✔Patients with history of hypersensitivity to
penicillin or the cephalosporins; renal disease, asthma, bleeding disorders, GI disease
✔✔Side effects of penicillin - ✔✔GI Upset: diarrhea, nausea, vomiting,
IM/IV: pain at injection site
PO: glossitis
, ✔✔Uses of Penicillin - ✔✔to treat respiratory tract infections (pneumonia), UTIs, STIs
(syphilis), septicemia, meningitis, intra-abdominal infections
-commonly used as prophylaxis (prevention) against secondary infections
✔✔Nursing Considerations of Penicillin - ✔✔Pregnancy and Breast-feeding safe.
Renders oral contraceptives ineffective. Take with food to avoid GI upset.
✔✔Prototypes of Penicillin - ✔✔Penicillin g, nafacillin, amoxicillin, ticarcillin
✔✔Sulfonamides - ✔✔a group of man-made (synthetic) medicines that contain the
sulfonamide chemical group. also be called sulfa drugs.
✔✔How do sulfonamides work? - ✔✔interferes with the synthesis of folic acid which
inhibits the metabolism (Bacteriostatis). They slow the growth of the bacteria long
enough for the body's own immune response to kick in (WBCs).
✔✔Examples of sulfonamides - ✔✔Gantrisin (sulfisoxazole)
Bactrim or Septra (trimethoprim and sulfamethoxazole)
Sulfadiazine.
Azulfidine (sulfasalazine)
Prefix: SULFA-
✔✔Contraindications of sulfonamides - ✔✔hypersensitive to sulfa drugs, allergy to
sulfonylureas (oral antibiotics), pregnancy grade D
✔✔Uses of Sulfonamides - ✔✔to treat UTI (E.coli), acute otitis media, bronchitis, and
strept pneumonia, Topical for burn wounds
✔✔Side effects of sulfonamides - ✔✔GI Upset! : Nausea, vomiting, Diarrhea
Rash, dermatitis
Photosensitivity
Hepatic toxicity
Renal damage with crystalluria
Hypersensitivity re-actions (can be fatal)
Hematologic Changes:
WBCs, platelets, RBCs = go down
✔✔Nursing Considerations of Sulfonamides - ✔✔increase fluids because sulfas dry out
the body!
sunblock and avoid sun!
Take folic acid daily
