EXAM WITH 100% CORRECT
ANSWERS 2026
How do antigout medications work? correct answers >> by
inhibiting the infiltration and phagocytosis of leukocytes, thus
decreasing the breakdown of uric acid to urate crystals.
Deposition of urate crystals causes correct answers >> pain
and inflammation
What is Colchicine correct answers >> anti-gout medication
how does Colchicine work? correct answers >> Works by
inhibiting inflammation, reducing pain and swelling
common side effects of Colchicine correct answers >> GI
problems (diarrhea) use with caution in elderly
Also can cause blood dyscrasias & abdominal pain
patient education with Colchicine correct answers >> Can be
given with food & milk to decrease GI issues
Avoid beer, ale, & wine: may cause gout attack
Increase fluid intake: increases excretion of uric acid
Avoid smoked meats & high-protein diets
,Low dose of Colchicine correct answers >> Low dose
colchicine is 1.2mg followed by 0.6mg one hour later or 1.8
milligrams total
High dose of Colchicine correct answers >> high dose
colchicine is 1.2mg followed by 0.6mg every four to six hours; or
4.8mg total.
Difference between high dose and low dose Colchicine correct
answers >> The difference between the two is low dose is as
effective as high dose with a lower side effect profile.
Lab values to monitor with Colchicine correct answers >>
Check renal function test, BUN, Creatine
Patient education with Colchicine correct answers >> Almost
always causes some degree of diarrhea, make sure patients are
aware of this side effect
Patient education with Febuxostat (Uloric) correct answers >>
Gout may worsen with therapy initially
Dietary changes to decrease gout attacks and uric acid deposits.
correct answers >> Avoid beer, ale, & wine
Increase fluid intake: increases excretion of uric acid
Avoid smoked meats & high-protein diets
WHO 3 step ladder for pain medication correct answers >>
,What is not a first line for pain medication? correct answers
>> Narcotics
Recommendations for pain treatment correct answers >>
You want to start with NSAIDs first and then work your way up
from there.
types of Corticosteroid treatment correct answers >>
Prednisone, Cortisone, Dexamethasone
how do Corticosteroids work? correct answers >> Suppress
the inflammatory & immune systems by inhibiting the synthesis
of chemical mediators.
what are the chemical mediators that Corticosteroids work on?
correct answers >> Prostaglandins, leukotrienes, & histamines
Corticosteroids and inflammation correct answers >>
Decreases inflammation which decreases swelling, warmth,
redness, & pain.
Uses for corticosteroid treatment correct answers >>
Addison's disease, hormone replacement, cancer therapy
SLE, arthritis, IBD, & to suppress graft rejection
contraindications for corticosteroid treatment correct answers
>> Systemic fungal infections & with live vaccine
, Use corticosteroids cautiously with: correct answers >>
Pregnancy, kids, HTN, heart failure, renal impairment, & with
infections resistant to treatment
Patient education with corticosteroids correct answers >>
Don't discontinue abruptly, doses may need increased during
stress, symptoms of Cushing's and GI bleeding
Problem with taking Corticosteroids for greater than 6 months
correct answers >> The main thing you want to worry about is
osteoporosis it can also worsen diabetic control and patients
should report any tarry black stools or abdominal pain.
Other common side effects with Corticosteroids correct
answers >> Peptic ulcers, GI bleeding, edema, hyperglycemia,
delayed wound healing, fluid & electrolyte imbalances
Why is it important to tapper the corticosteroid? correct
answers >> Tapering must be done carefully to avoid both
recurrent activity of the underlying disease process and possible
cortisol deficiency resulting from the hypothalamic-pituitary-
adrenal axis or HPA suppression during the period of steroid
therapy
Black box warning correct answers >> Increased risk of
serious cardiovascular thrombotic events, myocardial-infarction
and stroke which can be fatal.
What increases risk of black box warning occurring with NSAIDs.
correct answers >> Risk increases with duration of use.