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>60 years <150/90
<60 years <140/90
According to the AACE Algorithm (updated yearly), at what A1c level should you
consider putting the patient on "dual therapy" for his diabetes?
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, with an initial A1c ≥ 7.5%. If the A1c is not at goal in 3 months, the
recommendation is to intensify therapy. Triple therapy or treatment with
insulin may be needed for some patients. If the initial A1c is greater than
9.0%, the recommendation is to start with insulin (with or without other
agents), especially if the patient has symptoms of diabetes.
GLP 1 receptor agonist MOA (Albiglutide, dulaglutide , exenatide, liraglutide,
lixisenatide, and samaglutide) and SE
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Potentiates glucose-stimulated insulin secretion; animal studies suggest
that this drug may stimulate production of new beta-cells and prevent
beta-cell apoptosis
nausea, vomiting, anorexia; headache; severe hypoglycemia (when given
with insulin)
K sparing diuretics ADE
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Hyperkalemia, rash, headaches, gastrointestinal disturbances,
nephrolithiasis, don't use if k>5
How is congenital hypothyroidism diagnosed?
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, newborn screening revealing a low T4 and a high TSH
RF for HLD
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increasing age, male gender, genetic disorder of lipid metabolism, family
history of premature coronary artery disease, cigarette smoking, obesity,
HTN, HLD w/ elevated LDL and low HDL cholesterol, DM
Hyperthyroidism may affect the blood pressure
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By producing an increase in systolic and diastolic readings
Which of the following lab abnormalities is associated with subclinical
hyperthyroidism?
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Low TSH and normal free T4
the recommended initial antihypertensive agents should include
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, thiazide-type diuretic, calcium channel blocker (CCB), angiotensin-
converting enzyme (ACE) inhibitor, or an angiotensin II receptor blocker
(ARB). ACE inhibitors and ARBs should not be used in combination.
Remember, if there is a chance that the patient could become pregnant,
ACE inhibitors and ARBs are pregnancy category X.
family education for hyperthyroid management
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if taking thiomides be cautioned about rare agranulocytosis (decrease
WBC), dc if have fever >101, if jaundice, vomiting, or abd pain contact
healthcare provider, uncreased risk for afib and OP if untx, will have wt loss,
avoid strenuous exercise, no smoking
BMI and screening
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BMI is a screening tool, with low specificity, and is to be used as a
screening tool rather than a definitive diagnostic standard.
underweight BMI <18.5
normal BMI 18.5-24.9
overweight BMI 25-29.9
obesity class 1 BMI 30-34.9
obesity class 2 BMI 35-39.9
obesity class 3 BMI <40
obesity class 4 BMI 50-59.9
obesity class 5 BMI 60+