LAT Laboratory Animal Technician Exam with accurate
|| || || || || || ||
detailed solutions ||
U.S. Government provides approximately how much in research/development funds spent by
|| || || || || || || || || || ||
college and university? - ✔✔2/3 || || || ||
What information is important on grant applications to request funds? - ✔✔Detailed description
|| || || || || || || || || || || || ||
of research goals, scientific basis of study, and review of relevant literature and all procedures to
|| || || || || || || || || || || || || || || ||
be performed
||
What is the difference between NIH & NSF? - ✔✔NIH: primary granting agency: academia,
|| || || || || || || || || || || || || ||
federal agencies, biomedical research
|| || || ||
NSF: Basic research in math, medicine, and biology
|| || || || || || ||
The USDA stands for what? - ✔✔United States Department of Agriculture
|| || || || || || || || || ||
The USDA is responsible for what? - ✔✔Enforces and amends AWA
|| || || || || || || || || ||
Auction, sale, exhibit, transport, breeding, or conduct of research with animals
|| || || || || || || || || ||
Animals exempt from AWA || || ||
Research institutions mst register with || || || ||
Supply annual reports || ||
Inspection records through the FOIA || || || ||
Unscheduled inspection once per year || || || ||
What does the FOIA stand for? - ✔✔Freedom of Information Act - provides the USDA's
|| || || || || || || || || || || || || || ||
inspection records ||
,What is the Public Health Service Policy? - ✔✔Institutions which receive funding from PHS and
|| || || || || || || || || || || || || || ||
NIH must follow these guidelines, requires filing of an Amimal Welfare Assurance document that
|| || || || || || || || || || || || ||
demonstrates the institution is following the Guid, PHS policy, AWA, and any other applicable
|| || || || || || || || || || || || || || ||
laws
The FDA has many responsibilites including: - ✔✔Assures that new drugs and medical devices
|| || || || || || || || || || || || || ||
are safe and effective before approved for use in humans
|| || || || || || || || ||
Monitors drug approval || ||
Includes human, and veterinary drugs, food, and medical devices
|| || || || || || || ||
Requires that effectiveness be demonstrated through well controlled investigations
|| || || || || || || ||
What is GLP? - ✔✔Good Laboratory Practices
|| || || || || ||
Established in 1978 with implementation of laboratory audits and inspection programs || || || || || || || || || ||
Details requirements for QA and SOPs || || || || ||
What is the importance of importation and transportations regulations? - ✔✔For the protection of
|| || || || || || || || || || || || || ||
humans and environment from potential disease carrying organisms
|| || || || || || ||
Which agencies control importation? - ✔✔CDC, USDA, and US Fish & Wildlife Service
|| || || || || || || || || || || ||
Institutional polices are established for: - ✔✔facility operations || || || || || || ||
care and use procedures
|| || ||
veterinary support ||
physical plant ||
Standard operating procedures relate to: - ✔✔wall aspects of animal care and support
|| || || || || || || || || || || ||
personnel management ||
health surveillance of animals and personnel
|| || || || ||
equipment
,investigators
What are the functions of IACUCs and who mandates? - ✔✔mandated by AWA, PHS policy, and
|| || || || || || || || || || || || || || || ||
the Guide
||
Review and approve protocols for animal use
|| || || || || ||
Review animal use program and perform animal facilities inspections at least every 6 months
|| || || || || || || || || || || || ||
What has to happen before animal research can begin? - ✔✔principal investigator provides
|| || || || || || || || || || || || ||
written details of how animals will be used in the research project
|| || || || || || || || || || ||
IACUC must review all protocols using animals and must approve all protocols before any animal
|| || || || || || || || || || || || || ||
research can begin
|| || ||
What does the IACUC determine? - ✔✔Can deny permission ro start a project
|| || || || || || || || || || || ||
can stop a research peoject
|| || || ||
Ensures compliance with regulations || || ||
Reviews complete protocols at least every 3 years; reviews updates to protocols yearly
|| || || || || || || || || || || ||
What is the AAALAC, International? - ✔✔Association for Assessment and Accreditation of
|| || || || || || || || || || || ||
Laboratory Animal Care, International || || ||
Non-profit organization that provides a mechanism for peer review of animal care and use
|| || || || || || || || || || || || || ||
programs by scientific community || || ||
Detailed application with information on facilities, procedures, programs, and research animals to
|| || || || || || || || || || || ||
use
Annual report must be submitted to AAALAC on status of animal care program
|| || || || || || || || || || || ||
