Test Bank for Pharmacotherapeutics for Advanced Practice: A Practical Approach, 5th Edition

TEST BANK .



Pharmacotherapeutics forAdvanced Practice: A Practical Approach
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by Virginia Poole Arcangelo, Andrew M. Peterson
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Fifth Edition
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FULL TEST BANK!!!
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,Chapter 1 Issues for the Practitioner in Drug Therapy
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MULTIPLE.CHOICE

1. Nurse.practitioner.prescriptive.authority.is.regulated.by:
A. The.National.Council.of.State.Boards.of.Nursing
B. The.U.S..Drug.Enforcement.Administration
C. The.State.Board.of.Nursing.for.each.state
D. The.State.Board.of.Pharmacy

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2. Physician.Assistant.(PA).prescriptive.authority.is.regulated.by:
A. The.National.Council.of.State.Boards.of.Nursing
B. The.U.S..Drug.Enforcement.Administration
C. The.State.Board.of.Nursing
D. The.State.Board.of.Medical.Examiners

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3. Clinical.judgment.in.prescribing.includes:
A. Factoring.in.the.cost.to.the.patient.of.the.medication.prescribed
B. Always.prescribing.the.newest.medication.available.for.the.disease.process
C. Handing.out.drug.samples.to.poor.patients
D. Prescribing.all.generic.medications.to.cut.costs

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4. Criteria.for.choosing.an.effective.drug.for.a.disorder.include:
A. Asking.the.patient.what.drug.they.think.would.work.best.for.them
B. Consulting.nationally.recognized.guidelines.for.disease.management
C. Prescribing.medications.that.are.available.as.samples.before.writing.a.prescription
D. Following.U.S..Drug.Enforcement.Administration.(DEA).guidelines.for.pr
escribing
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5. Nurse.practitioner.practice.may.thrive.under.health-care.reform.due.to:
A. The.demonstrated.ability.of.nurse.practitioners.to.control.costs.and.improve.patient.out
comes
B. The.fact.that.nurse.practitioners.will.be.able.to.practice.independently
C. The.fact.that.nurse.practitioners.will.have.full.reimbursement.under.health-
care.reform
D. The.ability.to.shift.accountability.for.Medicaid.to.the.state.level
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Chapter 2.Pharmacokinetic Basis of Therapeutics and Pharmacodynamic
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MULTIPLE.CHOICE

1. A.patient's.nutritional.intake.and.lab.work.reflects.hypoalbuminemia..This.is.critical.to.pres
cribing.because:
A. Distribution.of.drugs.to.target.tissue.may.be.affected
B. The.solubility.of.the.drug.will.not.match.the.site.of.absorption
C. There.will.be.less.free.drug.available.to.generate.an.effect
D. Drugs.bound.to.albumin.are.readily.excreted.by.the.kidney

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2. Drugs.that.have.a.significant.first-pass.effect:
A. Must.be.given.by.the.enteral.(oral).route.only
B. Bypass.the.hepatic.circulation
C. Are.rapidly.metabolized.by.the.liver.and.may.have.little.if.any.desired.action
D. Are.converted.by.the.liver.to.more.active.and.fat-soluble.forms

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3. The.route.of.excretion.of.a.volatile.drug.will.likely.be:
A. The.kidneys
B. The.lungs
C. The.bile.and.feces
D. The.skin

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4. Medroxyprogesterone.(Depo.Provera).is.prescribed.IM.to.create.a.storage.reservoir.of.the.dru
g..Storage.reservoirs:
A. Assure.that.the.drug.will.reach.its.intended.target.tissue
B. Are.the.reason.for.giving.loading.doses
C. Increase.the.length.of.time.a.drug.is.available.and.active
D. Are.most.common.in.collagen.tissues

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5. The.NP.chooses.to.give.cephalexin.every.8.hours.based.on.knowledge.of.the.drug's:
A. Propensity.to.go.to.the.target.receptor
B. Biological.half-life
C. Pharmacodynamics
D. Safety.and.side.effects

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6. Azithromycin.dosing.requires.the.first.day's.dose.be.twice.those.of.the.other.4.days.of.the.presc
ription..This.is.considered.a.loading.dose..A.loading.dose:
A. Rapidly.achieves.drug.levels.in.the.therapeutic.range
B. Requires.four.to.five.half-lives.to.attain
C. Is.influenced.by.renal.function

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D. Is.directly.related.to.the.drug.circulating.to.the.target.tissues
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7. The.point.in.time.on.the.drug.concentration.curve.that.indicates.the.first.sign.of.a.therapeutic.effect.
is.the:
A. Minimum.adverse.effect.level
B. Peak.of.action
C. Onset.of.action
D. Therapeutic.range

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8. Phenytoin.requires.a.trough.level.be.drawn..Peak.and.trough.levels.are.done:
A. When.the.drug.has.a.wide.therapeutic.range
B. When.the.drug.will.be.administered.for.a.short.time.only
C. When.there.is.a.high.correlation.between.the.dose.and.saturation.of.receptor.sites
D. To.determine.if.a.drug.is.in.the.therapeutic.range

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9. A.laboratory.result.indicates.the.peak.level.for.a.drug.is.above.the.minimum.toxic.conc
entration..This.means.that.the:
A. Concentration.will.produce.therapeutic.effects
B. Concentration.will.produce.an.adverse.response
C. Time.between.doses.must.be.shortened
D. Duration.of.action.of.the.drug.is.too.long

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10. Drugs.that.are.receptor.agonists.may.demonstrate.what.property?
A. Irreversible.binding.to.the.drug.receptor.site
B. Up-regulation.with.chronic.use
C. Desensitization.or.down-regulation.with.continuous.use
D. Inverse.relationship.between.drug.concentration.and.drug.action

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11. Drugs.that.are.receptor.antagonists,.such.as.beta.blockers,.may.cause:
A. Down-regulation.of.the.drug.receptor
B. An.exaggerated.response.if.abruptly.discontinued
C. Partial.blockade.of.the.effects.of.agonist.drugs
D. An.exaggerated.response.to.competitive.drug.agonists

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12. Factors.that.affect.gastric.drug.absorption.include:
A. Liver.enzyme.activity
B. Protein-binding.properties.of.the.drug.molecule
C. Lipid.solubility.of.the.drug
D. Ability.to.chew.and.swallow

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