,Prophecy Core Mandatory Part II Final Exam Study Guide 2026/2027
100 Detailed Questions & Answers with Correct Answers Marked (✓)
Section 1: Infection Prevention & Control (15 Questions)
1. What is the single most effective way to prevent the spread of infection?
A. Wearing a gown
B. Using antimicrobial sprays
C. Hand hygiene ✓
D. Placing the patient in isolation
Explanation: The CDC and WHO identify hand hygiene (handwashing with soap/water or use of
alcohol-based hand rub) as the most critical measure for preventing cross-transmission.
2. Which of the following is an example of contact transmission?
A. Inhaling aerosolized droplets from a cough
B. A tick bite
C. Touching a contaminated bedside table ✓
D. Drinking contaminated water
Explanation: Contact transmission involves the physical transfer of microorganisms via direct
(person-to-person) or indirect (contaminated object) contact.
3. Proper sequence for donning PPE (after hand hygiene) is:
A. Gown, mask, goggles, gloves
B. Gown, gloves, mask, goggles
C. Gown, mask/respirator, goggles/face shield, gloves ✓
D. Gloves, gown, goggles, mask
Explanation: This sequence (CDC standard) prevents contamination of clothing and face. Gloves
are always last.
4. Proper sequence for doffing PPE is:
A. Gloves, goggles, gown, mask ✓
B. Gown, gloves, mask, goggles
C. Mask, goggles, gloves, gown
D. Goggles, mask, gloves, gown
Explanation: Gloves are removed first (most contaminated), followed by eye protection, gown,
and finally mask/respirator to protect mucous membranes.
5. Standard Precautions apply to:
A. Only patients with diagnosed infections
,B. Only blood and body fluids with visible blood
C. All patients, all the time, regardless of diagnosis ✓
D. Only patients in isolation rooms
Explanation: Standard Precautions are the minimum infection prevention practices that apply to
all patient care, regardless of infection status.
6. A patient with Clostridioides difficile (C. diff) should be placed on:
A. Droplet Precautions
B. Contact Precautions ✓
C. Airborne Precautions
D. Standard Precautions only
Explanation: C. diff spores are spread via the fecal-oral route through contact with
contaminated surfaces or hands. Contact Precautions are required.
7. A patient with active pulmonary Tuberculosis requires:
A. Contact Precautions
B. Droplet Precautions
C. Airborne Infection Isolation Room (AIIR) ✓
D. Standard and Contact Precautions
Explanation: TB is transmitted via airborne droplet nuclei (small particles) that remain
suspended in air, requiring a negative pressure AIIR and N95 respirator.
8. The appropriate PPE for entering the room of a patient on Droplet Precautions for Influenza
is:
A. N95 respirator, gown, gloves
B. Surgical mask, gown, gloves ✓
C. N95 respirator only
D. Gown and gloves only
Explanation: Droplets are larger particles that don't remain suspended; a surgical mask is
sufficient. Gown/gloves are used based on anticipated contact.
9. An N95 respirator must be:
A. Used for all patients on isolation
B. Discarded after leaving any patient room
C. Reused for the same patient multiple times
D. Fit-tested for each individual wearer ✓
Explanation: N95s require an initial fit test to ensure a proper seal, and a user seal check each
time they are donned.
, 10. A needle safety device (engineered sharp) is an example of which level of the Hierarchy of
Controls?
A. Personal Protective Equipment (PPE)
B. Administrative Controls
C. Engineering Controls ✓
D. Elimination
Explanation: Engineering controls (like safer needle devices, sharps containers) physically
remove or isolate the hazard from the worker.
11. After a needlestick injury, the FIRST action is to:
A. Report to a supervisor
B. Complete an incident report
C. Wash the area with soap and water ✓
D. Go to the Emergency Department
Explanation: Immediate first aid is crucial: wash the wound with soap and water or flush
mucous membranes with water.
12. Multi-dose vials should be:
A. Used for one patient only
B. Dated when opened and discarded per facility policy ✓
C. Stored at the bedside for easy access
D. Used until empty, regardless of time
*Explanation: To prevent contamination, multi-dose vials must be labeled with the date of first
use and discarded within a specified time (e.g., 28 days).*
13. The primary purpose of a sterile field is to:
A. Organize equipment
B. Reduce the time of a procedure
C. Prevent microbial contamination of the surgical site ✓
D. Protect the healthcare worker
Explanation: A sterile field provides a microorganism-free area to protect the patient during
invasive procedures.
