2026/l 2027l Update)l Advancedl
Pharmacologyl forl thel AGPCNPl Reviewl |l
Questionsl &l Answersl |l Gradel A|l 100%l
Correctl (Verifiedl Solutions)-Chamberlain
QUESTION
Finasteridel class
Answer:
5a-reductacel inhibitorsl forl BPH/urinaryl retention
QUESTION
finasteridel moa
Answer:
·l reducel dihydrotestosteronel productionl causingl prostatel tol shrink,l removingl mechanicall
obstructionl ofl urethra.l Takesl monthsl tol work.
QUESTION
Dutasteridel isl likel finasteridel but
Answer:
longl halfl lifel andl takesl monthsl tol clearl afterl stopping,l morel completel inl circulatingl
DHT
QUESTION
adversel effectl inl finasteride
Answer:
,·l reducedl ejaculatel volumel &l libidol (watchl dosage)l andl causesl declinel inl PSAl inl alll
men.
QUESTION
finasteridel andl pregnancy/lactation
Answer:
Teratogenicl -l dol notl letl pregnantl womenl handlel thel medication;l dol notl donatel bloodl
whilel onl dutasteridel forl 6l monthsl afterl tol avoidl transmissionl tol women.l Canl increasel
likelihoodl ofl high-gradel prostatel tumor.
QUESTION
teachingl withl finasteride
Answer:
·l Getl baselinel PSA;l monitorl psal atl 6l monthl -l ifl nol decrease,l evaluatel forl prostatel
cancer
QUESTION
drugl interactionsl withl 5l alphal reductasel inhibitorsl likel finasteride
Answer:
cyp34al inhibitorl -l azoles,l hivl meds,l grapefruitl juice
cyp34al inducerl -anti-tb,l anticonvulsants,l carbemazepine,l phenytoin
alpha1adrenergicl blockersl (tamsulosin)
PDEi-5l forl ED
testosterone
anti-androgens
warfarin
QUESTION
selectivel a1l blockerl tamsulosin,l alfuzosinl moa
Answer:
,·l Blockadel ofl alphal receptorsl relaxesl smoothl musclel inl thel bladderl neck
QUESTION
Phosphodiesterase-5l inhibitorl -Tadalafill moa
Answer:
smoothl musclel relaxationl inl thel bladder,l prostate,l andl urethra.l Canl causel hypotensionl
andl priapism
QUESTION
Alphal blocker/5-alpha-reductasel inhibitorl combo
Answer:
Tamsulosin/dutasteridel -l reducesl sizel ofl prostatel andl isl al selectivel smoothl musclel
relaxer.
QUESTION
Urinaryl retentionl medication
Answer:
Selectivel alpha-1l adrenergicl antagonistl -l Tamsulosin
QUESTION
cholinergicl treatmentl ofl urinaryl retention
Answer:
muscarinicl blockadel inl thel urinaryl tractl canl causel urinaryl hesitancyl orl retention.l Withl
someonel whol wasl catheterizedl canl treatl withl al muscarinicl agonist.l Nausea,l diarrhea,l
sweating,l bradycardia,l bronchoconstrictionl (avoidl inl asthma/COPD).
QUESTION
Treatmentl ofl UTIl inl pregnancy,l includingl dose
, Answer:
UTIsl mustl bel treatedl asl complicatedl infectionsl inl pregnancy:l Firstl linel treatment
-Trimethoprim/sulfamethoxazolel 160/800l mgl bidl 7-14l days
-Nitrofurantoinl isl contraindicatedl inl thel thirdl trimesterl ofl pregnancyl otherwisel 100mgl
BIDl forl 5l days
QUESTION
Treatmentl ofl dysurial associatedl withl UTI
Answer:
ol phenazopyridinel -l providesl symptomaticl relief
l Willl discolorl urinel tol al reddishl orange;l oral,l 100mgl tol 200l mgl takel TID
QUESTION
phenazopyridinel -l contraindication/teaching
Answer:
§l Contraindicatedl inl clientsl withl severel renall insufficiency
§l Don'tl takel forl morel thanl 2l days,l willl stainl clothes,l bodyl fluids
QUESTION
Treatmentl ofl UTIl inl patientsl withl chronicl kidneyl disease,l withl dose
Answer:
§l Amoxicillinl 500l mgl POl TIDl forl 7l daysl isl thel studyl guide'sl bestl choicel forl
uncomplicatedl UTIl inl CKDl (CrCll 25l mL/min)—monitoringl hypersensitivityl reactionl
ensuresl safety
QUESTION
Treatmentl ofl UTIl inl patientsl withl ckdl optionl 2
Answer: