Psychopharmacologic Approaches to Treatment of
Psychopathology latest update
classic synaptic neurotransmission - ---✔✔✔ANSWER----stimulation of a
presynaptic neuron (e.g., by neurotransmitters, light, drugs, hormones, nerve
impulses) causes electrical impulses to be sent to its axon terminal. These
electrical impulses are then converted into chemical messengers and released to
stimulate the receptors of a postsynaptic neuron.
The synaptic cleft - ---✔✔✔ANSWER----is the gap between the
presynaptic neuron and the postsynaptic neuron; it contains proteins and
scaffolding and molecular forms of "synaptic glue" to reinforce the connection
between the neurons. Receptors are present on both sides of this cleft and are
key elements of chemical neurotransmission.
the soma - ---✔✔✔ANSWER----is the command center of the nerve and
contains the nucleus of the cell
axon - ---✔✔✔ANSWER----Neurons send information via an ____ that
forms presynaptic terminals as the ____ passes by (en passant) or as the ____
ends
, axodendritic - ---✔✔✔ANSWER----synaptic connections between the axon
and dendrites of two neurons
axosomatic - ---✔✔✔ANSWER----synaptic connections between the axon
and the soma
axoaxonic - ---✔✔✔ANSWER----synaptic connections between axons of
the two neurons
The chemical basis of neurotransmission - ---✔✔✔ANSWER----is how
chemical signals are coded, decoded, transduced, and sent along the way.
The anatomical basis of neurotransmission - ---✔✔✔ANSWER----is
neurons and the connections between them, called synapses, sometimes also
called the anatomically addressed nervous system, a complex of "hard-wired"
synaptic connections between neurons, not unlike millions of telephone wires
within thousands upon thousands of cables
The cytochrome P450 (CYP) enzyme system - ---✔✔✔ANSWER----
mediates how the body metabolizes many drugs, including antipsychotics.
The CYP enzyme - ---✔✔✔ANSWER----in the gut wall or liver converts the
drug into a biotransformed product in the bloodstream. After passing through the
gut wall and liver, the drug will exist partly as unchanged drug and partly as
biotransformed drug.