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Psychopharm Exam 1 Questions with Verified Solutions – New & Modified Latest Update

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Ace your Psychopharmacology Exam 1 with this comprehensive study guide! Contains verified solutions covering neurotransmitter systems, receptor mechanisms, antipsychotic medications, schizophrenia treatment, synaptic transmission, pharmacodynamics, and pharmacokinetics. Updated with the latest modifications and clinical scenarios to help you master neuropsychiatric drug therapy.

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PSYCHOPHARM EXAM 1 QUESTIONS WITH
VERIFIED SOLUTIONS NEW MODIFIED
LATEST UPDATE


The known receptor sites for ligand-gated ion channels are:

A. Inside the channel

B. Outside the channel

C. Both inside and outside the channel

D. Ligand-gated ion channels do not have receptor sites --CORRECT
ANSWER--C. Both inside and outside the channel



Agonists cause ligand-gated ion channels to:

A. Open wider

B. Open for longer duration of time

C. Open more frequently --CORRECT ANSWER--C. Open more frequently



A receptor will stop responding to an agonist:

A. When the agonist stops binding to it

B. When the receptor becomes desensitized

C. When the receptor becomes inactivated

D. A and C


Page 1 of 56

,E. A, B, and C --CORRECT ANSWER--E. A, B, and C



Which of the following is true?

A. Positive allosteric modulation is possible only in the presence of a
neurotransmitter, while negative allosteric modulation is possible only in the
absence of a neurotransmitter

B. Negative allosteric modulation is possible only in the presence of a
neurotransmitter, while positive allosteric modulation is possible only in the
absence of a neurotransmitter

C. Both positive and negative allosteric modulations are possible only in the
absence of a neurotransmitter

D. Both positive and negative allosteric modulations are possible only in the
presence of a neurotransmitter --CORRECT ANSWER--D. Both positive and
negative allosteric modulations are possible only in the presence of a
neurotransmitter



Which of the following are involved in regulating neurotransmission via
excitation-secretion coupling?

A. Voltage-sensitive sodium channels

B. Voltage-sensitive calcium channels

C. Both A and B

D. Neither A nor B --CORRECT ANSWER--C. Both A and B



Schizophrenia and psychosis are synonymous.

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,A. True

B. False --CORRECT ANSWER--B. False



A 22-year-old woman presents with schizophrenia characterized by the
presence of positive, negative, cognitive, and affective symptoms. The symptom
dimension of schizophrenia most effectively treated with antipsychotics is:

A. Positive symptoms

B. Negative symptoms

C. Cognitive symptoms

D. Affective symptoms --CORRECT ANSWER--A. Positive symptoms



A 24-year-old male initially presents with acute auditory hallucinations and is
treated with medication. Four days later he arrives at your office for evaluation.
You observe that he is neatly dressed, avoids eye contact, and gives very short
answers to your initial questions. Which of the following questions would be
most beneficial for determining his degree of negative symptoms?

A. How often have you visited with friends in the past week?

B. Have the voices you've heard persisted or returned?

C. Have you ever thought about hurting yourself or someone else?

D. In the past week have you had difficulty concentrating? --CORRECT
ANSWER--A. How often have you visited with friends in the past week?



A serotonin molecule binds to a 5HT2A receptor causing electrical impulses to
be sent down a GABA neuron's axon terminal, eventually releasing GABA to

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, the GABA-A receptor of its postsynaptic neuron. Which type of
neurotransmission does this describe?

A. Classic synaptic neurotransmission

B. Retrograde neurotransmission

C. Volume neurotransmission

D. Signal transduction cascade --CORRECT ANSWER--A. Classic synaptic
neurotransmission



Communication between human CNS neurons at synapses is:

A. Chemical

B. Electrical --CORRECT ANSWER--A. Chemical



The direct role of transcription factors is to:

A. Cause neurotransmitter release

B. Influence gene expression

C. Synthesize enzymes

D. Trigger signal transduction cascades --CORRECT ANSWER--B. Influence
gene expression



What is epigenetics?

A. Acquired trait resulting from a change in DNA sequence

B. Acquired trait resulting from a change in gene expression


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