MARYVILLE UNIVERSITY
PHARMACOLOGY 615 EXAM 2
WITH 100% CORRECT ANSWERS
2026
Oseltamivir (Tamiflu) correct answers >> Neuramidase
Inhibitor. Oral Antiviral for influenza A&B. Works by breaking the
bond that attaches the viral particles to host cell. SE include
headache, n/v, and CNS.
Zanamivir (Relenza) correct answers >> Neuramidase
Inhibitor. Inhaled Antiviral for influenza A&B. Works by breaking
the bond that attaches the viral particles to host cell.
Contraindicated for COPD. SE include headache, n/v, and CNS.
Amantadine (Symmetrel) correct answers >> Inhaled
Antiviral for Influenza A. Works by binding to ion channels formed
by the membrane protein of viral envelope. High pKA so no
absorption in stomach. CNS side effects like dizziness.
Rimantadine (Flumadine) correct answers >> Inhaled
Antiviral for Influenza A. Works by binding to ion channels formed
by the membrane protein of viral envelope. High pKA so no
absorption in stomach. CNS side effects like dizziness.
Acyclovir, Valacyclovir, Famciclovir correct answers >>
antivirals for HSV and VZV. Block an enzyme that is essential in
,production of new viruses so virus cannot reproduce and
replicate. SE include headach and nausea.
Antivirals correct answers >> Should be takens ASAP for
effect (within 48-72 hrs of ONSET of symptoms). For shingles or
zoster, when you notice the rash, come in. For influenza, early
signs of flu, come in (sore throat, runny nose QUICK ONSET).
Amphotericin B correct answers >> Polyene antifungal for
LIFE THREATENING fungal infections. Usually have been on chemo
or poor immune systems. Disrupts the integrity of fungal cell
membrane.
Nystatin correct answers >> Polyene antifungal works by
disrupting the integrity of the fungal cell membrane but only
works for CANDIDA (unlike ammphotericin b). skin, vaginal,
oral/thrush.
itraconazole, fluconazole, posaconazole, voriconazole correct
answers >> triazole antifungals. inhibit critical enzyme that
causes a buildup of toxic substance and leads to increased fungal
membrane permeability (cell leaks out). CYP 450 system. lots of
drug interactions. SE include n/v.
Other -azoles (clotrimazole, ketoconazole, and miconazole)
correct answers >> imidazole antifungals are like the traizole
antifungals but are indicated specifically for vulvovaginal,
oropharyngeal, and tinea candidias infections. inhibit critical
enzyme that causes a buildup of toxic substance and leads to
increased fungal membrane permeability (cell leaks out). CYP 450
system. lots of drug interactions. SE include n/v.
, allylamines (lamisil) correct answers >> ORAL antifungal for
onchomycosis. works like the azole antifungals but highly active
against dermatophytes so good for toenails and fingernails that
are infected. does not work well against candida. LIVER/GI issues
because take for 12 weeeks.
Pen-Lac correct answers >> Topical antifungal indicated for
onychomycosis.
griseofulvin correct answers >> antifungal used for tinea
infections. works well for tinea capitis and works in children.
inhibits mitosis of the fungal element. liquid form. if taken with
soda can absorb better.
tolnaftate (tinactin) correct answers >> topical antifungal
used for tinea infections. tinea cruris or jock itch.
ethambutol correct answers >> antitubercular drug. inhibits
synthesis of mycolic acids (important for mycobacterial wall).
rapidly absorbed orally. NOT monotherapy. SE is optic neuritis.
Isonazid (INH) correct answers >> antitubercular drug. well
absorbed, penetrates CNS. potent. peripheral neuritis and
hepatitis are side effects.
Pyrazinamide (PZA) correct answers >> antitubercular drug.
widely distributed throughout all body tissues. bacteriostatic or
bactericidal depending on dose. hepatic toxicity side effect.
PHARMACOLOGY 615 EXAM 2
WITH 100% CORRECT ANSWERS
2026
Oseltamivir (Tamiflu) correct answers >> Neuramidase
Inhibitor. Oral Antiviral for influenza A&B. Works by breaking the
bond that attaches the viral particles to host cell. SE include
headache, n/v, and CNS.
Zanamivir (Relenza) correct answers >> Neuramidase
Inhibitor. Inhaled Antiviral for influenza A&B. Works by breaking
the bond that attaches the viral particles to host cell.
Contraindicated for COPD. SE include headache, n/v, and CNS.
Amantadine (Symmetrel) correct answers >> Inhaled
Antiviral for Influenza A. Works by binding to ion channels formed
by the membrane protein of viral envelope. High pKA so no
absorption in stomach. CNS side effects like dizziness.
Rimantadine (Flumadine) correct answers >> Inhaled
Antiviral for Influenza A. Works by binding to ion channels formed
by the membrane protein of viral envelope. High pKA so no
absorption in stomach. CNS side effects like dizziness.
Acyclovir, Valacyclovir, Famciclovir correct answers >>
antivirals for HSV and VZV. Block an enzyme that is essential in
,production of new viruses so virus cannot reproduce and
replicate. SE include headach and nausea.
Antivirals correct answers >> Should be takens ASAP for
effect (within 48-72 hrs of ONSET of symptoms). For shingles or
zoster, when you notice the rash, come in. For influenza, early
signs of flu, come in (sore throat, runny nose QUICK ONSET).
Amphotericin B correct answers >> Polyene antifungal for
LIFE THREATENING fungal infections. Usually have been on chemo
or poor immune systems. Disrupts the integrity of fungal cell
membrane.
Nystatin correct answers >> Polyene antifungal works by
disrupting the integrity of the fungal cell membrane but only
works for CANDIDA (unlike ammphotericin b). skin, vaginal,
oral/thrush.
itraconazole, fluconazole, posaconazole, voriconazole correct
answers >> triazole antifungals. inhibit critical enzyme that
causes a buildup of toxic substance and leads to increased fungal
membrane permeability (cell leaks out). CYP 450 system. lots of
drug interactions. SE include n/v.
Other -azoles (clotrimazole, ketoconazole, and miconazole)
correct answers >> imidazole antifungals are like the traizole
antifungals but are indicated specifically for vulvovaginal,
oropharyngeal, and tinea candidias infections. inhibit critical
enzyme that causes a buildup of toxic substance and leads to
increased fungal membrane permeability (cell leaks out). CYP 450
system. lots of drug interactions. SE include n/v.
, allylamines (lamisil) correct answers >> ORAL antifungal for
onchomycosis. works like the azole antifungals but highly active
against dermatophytes so good for toenails and fingernails that
are infected. does not work well against candida. LIVER/GI issues
because take for 12 weeeks.
Pen-Lac correct answers >> Topical antifungal indicated for
onychomycosis.
griseofulvin correct answers >> antifungal used for tinea
infections. works well for tinea capitis and works in children.
inhibits mitosis of the fungal element. liquid form. if taken with
soda can absorb better.
tolnaftate (tinactin) correct answers >> topical antifungal
used for tinea infections. tinea cruris or jock itch.
ethambutol correct answers >> antitubercular drug. inhibits
synthesis of mycolic acids (important for mycobacterial wall).
rapidly absorbed orally. NOT monotherapy. SE is optic neuritis.
Isonazid (INH) correct answers >> antitubercular drug. well
absorbed, penetrates CNS. potent. peripheral neuritis and
hepatitis are side effects.
Pyrazinamide (PZA) correct answers >> antitubercular drug.
widely distributed throughout all body tissues. bacteriostatic or
bactericidal depending on dose. hepatic toxicity side effect.
