1|Page
NR 507 ADVANCED PATHOPHYSIOLOGY MIDTERM
EXAM NEWEST VERSION 2026 WITH COMPLETE
QUESTIONS AND SOLUTION 100% VERIFIED
ANSWERS WITH RATIONALES A+ GRADED||NEWEST
EXAM!!!
Mr. Mann, age 50, presents to the Emergency Department
with his wife for complaints of palpitations, feeling of panic
with shakiness, headache, nausea for the past two hours.
Upon arrival BP is 210/105. His medical history is
significant for GERD and HTN. He takes Prilosec OTC
daily and lisinopril 10mg daily. He has no known
medication allergies. His family history includes HTN and
cardiovascular disease in father, osteoporosis, anxiety,
and HTN in mother, and breast cancer in only sister. His
wife states the patient did this a couple of weeks ago on
two different occasions, but the symptoms went away in
just one or two minutes. His physical exam reveals mild
diaphoresis, epigastric tenderness, and generalized
trembling. What diagnosis does this patient's presentation
most closely represent?
A. Myxedema Coma
B. Addison's Disease
C. Thyrotoxicosis
D. Pheochromocytoma - ANSWER-D. pheochromocytoma
,2|Page
A 72-year-old male is brought to the ED in a coma. He
was delivered to the ED from a nursing home and was
reported by the nursing home staff to have had a seizure
that lasted less than 1 minute. He was subsequently
confused and soon thereafter entered a comatose state.
His medical history is significant for Type II DM requiring
insulin, HTN, and mild CHF. In the ED, the patient is very
lethargic and responds only to painful stimuli. His vital
signs are stable. The list of differential diagnoses that can
cause seizure and coma. What is the most important
diagnostic study to do immediately?
A. Serum toxicology
B. CT head without contrast
C. CT head with contrast
D. Serum glucose - ANSWER-D. serum glucose
A 2-year-old child who recently immigrated to the United
States has failure to thrive. The child is short, with course
facial features, a protruding tongue, and an umbilical
hernia. Profound mental retardation is apparent as the
child matures. These findings are best explained by a lack
of:
A. Somatostatin
B. Cortisol
C. Thyroxine (T4)
,3|Page
D. Norepinephrine - ANSWER-C. thyroxine
A 36-year-old female presents to the clinic with a history of
fatigue for the past few months. She does not have any
other complaints. After a thorough medical history, she
admits to mild constipation that is not troublesome for her.
She reports a 5 lb weight gain over the past 6 months,
which she attributes to living a more sedentary life of late
due to her fatigue and lethargy. Her physical examination
is unremarkable; her thyroid does not seem enlarged,
although her face is slightly puffy. You order thyroid
function studies, which show an elevated Thyroid
Stimulating Hormone (TSH). What is the diagnosis?
A. Hashimoto's thyroiditis
B. Grave's disease
C. Addison's Disease
D. Cushing's syndrome - ANSWER-A. Hashimoto's
thyroiditis
A 35-year-old female brings her 13-year-old son to the
clinic reporting that he has developed some strange
behaviors. She reports he cannot leave the house to go to
school each morning without reorganizing his bookshelf
and brushes his teeth 3 times before bed. She also
expresses frustration that if daily plans change, he
, 4|Page
becomes tearful and hostile. You suspect that this child
may have:
A. post-traumatic stress disorder
B. obsessive compulsive disorder
C. depression
D. social anxiety disorder - ANSWER-B. OCD
A 45-year-old male presents to the clinic with a chief
complaint of a daily chronic, episodic headache for the
past 7 weeks. He reports that he has been experiencing
insomnia due to the symptoms which are waking him up at
night. He reports that they last anywhere from 15 minutes
to 3 hours. What is the most likely diagnosis?
A. brain tumor
B. migraine headache
C. tension headache
D. cluster headache - ANSWER-D
A 44-year-old male injection drug user is admitted with a 1
day history of increasing headache and high fever. Head
computed tomography (CT) does not reveal a mass lesion
or midline shift. A lumbar puncture is performed; the
cerebral spinal fluid (CSF) protein concentration is
increased, but the glucose level is decreased. Which of
NR 507 ADVANCED PATHOPHYSIOLOGY MIDTERM
EXAM NEWEST VERSION 2026 WITH COMPLETE
QUESTIONS AND SOLUTION 100% VERIFIED
ANSWERS WITH RATIONALES A+ GRADED||NEWEST
EXAM!!!