Site inspection and program evaluation every 3 years
|| || || || || || ||
Why is it important to keep accurate, up-to-date records? - ✔✔Determine if procedures are
|| || || || || || || || || || || || || ||
followed according to established standards || || || ||
Determine whether environmental controls are properly maintained || || || || || ||
, Improve facility efficiency and effectivness || || || ||
What is PHS Policy? - ✔✔All assurance records related directly to grant applications, research
|| || || || || || || || || || || || || ||
proposals, and changes of research activities > 3yrs after completion || || || || || || || || ||
Centralized - ✔✔Serves all the institution's animal care needs; 1 director for entire institution; All
|| || || || || || || || || || || || || ||
personnel associated with the animal facility; All other purchases, per diem, depreciation,
|| || || || || || || || || || || || ||
inventories, operational costs, and supplies || || || ||
Decentralized - ✔✔Each department has own animal facility and operating budget; each || || || || || || || || || || || ||
department has own animals, supplies, equipment and animal care staffing || || || || || || || || ||
Direct costs - ✔✔Salaries, fringe benefits, equipment, supplies, and operational exprenses
|| || || || || || || || || || ||
(depend on # animals being housed) || || || || ||
Indirect Costs - ✔✔physical plant, energy costs, depreciation, heating rooms
|| || || || || || || || ||
Cost Centers - ✔✔Cage washing, laboratory services
|| || || || || ||
Why is cost accounting important? - ✔✔Individulal costs used for projecting future cost;
|| || || || || || || || || || || || ||
comparisons reveal areas in which costs can be reduced; per diem components (expense to || || || || || || || || || || || || || ||
maintain 1 animal for 1 day) || || || || ||
Calculating per diem charges - ✔✔Internal direct costs are incurred for the husbandry of animals
|| || || || || || || || || || || || || || ||
and for other services provided by the animal facility for the benefits of special projects
|| || || || || || || || || || || || || ||
If total costs of maintaining a colony of cats is $27,375 over a 1 year period and the average daily
|| || || || || || || || || || || || || || || || || || || ||
census is 25 cats, what is the per diem charge needed to recover these costs? - ✔✔Divide $27,375
|| || || || || || || || || || || || || || || || || ||
by 365 and multiply the result by 25 = 3.00
|| || || || || || || || ||
|| || || || || || ||
detailed solutions ||
U.S. Government provides approximately how much in research/development funds spent by
|| || || || || || || || || || ||
college and university? - ✔✔2/3 || || || ||
What information is important on grant applications to request funds? - ✔✔Detailed description
|| || || || || || || || || || || || ||
of research goals, scientific basis of study, and review of relevant literature and all procedures to
|| || || || || || || || || || || || || || || ||
be performed
||
What is the difference between NIH & NSF? - ✔✔NIH: primary granting agency: academia,
|| || || || || || || || || || || || || ||
federal agencies, biomedical research
|| || || ||
NSF: Basic research in math, medicine, and biology
|| || || || || || ||
The USDA stands for what? - ✔✔United States Department of Agriculture
|| || || || || || || || || ||
The USDA is responsible for what? - ✔✔Enforces and amends AWA
|| || || || || || || || || ||
Auction, sale, exhibit, transport, breeding, or conduct of research with animals
|| || || || || || || || || ||
Animals exempt from AWA || || ||
Research institutions mst register with || || || ||
Supply annual reports || ||
Inspection records through the FOIA || || || ||
Unscheduled inspection once per year || || || ||
What does the FOIA stand for? - ✔✔Freedom of Information Act - provides the USDA's
|| || || || || || || || || || || || || || ||
inspection records ||
,What is the Public Health Service Policy? - ✔✔Institutions which receive funding from PHS and
|| || || || || || || || || || || || || || ||
NIH must follow these guidelines, requires filing of an Amimal Welfare Assurance document that
|| || || || || || || || || || || || ||
demonstrates the institution is following the Guid, PHS policy, AWA, and any other applicable
|| || || || || || || || || || || || || || ||
laws
The FDA has many responsibilites including: - ✔✔Assures that new drugs and medical devices
|| || || || || || || || || || || || || ||
are safe and effective before approved for use in humans
|| || || || || || || || ||
Monitors drug approval || ||
Includes human, and veterinary drugs, food, and medical devices
|| || || || || || || ||
Requires that effectiveness be demonstrated through well controlled investigations
|| || || || || || || ||
What is GLP? - ✔✔Good Laboratory Practices
|| || || || || ||
Established in 1978 with implementation of laboratory audits and inspection programs || || || || || || || || || ||
