NR547 WEEK 5 EXAM QUESTIONS &
VERIFIED ANSWERS RATED 100%
CORRECT
Medications for depression - CORRECT ANSWER SSRIs
SNRIs
SDRIs
TCAs
MAOIs
SSRIs - CORRECT ANSWER -Action: inhibit 5-HT reuptake
-Examples: citalopram, escitalopram, fluoxetine, paroxetine, sertraline
-Adverse effects:
• nausea
• agitation
• diarrhea
• headache
• weight gain
• sexual side effects
SNRIs - CORRECT ANSWER -inhibit 5-HT reuptake
-inhibit NE reuptake (↑ energy, focus)
-increase DA in prefrontal cortex (↑ cognition)
-Examples: desvenlafaxine, duloxetine, levomilnacipran, venlafaxine
-Adverse effects:
• elevated blood pressure
• nausea
• sweating
• tremors
• anxiety
• insomnia
• constipation
• anorexia
• sexual dysfunction
SDRIs - CORRECT ANSWER -inhibit DA reuptake (↑alertness, motivation)
-inhibit NE reuptake (↑energy)
-Adverse effects:
• agitation
• headache
• dry mouth
, • constipation
• weight loss
TCAs - CORRECT ANSWER -Action: inhibits the reuptake of serotonin and
norepinephrine; blocks norepinephrine, histamine, and acetylcholine receptors
-Examples: amitriptyline, clomipramine, desipramine, doxepin
-Common Side Effects:
• dry mouth
• constipation
• blurred vision
• urinary retention
• sedation
• weight gain
• hypotension
• tachycardia
• sexual dysfunction
MAOIs - CORRECT ANSWER -Action: increases norepinephrine and serotonin by
inhibiting the enzyme that inactivates it
-Examples: isocarboxazid, phenelzine, tranylcypromine
-Common Side Effects:
• sedation
• dizziness
• sexual dysfunction
• hypertensive crisis
Prescribing pearls: citalopram (Celexa) - CORRECT ANSWER mild antihistamine
effects
Prescribing pearls: escitalopram (Lexapro) - CORRECT ANSWER no known drug
interactions
Prescribing pearls: fluoxetine (Prozac) - CORRECT ANSWER longest half-life
Prescribing pearls: paroxetine (Paxil) - CORRECT ANSWER also treats social anxiety
and insomnia
Prescribing pearls: fluvoxamine (Luvox) - CORRECT ANSWER treats anxious
depression smokers require increased dose
Prescribing pearls: sertraline (Zoloft) - CORRECT ANSWER also treats social anxiety
and hypersomnolence
Prescribing pearls: bupropion (Wellbutrin) - CORRECT ANSWER NDRI may improve
energy, alertness, and motivation; not first line treatment for anxiety; contraindicated in
clients with a history of seizures
VERIFIED ANSWERS RATED 100%
CORRECT
Medications for depression - CORRECT ANSWER SSRIs
SNRIs
SDRIs
TCAs
MAOIs
SSRIs - CORRECT ANSWER -Action: inhibit 5-HT reuptake
-Examples: citalopram, escitalopram, fluoxetine, paroxetine, sertraline
-Adverse effects:
• nausea
• agitation
• diarrhea
• headache
• weight gain
• sexual side effects
SNRIs - CORRECT ANSWER -inhibit 5-HT reuptake
-inhibit NE reuptake (↑ energy, focus)
-increase DA in prefrontal cortex (↑ cognition)
-Examples: desvenlafaxine, duloxetine, levomilnacipran, venlafaxine
-Adverse effects:
• elevated blood pressure
• nausea
• sweating
• tremors
• anxiety
• insomnia
• constipation
• anorexia
• sexual dysfunction
SDRIs - CORRECT ANSWER -inhibit DA reuptake (↑alertness, motivation)
-inhibit NE reuptake (↑energy)
-Adverse effects:
• agitation
• headache
• dry mouth
, • constipation
• weight loss
TCAs - CORRECT ANSWER -Action: inhibits the reuptake of serotonin and
norepinephrine; blocks norepinephrine, histamine, and acetylcholine receptors
-Examples: amitriptyline, clomipramine, desipramine, doxepin
-Common Side Effects:
• dry mouth
• constipation
• blurred vision
• urinary retention
• sedation
• weight gain
• hypotension
• tachycardia
• sexual dysfunction
MAOIs - CORRECT ANSWER -Action: increases norepinephrine and serotonin by
inhibiting the enzyme that inactivates it
-Examples: isocarboxazid, phenelzine, tranylcypromine
-Common Side Effects:
• sedation
• dizziness
• sexual dysfunction
• hypertensive crisis
Prescribing pearls: citalopram (Celexa) - CORRECT ANSWER mild antihistamine
effects
Prescribing pearls: escitalopram (Lexapro) - CORRECT ANSWER no known drug
interactions
Prescribing pearls: fluoxetine (Prozac) - CORRECT ANSWER longest half-life
Prescribing pearls: paroxetine (Paxil) - CORRECT ANSWER also treats social anxiety
and insomnia
Prescribing pearls: fluvoxamine (Luvox) - CORRECT ANSWER treats anxious
depression smokers require increased dose
Prescribing pearls: sertraline (Zoloft) - CORRECT ANSWER also treats social anxiety
and hypersomnolence
Prescribing pearls: bupropion (Wellbutrin) - CORRECT ANSWER NDRI may improve
energy, alertness, and motivation; not first line treatment for anxiety; contraindicated in
clients with a history of seizures