14. Surgical asepsis refers to:
A. Clean technique (e.g., bed bath)
B. The absence of all microorganisms in a defined area ✓
C. Reducing the number of microorganisms
D. The use of disinfectants only
100 Detailed Questions & Answers with Correct Answers Marked (✓)
Section 1: Infection Prevention & Control (15 Questions)
1. What is the single most effective way to prevent the spread of infection?
A. Wearing a gown
B. Using antimicrobial sprays
C. Hand hygiene ✓
D. Placing the patient in isolation
Explanation: The CDC and WHO identify hand hygiene (handwashing with soap/water or use of
alcohol-based hand rub) as the most critical measure for preventing cross-transmission.
2. Which of the following is an example of contact transmission?
A. Inhaling aerosolized droplets from a cough
B. A tick bite
C. Touching a contaminated bedside table ✓
D. Drinking contaminated water
Explanation: Contact transmission involves the physical transfer of microorganisms via direct
(person-to-person) or indirect (contaminated object) contact.
3. Proper sequence for donning PPE (after hand hygiene) is:
A. Gown, mask, goggles, gloves
B. Gown, gloves, mask, goggles
C. Gown, mask/respirator, goggles/face shield, gloves ✓
D. Gloves, gown, goggles, mask
Explanation: This sequence (CDC standard) prevents contamination of clothing and face. Gloves
are always last.
4. Proper sequence for doffing PPE is:
A. Gloves, goggles, gown, mask ✓
B. Gown, gloves, mask, goggles
C. Mask, goggles, gloves, gown
D. Goggles, mask, gloves, gown
Explanation: Gloves are removed first (most contaminated), followed by eye protection, gown,
and finally mask/respirator to protect mucous membranes.
5. Standard Precautions apply to:
A. Only patients with diagnosed infections
,B. Only blood and body fluids with visible blood
C. All patients, all the time, regardless of diagnosis ✓
D. Only patients in isolation rooms
Explanation: Standard Precautions are the minimum infection prevention practices that apply to
all patient care, regardless of infection status.
6. A patient with Clostridioides difficile (C. diff) should be placed on:
A. Droplet Precautions
B. Contact Precautions ✓
C. Airborne Precautions
D. Standard Precautions only
Explanation: C. diff spores are spread via the fecal-oral route through contact with
contaminated surfaces or hands. Contact Precautions are required.
7. A patient with active pulmonary Tuberculosis requires:
A. Contact Precautions
B. Droplet Precautions
C. Airborne Infection Isolation Room (AIIR) ✓
D. Standard and Contact Precautions
Explanation: TB is transmitted via airborne droplet nuclei (small particles) that remain
suspended in air, requiring a negative pressure AIIR and N95 respirator.
8. The appropriate PPE for entering the room of a patient on Droplet Precautions for Influenza
is:
A. N95 respirator, gown, gloves
B. Surgical mask, gown, gloves ✓
C. N95 respirator only
D. Gown and gloves only
Explanation: Droplets are larger particles that don't remain suspended; a surgical mask is
sufficient. Gown/gloves are used based on anticipated contact.
9. An N95 respirator must be:
A. Used for all patients on isolation
B. Discarded after leaving any patient room
C. Reused for the same patient multiple times
D. Fit-tested for each individual wearer ✓
Explanation: N95s require an initial fit test to ensure a proper seal, and a user seal check each
time they are donned.
, 10. A needle safety device (engineered sharp) is an example of which level of the Hierarchy of
Controls?
A. Personal Protective Equipment (PPE)
B. Administrative Controls
C. Engineering Controls ✓
D. Elimination
Explanation: Engineering controls (like safer needle devices, sharps containers) physically
remove or isolate the hazard from the worker.
11. After a needlestick injury, the FIRST action is to:
A. Report to a supervisor
B. Complete an incident report
C. Wash the area with soap and water ✓
D. Go to the Emergency Department
Explanation: Immediate first aid is crucial: wash the wound with soap and water or flush
mucous membranes with water.
12. Multi-dose vials should be:
A. Used for one patient only
B. Dated when opened and discarded per facility policy ✓
C. Stored at the bedside for easy access
D. Used until empty, regardless of time
*Explanation: To prevent contamination, multi-dose vials must be labeled with the date of first
use and discarded within a specified time (e.g., 28 days).*
13. The primary purpose of a sterile field is to:
A. Organize equipment
B. Reduce the time of a procedure
C. Prevent microbial contamination of the surgical site ✓
D. Protect the healthcare worker
Explanation: A sterile field provides a microorganism-free area to protect the patient during
invasive procedures.
14. Surgical asepsis refers to:
A. Clean technique (e.g., bed bath)
B. The absence of all microorganisms in a defined area ✓
C. Reducing the number of microorganisms
D. The use of disinfectants only