Mr. Mann, age 50, presents to the Emergency Department
with his wife for complaints of palpitations, feeling of panic
with shakiness, headache, nausea for the past two hours.
Upon arrival BP is 210/105. His medical history is
significant for GERD and HTN. He takes Prilosec OTC
daily and lisinopril 10mg daily. He has no known
medication allergies. His family history includes HTN and
cardiovascular disease in father, osteoporosis, anxiety,
and HTN in mother, and breast cancer in only sister. His
wife states the patient did this a couple of weeks ago on
two different occasions, but the symptoms went away in
just one or two minutes. His physical exam reveals mild
diaphoresis, epigastric tenderness, and generalized
trembling. What diagnosis does this patient's presentation
most closely represent?
A. Myxedema Coma
B. Addison's Disease
C. Thyrotoxicosis
D. Pheochromocytoma - ANSWER-D. pheochromocytoma
,2|Page
A 72-year-old male is brought to the ED in a coma. He
was delivered to the ED from a nursing home and was
reported by the nursing home staff to have had a seizure
that lasted less than 1 minute. He was subsequently
confused and soon thereafter entered a comatose state.
His medical history is significant for Type II DM requiring
insulin, HTN, and mild CHF. In the ED, the patient is very
lethargic and responds only to painful stimuli. His vital
signs are stable. The list of differential diagnoses that can
cause seizure and coma. What is the most important
diagnostic study to do immediately?
A. Serum toxicology
B. CT head without contrast
C. CT head with contrast
D. Serum glucose - ANSWER-D. serum glucose
A 2-year-old child who recently immigrated to the United
States has failure to thrive. The child is short, with course
facial features, a protruding tongue, and an umbilical
hernia. Profound mental retardation is apparent as the
child matures. These findings are best explained by a lack
of:
A. Somatostatin
B. Cortisol
C. Thyroxine (T4)
,3|Page
D. Norepinephrine - ANSWER-C. thyroxine
A 36-year-old female presents to the clinic with a history of
fatigue for the past few months. She does not have any
other complaints. After a thorough medical history, she
admits to mild constipation that is not troublesome for her.
She reports a 5 lb weight gain over the past 6 months,
which she attributes to living a more sedentary life of late
due to her fatigue and lethargy. Her physical examination
is unremarkable; her thyroid does not seem enlarged,
although her face is slightly puffy. You order thyroid
function studies, which show an elevated Thyroid
Stimulating Hormone (TSH). What is the diagnosis?
A. Hashimoto's thyroiditis
B. Grave's disease
C. Addison's Disease
D. Cushing's syndrome - ANSWER-A. Hashimoto's
thyroiditis
A 35-year-old female brings her 13-year-old son to the
clinic reporting that he has developed some strange
behaviors. She reports he cannot leave the house to go to
school each morning without reorganizing his bookshelf
and brushes his teeth 3 times before bed. She also
expresses frustration that if daily plans change, he
, 4|Page
becomes tearful and hostile. You suspect that this child
may have:
A. post-traumatic stress disorder
B. obsessive compulsive disorder
C. depression
D. social anxiety disorder - ANSWER-B. OCD
A 45-year-old male presents to the clinic with a chief
complaint of a daily chronic, episodic headache for the
past 7 weeks. He reports that he has been experiencing
insomnia due to the symptoms which are waking him up at
night. He reports that they last anywhere from 15 minutes
to 3 hours. What is the most likely diagnosis?
A. brain tumor
B. migraine headache
C. tension headache
D. cluster headache - ANSWER-D
A 44-year-old male injection drug user is admitted with a 1
day history of increasing headache and high fever. Head
computed tomography (CT) does not reveal a mass lesion
or midline shift. A lumbar puncture is performed; the
cerebral spinal fluid (CSF) protein concentration is
increased, but the glucose level is decreased. Which of
