Nagelhout-Pharm 2-Exam 1 Questions and Answers 2025/2026

Nagelhout-Pharm 2-Exam 1 Questions and Answers 2025/2026 Ultra short acting neuromuscular blocker (Length of duration) - answer-Succinylcholine (5 - 15 minutes) Depolarizing NMB - answer-Succinylcholine Intermediate Acting Nondepolarizing NMBs (4) (Length of duration) - answer-Atracurium Cisatracurium Vecuronium Rocuromium (30-60 minutes) Long Acting Nondepolarizing NMB (Length of duration) - answer-Pancuronium 60-90 minutes Short Acting Nondepolarizing NMBs (Length of duration) - answer-None (20-30 minutes) NMB Reversal Agents (3) - answer-Neostigmine EdrophoniumSugammadex (not approved by FDA) NMBs work at ____ receptors - answer-Nicotinic Cholinergic (sub-m) Neurotransmitter of the NM junction - answer-acetylcholine Breaks down acetylcholine at the NM synapse/junction - answer-acetylcholinesterase Non-depolarizing agents are: agonists or antagonists - answer-Antagonist Depolarizing agents act as: agonist or antagonist?? - answer-Agonist then antagonist Onset time definition - answer-time from drug administration to maximum effect Clinical duration definition - answer-time from drug administration to 25% recovery of twitch response Total duration of action definition - answer-time from drug administration to 90% recovery of twitch response (point at which pt is recovered) Recovery index definition - answer-time from 25% to 75% recovery of twitch response (how fast?) Train of Four Index - answer-4th twitch of TOF/1st twitch of TOF Muscle stimulated by ulnar nerve in TOF - answer-Adductor pollicis