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, Chapter 1, The Foundation of Pharmacology: Quality and Safety
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1. A woman diagnosed with obsessive–
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compulsive disorder has been prescribed oral paroxetine hydrochloride. What is the
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expected effect for this prescription? dt dt dt dt



A. Curative effect on symptoms dt dt dt



B. Systemic effect on symptoms dt dt dt



C. Local effect on symptoms dt dt dt



D. Parenteral effect on symptoms dt dt dt




ANS: B d t



Rationale: Drugs that produce systemic effects are taken into the body, circulated through the
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bloodstream to their sites of action in various body tissues, and eventually eliminated from the
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body. Curative agents are given to cure a disease process. In this case, paroxetine hydrochlori
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de will control the symptoms but not cure the disorder. Drugs with local effects, such as sunscr
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een and local anesthetics, act mainly at the site of application. Paroxetine hydrochloride is not
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administered parenterally. Parenteral agents are administered subcutaneously, intramuscularl
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y, or intravenously.
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PTS: 1 REF: p. 3, Introduction OBJ: 1 dt dt



NAT: d t Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
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TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety dt dt dt dt dt dt dt dt



KEY: d t Integrated Process: Nursing Process dt dt dt



BLM: d Cognitive Level: Understand
t NOT: Multiple Choice dt dt d t dt




2. A client has been prescribed an antibiotic. This medication is a naturally occurring
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substance that has been cheG
mRicA
alDlyEm
SoBdOifOieSd.TWhaOt Mi s another name for this type of m
.C dt dt dt dt dt dt dt dt dt dt dt dt



edication?
A. Synthetic drug dt



B. Semisynthetic drug dt



C. Biotechnology drug dt



D. Prototype drug dt




ANS: B d t



Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances tha
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t have been chemically modified. Synthetic drugs are more standardized in their chemical char
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acteristics, more consistent in their effects, and less likely to produce allergic reactions. Biote
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chnology drugs involve manipulating DNA and RNA and recombining genes into hybrid mol
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ecules that can be inserted into living organisms. Prototype drugs are the first drug of a particu
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lar group to be developed.
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PTS: 1 REF: p. 3, Drug Sources OBJ: 1 dt dt dt



NAT: d t Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
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TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety dt dt dt dt dt dt dt dt



KEY: d t Integrated Process: Nursing Process dt dt dt



BLM: d Cognitive Level: Understand
t NOT: Multiple Choice dt dt d t dt




3. Which classification applies to morphine?
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A. Central nervous system depressant dt dt dt



B. Central nervous system stimulant dt dt dt




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