NURS 6521 – Advanced Pharmacology | Version 1 (Questions 1–100)
Cardiovascular Drugs
1. Which of the following drugs is a selective beta-1 blocker?
A) Propranolol
B) Metoprolol ✅
C) Labetalol
D) Carvedilol
2. A patient receiving amiodarone should be monitored primarily for:
A) Nephrotoxicity
B) Hepatotoxicity ✅
C) Hypoglycemia
D) Hyperkalemia
3. Which ACE inhibitor side effect is most common?
A) Hypokalemia
B) Persistent dry cough ✅
C) Bradycardia
D) Hypernatremia
4. The first-line drug for chronic heart failure with reduced ejection fraction is:
A) Digoxin
B) ACE inhibitors ✅
C) Beta-2 agonists
D) NSAIDs
5. A patient on digoxin presents with nausea and visual disturbances. The nurse
suspects:
A) Hypokalemia
B) Digoxin toxicity ✅
C) Hypernatremia
D) Bradycardia
6. Which drug is used for rapid reversal of heparin?
A) Vitamin K
B) Protamine sulfate ✅
C) Warfarin
D) Atropine
7. Which diuretic class is most likely to cause hypokalemia?
A) Loop diuretics ✅
B) Thiazide diuretics
C) Potassium-sparing diuretics
D) Carbonic anhydrase inhibitors
8. Lisinopril is contraindicated in which condition?
A) Hypertension
B) Pregnancy ✅
,C) Heart failure
D) Diabetes
9. Which drug is an anti-platelet agent?
A) Warfarin
B) Heparin
C) Clopidogrel ✅
D) Dabigatran
10. Which drug class lowers cholesterol by inhibiting HMG-CoA reductase?
A) Statins ✅
B) Fibrates
C) Bile acid sequestrants
D) Niacin
Endocrine & Metabolic Drugs
11. First-line therapy for Type 2 diabetes is:
A) Glyburide
B) Metformin ✅
C) Pioglitazone
D) Insulin
12. Which drug treats hypothyroidism?
A) Methimazole
B) Levothyroxine ✅
C) Propylthiouracil
D) Iodine
13. Which anti-thyroid drug is preferred during the first trimester of pregnancy?
A) Methimazole
B) Propylthiouracil ✅
C) Levothyroxine
D) Liothyronine
14. A patient on insulin therapy should monitor for:
A) Hypoglycemia ✅
B) Hypertension
C) Bradycardia
D) Hypernatremia
15. Which oral hypoglycemic is a sulfonylurea?
A) Metformin
B) Glipizide ✅
C) Pioglitazone
D) Sitagliptin
, 16. Which drug is used to treat adrenal insufficiency?
