Intermediate acting insulin
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Onset 2-4 hrs
Peak 4-10 hrs
Duration 12-18 hrs
Isophane insulin (NPH, Humalin N, Novolin N)
Sulfonylureas
(-ides, glyburide, glipizide, glimepride)
MOA, side effects, contraindications
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, MOA: Stimulates insulin release from beta cells - independent of food
intake
Side effects: HYPOglycemia, weight gain, GI upset
Contraindications: Sulfa allergy, non-compliance, caution in elderly
Pregnancy: C
Lactation and meds: NO
Pt needs to eat regular meals, lowers A1C by 1-1.5%, sensitive in elderly
Hematuria
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>3RBCs
Transient: one occasion
Perisistent: >2 consecutive instances
When to start statins and what level
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Start if:
Diagnosis of ASCVD (only between 40-75) - HIGH-level statin
LDL > 190 - HIGH-level statin
Age 40-75 with DM and LDL >70 - MODERATE level statin
Age 40-75 with LDL > 70 and ASCVD >7.5% - MODERATE level statin
Diagnostics for CKD
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, Cr/GFR from first morning void
Urine sodium
LFTS
lytes
Lipids
HgbA1C
Vitamin D
PTH
Hyperthyroid
Patho
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Most common in adults and pets is Graves Disease
Autoimmune attack on thyroid TSH turnings thyroid cells ON to produce
excess t3/t4
Often in response to illness or stress
Can be persistent or transient/self limiting
Non-pharmacologic therapy for type 2 DM
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Weight loss >5% of body weight
30 mins of daily physical activity
Secondary hypertension
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, Consider if:
New onset uncontrolled hypertension
Drug resistant
Accelerated/malignant HTN
<30 yo
Exacerbation of previously controlled HTN
New onset diastolic HTN in older adult
Unprovoked/excessive hypokalemia
Microalbuminemia
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30-150 mg/day
MOA of cholesterol absorption inhibitors
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Inhibits absorption of cholesterol in small intestine in the brush border,
reduction of hepatic cholesterol stores and increased cholesterol
clearance
Management of bile acid resins
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Give this one a try later!
Onset 2-4 hrs
Peak 4-10 hrs
Duration 12-18 hrs
Isophane insulin (NPH, Humalin N, Novolin N)
Sulfonylureas
(-ides, glyburide, glipizide, glimepride)
MOA, side effects, contraindications
Give this one a try later!
, MOA: Stimulates insulin release from beta cells - independent of food
intake
Side effects: HYPOglycemia, weight gain, GI upset
Contraindications: Sulfa allergy, non-compliance, caution in elderly
Pregnancy: C
Lactation and meds: NO
Pt needs to eat regular meals, lowers A1C by 1-1.5%, sensitive in elderly
Hematuria
Give this one a try later!
>3RBCs
Transient: one occasion
Perisistent: >2 consecutive instances
When to start statins and what level
Give this one a try later!
Start if:
Diagnosis of ASCVD (only between 40-75) - HIGH-level statin
LDL > 190 - HIGH-level statin
Age 40-75 with DM and LDL >70 - MODERATE level statin
Age 40-75 with LDL > 70 and ASCVD >7.5% - MODERATE level statin
Diagnostics for CKD
Give this one a try later!
, Cr/GFR from first morning void
Urine sodium
LFTS
lytes
Lipids
HgbA1C
Vitamin D
PTH
Hyperthyroid
Patho
Give this one a try later!
Most common in adults and pets is Graves Disease
Autoimmune attack on thyroid TSH turnings thyroid cells ON to produce
excess t3/t4
Often in response to illness or stress
Can be persistent or transient/self limiting
Non-pharmacologic therapy for type 2 DM
Give this one a try later!
Weight loss >5% of body weight
30 mins of daily physical activity
Secondary hypertension
Give this one a try later!
, Consider if:
New onset uncontrolled hypertension
Drug resistant
Accelerated/malignant HTN
<30 yo
Exacerbation of previously controlled HTN
New onset diastolic HTN in older adult
Unprovoked/excessive hypokalemia
Microalbuminemia
Give this one a try later!
30-150 mg/day
MOA of cholesterol absorption inhibitors
Give this one a try later!
Inhibits absorption of cholesterol in small intestine in the brush border,
reduction of hepatic cholesterol stores and increased cholesterol
clearance
Management of bile acid resins
Give this one a try later!