Details requirements for QA and SOPs || || || || ||
What is the importance of importation and transportations regulations? - ✔✔For the protection of
|| || || || || || || || || || || || || ||
humans and environment from potential disease carrying organisms
|| || || || || || ||
Which agencies control importation? - ✔✔CDC, USDA, and US Fish & Wildlife Service
|| || || || || || || || || || || ||
Institutional polices are established for: - ✔✔facility operations || || || || || || ||
care and use procedures
|| || ||
veterinary support ||
physical plant ||
Standard operating procedures relate to: - ✔✔wall aspects of animal care and support
|| || || || || || || || || || || ||
personnel management ||
health surveillance of animals and personnel
|| || || || ||
equipment
,investigators
What are the functions of IACUCs and who mandates? - ✔✔mandated by AWA, PHS policy, and
|| || || || || || || || || || || || || || || ||
the Guide
||
Review and approve protocols for animal use
|| || || || || ||
Review animal use program and perform animal facilities inspections at least every 6 months
|| || || || || || || || || || || || ||
What has to happen before animal research can begin? - ✔✔principal investigator provides
|| || || || || || || || || || || || ||
written details of how animals will be used in the research project
|| || || || || || || || || || ||
IACUC must review all protocols using animals and must approve all protocols before any animal
|| || || || || || || || || || || || || ||
research can begin
|| || ||
What does the IACUC determine? - ✔✔Can deny permission ro start a project
|| || || || || || || || || || || ||
can stop a research peoject
|| || || ||
Ensures compliance with regulations || || ||
Reviews complete protocols at least every 3 years; reviews updates to protocols yearly
|| || || || || || || || || || || ||
What is the AAALAC, International? - ✔✔Association for Assessment and Accreditation of
|| || || || || || || || || || || ||
Laboratory Animal Care, International || || ||
Non-profit organization that provides a mechanism for peer review of animal care and use
|| || || || || || || || || || || || || ||
programs by scientific community || || ||
Detailed application with information on facilities, procedures, programs, and research animals to
|| || || || || || || || || || || ||
use
Annual report must be submitted to AAALAC on status of animal care program
|| || || || || || || || || || || ||
Site inspection and program evaluation every 3 years
|| || || || || || ||
Why is it important to keep accurate, up-to-date records? - ✔✔Determine if procedures are
|| || || || || || || || || || || || || ||
followed according to established standards || || || ||
Determine whether environmental controls are properly maintained || || || || || ||
, Improve facility efficiency and effectivness || || || ||
What is PHS Policy? - ✔✔All assurance records related directly to grant applications, research
|| || || || || || || || || || || || || ||
proposals, and changes of research activities > 3yrs after completion || || || || || || || || ||
Centralized - ✔✔Serves all the institution's animal care needs; 1 director for entire institution; All
|| || || || || || || || || || || || || ||
personnel associated with the animal facility; All other purchases, per diem, depreciation,
|| || || || || || || || || || || || ||
inventories, operational costs, and supplies || || || ||
Decentralized - ✔✔Each department has own animal facility and operating budget; each || || || || || || || || || || || ||
department has own animals, supplies, equipment and animal care staffing || || || || || || || || ||
Direct costs - ✔✔Salaries, fringe benefits, equipment, supplies, and operational exprenses
|| || || || || || || || || || ||
(depend on # animals being housed) || || || || ||
Indirect Costs - ✔✔physical plant, energy costs, depreciation, heating rooms
|| || || || || || || || ||
Cost Centers - ✔✔Cage washing, laboratory services
|| || || || || ||
Why is cost accounting important? - ✔✔Individulal costs used for projecting future cost;
|| || || || || || || || || || || || ||
comparisons reveal areas in which costs can be reduced; per diem components (expense to || || || || || || || || || || || || || ||
maintain 1 animal for 1 day) || || || || ||
Calculating per diem charges - ✔✔Internal direct costs are incurred for the husbandry of animals
|| || || || || || || || || || || || || || ||
and for other services provided by the animal facility for the benefits of special projects
|| || || || || || || || || || || || || ||
If total costs of maintaining a colony of cats is $27,375 over a 1 year period and the average daily
|| || || || || || || || || || || || || || || || || || || ||
census is 25 cats, what is the per diem charge needed to recover these costs? - ✔✔Divide $27,375
|| || || || || || || || || || || || || || || || || ||
by 365 and multiply the result by 25 = 3.00
|| || || || || || || || ||