A) Prednisone ✅
B) Hydralazine
C) Furosemide
D) Metoprolol
17. Which of the following drugs is contraindicated in Cushing’s syndrome?
A) Prednisone
B) Dexamethasone ✅
C) Fludrocortisone
D) Levothyroxine
18. Which electrolyte imbalance is common with thiazide diuretics?
A) Hyperkalemia
B) Hypokalemia ✅
C) Hypercalcemia
D) Hyponatremia
19. A patient taking levothyroxine should avoid:
A) Calcium supplements ✅
B) Vitamin D
C) Iron-free multivitamins
D) Fiber-rich diet
20. The mechanism of action of metformin is:
A) Stimulates insulin secretion
B) Reduces hepatic glucose production ✅
C) Increases glucose absorption
D) Inhibits pancreatic beta cells
Antibiotics & Anti-infectives
21. Which antibiotic inhibits bacterial cell wall synthesis?
A) Penicillin ✅
B) Tetracycline
C) Erythromycin
D) Ciprofloxacin
22. Aminoglycosides require monitoring of:
A) Liver function
B) Kidney function ✅
C) Glucose levels
D) Blood pressure
23. Which antibiotic is teratogenic?
A) Amoxicillin
B) Tetracycline ✅
Cardiovascular Drugs
1. Which of the following drugs is a selective beta-1 blocker?
A) Propranolol
B) Metoprolol ✅
C) Labetalol
D) Carvedilol
2. A patient receiving amiodarone should be monitored primarily for:
A) Nephrotoxicity
B) Hepatotoxicity ✅
C) Hypoglycemia
D) Hyperkalemia
3. Which ACE inhibitor side effect is most common?
A) Hypokalemia
B) Persistent dry cough ✅
C) Bradycardia
D) Hypernatremia
4. The first-line drug for chronic heart failure with reduced ejection fraction is:
A) Digoxin
B) ACE inhibitors ✅
C) Beta-2 agonists
D) NSAIDs
5. A patient on digoxin presents with nausea and visual disturbances. The nurse
suspects:
A) Hypokalemia
B) Digoxin toxicity ✅
C) Hypernatremia
D) Bradycardia
6. Which drug is used for rapid reversal of heparin?
A) Vitamin K
B) Protamine sulfate ✅
C) Warfarin
D) Atropine
7. Which diuretic class is most likely to cause hypokalemia?
A) Loop diuretics ✅
B) Thiazide diuretics
C) Potassium-sparing diuretics
D) Carbonic anhydrase inhibitors
8. Lisinopril is contraindicated in which condition?
A) Hypertension
B) Pregnancy ✅
,C) Heart failure
D) Diabetes
9. Which drug is an anti-platelet agent?
A) Warfarin
B) Heparin
C) Clopidogrel ✅
D) Dabigatran
10. Which drug class lowers cholesterol by inhibiting HMG-CoA reductase?
A) Statins ✅
B) Fibrates
C) Bile acid sequestrants
D) Niacin
Endocrine & Metabolic Drugs
11. First-line therapy for Type 2 diabetes is:
A) Glyburide
B) Metformin ✅
C) Pioglitazone
D) Insulin
12. Which drug treats hypothyroidism?
A) Methimazole
B) Levothyroxine ✅
C) Propylthiouracil
D) Iodine
13. Which anti-thyroid drug is preferred during the first trimester of pregnancy?
A) Methimazole
B) Propylthiouracil ✅
C) Levothyroxine
D) Liothyronine
14. A patient on insulin therapy should monitor for:
A) Hypoglycemia ✅
B) Hypertension
C) Bradycardia
D) Hypernatremia
15. Which oral hypoglycemic is a sulfonylurea?
A) Metformin
B) Glipizide ✅
C) Pioglitazone
D) Sitagliptin
, 16. Which drug is used to treat adrenal insufficiency?
A) Prednisone ✅
B) Hydralazine
C) Furosemide
D) Metoprolol
17. Which of the following drugs is contraindicated in Cushing’s syndrome?
A) Prednisone
B) Dexamethasone ✅
C) Fludrocortisone
D) Levothyroxine
18. Which electrolyte imbalance is common with thiazide diuretics?
A) Hyperkalemia
B) Hypokalemia ✅
C) Hypercalcemia
D) Hyponatremia
19. A patient taking levothyroxine should avoid:
A) Calcium supplements ✅
B) Vitamin D
C) Iron-free multivitamins
D) Fiber-rich diet
20. The mechanism of action of metformin is:
A) Stimulates insulin secretion
B) Reduces hepatic glucose production ✅
C) Increases glucose absorption
D) Inhibits pancreatic beta cells
Antibiotics & Anti-infectives
21. Which antibiotic inhibits bacterial cell wall synthesis?
A) Penicillin ✅
B) Tetracycline
C) Erythromycin
D) Ciprofloxacin
22. Aminoglycosides require monitoring of:
A) Liver function
B) Kidney function ✅
C) Glucose levels
D) Blood pressure
23. Which antibiotic is teratogenic?
A) Amoxicillin
B) Tetracycline ✅
