ONS ONCC CHEMOTHERAPY IMMUNOTHERAPY CERTIFICATION
LATEST 170 EXAM QUESTIONS 2026/2027 || ONCOLOGY NURSING
REVIEW || CHEMOTHERAPY & IMMUNOTHERAPY PRINCIPLES ||
VERIFIED QUESTIONS WITH ACCURATE ANSWERS || HIGH-YIELD
STUDY GUIDE || COMPLETE TEST BANK || GRADED A+
170 exam questions and answers
The stem cell divides, producing undifferentiated stem cells that are of what
lineage? - CORRECT ANSWER -myeloid or lymphoid
What cells do myeloid precursors turn into? - CORRECT ANSWER -red
blood cells, white blood cells, and platelets
What cells do lymphoid precursors turn into? - CORRECT ANSWER -
specialized white blood cells called lymphocytes
Granulocytes are - CORRECT ANSWER -basophils, eosinophils, neutrophils
Agranuloyctes are - CORRECT ANSWER -T lymphocytes, B lymphocytes,
monocytes
What two type of immunity make up the immune system? - CORRECT
ANSWER -innate and adaptive
What line of defense is innate immunity? - CORRECT ANSWER -first
What is the role of innate immunity? - CORRECT ANSWER -is to mount a
non-specific response to a non-self entity that does not retain memory of the
entity
What types of things does innate immunity respond to? - CORRECT
ANSWER -skin, mucous membranes, normal flora of the skin and gut as
,barrier or bacterial protection against foreign substances AND cellular
components such as phagocytes, natural killer cells, granulocytes, and
macrophages
If innate immunity proves to be insufficient, what is mobilized? - CORRECT
ANSWER -adaptive immunity
Adaptive immunity leads to what? - CORRECT ANSWER -immune system
memory related to a pathogen or foreign substance
What are the three parts of adaptive immunity? - CORRECT ANSWER -
humoral immunity, cell mediated immunity, regulatory t-cells
What is humoral immunity made up of? - CORRECT ANSWER -b
lymphocytes, memory b cells, and plasma to produce immunoglobulins or
antibodies
What is cell mediated immunity dependent on? - CORRECT ANSWER -
cytotoxic t-cells, helper t-cells and their cytokines
What are regulatory t-cells also known as? - CORRECT ANSWER -supressor
t-cells
What do regulatory t-cells do? - CORRECT ANSWER -regulate the immune
response to prevent autoimmune reactions and limit inflammatory responses
What are cytokines? - CORRECT ANSWER -cytokines are secreted by
lymphocytes with the intention of stimulating macrophages and cytotoxic t
lymphocytes to identify and kill pathogen infected cells or tumor cells
,What do proto-oncogenes do? - CORRECT ANSWER -regulate normal cell
growth and division.
What are proto-oncogenes? - CORRECT ANSWER -they are a large family of
genes that code for proteins and enzymes that turn on the cell cycle
If a mistake in copies of DNA occur next to a porto-oncogene, it can "turn on"
and become what? - CORRECT ANSWER -oncogene
What are two examples of an oncogene? - CORRECT ANSWER -EGFR/Erb-
B1 and Erb-B2/HER2
What is a very important tumor suppressor gene? - CORRECT ANSWER -
p53
What is the p53 gene also called? - CORRECT ANSWER -suicide gene
What does neoadjuvant therapy refer to? - CORRECT ANSWER -treatment
given as a first step to shrink a tumor before the main treatment
What is adjuvant therapy? - CORRECT ANSWER -additional cancer
treatment given after the primary treatment to lower the risk that cancer will
occur
How do alkylating agents function? - CORRECT ANSWER -by causing a
break in the DNA helix strand, causing interference with DNA replication,
which results in cell death
What are the three most common alkylating agent chemo's? - CORRECT
ANSWER -cytoxan, ifos, bendamustine
, How are alkylating agents and platinum based chemo's different? - CORRECT
ANSWER -platinum based chemo's do not have the molecule to to attach to
and destroy DNA
What are the two most common platinum based chemo's? - CORRECT
ANSWER -cisplatin and carboplatin
What should you instruct patients to do when receiving oxaliplatin? -
CORRECT ANSWER -to avoid exposure to cold air and consuming cold
fluids for 3 to 4 days following treatment
What are the two most nephrotoxic drugs? - CORRECT ANSWER -
streptozocin and semustine
What are the most common side effects of antimetabolites? - CORRECT
ANSWER -myelosuppresion, GI toxicities, photosensitivity, hand foot
syndrome,
What kind of chemo therapy require life time doses? - CORRECT ANSWER -
antitumor antibiotics
What are examples of anthracyclines that? - CORRECT ANSWER -
doxorubicin, daunarubicin, epirubicin, idarubicin
What are lifetime doses needed for anthrcyclines? - CORRECT ANSWER -
cardiotoxicity
What are classes of antitumor antibiotics? - CORRECT ANSWER -
anthracyclines and non-anthracyclines
LATEST 170 EXAM QUESTIONS 2026/2027 || ONCOLOGY NURSING
REVIEW || CHEMOTHERAPY & IMMUNOTHERAPY PRINCIPLES ||
VERIFIED QUESTIONS WITH ACCURATE ANSWERS || HIGH-YIELD
STUDY GUIDE || COMPLETE TEST BANK || GRADED A+
170 exam questions and answers
The stem cell divides, producing undifferentiated stem cells that are of what
lineage? - CORRECT ANSWER -myeloid or lymphoid
What cells do myeloid precursors turn into? - CORRECT ANSWER -red
blood cells, white blood cells, and platelets
What cells do lymphoid precursors turn into? - CORRECT ANSWER -
specialized white blood cells called lymphocytes
Granulocytes are - CORRECT ANSWER -basophils, eosinophils, neutrophils
Agranuloyctes are - CORRECT ANSWER -T lymphocytes, B lymphocytes,
monocytes
What two type of immunity make up the immune system? - CORRECT
ANSWER -innate and adaptive
What line of defense is innate immunity? - CORRECT ANSWER -first
What is the role of innate immunity? - CORRECT ANSWER -is to mount a
non-specific response to a non-self entity that does not retain memory of the
entity
What types of things does innate immunity respond to? - CORRECT
ANSWER -skin, mucous membranes, normal flora of the skin and gut as
,barrier or bacterial protection against foreign substances AND cellular
components such as phagocytes, natural killer cells, granulocytes, and
macrophages
If innate immunity proves to be insufficient, what is mobilized? - CORRECT
ANSWER -adaptive immunity
Adaptive immunity leads to what? - CORRECT ANSWER -immune system
memory related to a pathogen or foreign substance
What are the three parts of adaptive immunity? - CORRECT ANSWER -
humoral immunity, cell mediated immunity, regulatory t-cells
What is humoral immunity made up of? - CORRECT ANSWER -b
lymphocytes, memory b cells, and plasma to produce immunoglobulins or
antibodies
What is cell mediated immunity dependent on? - CORRECT ANSWER -
cytotoxic t-cells, helper t-cells and their cytokines
What are regulatory t-cells also known as? - CORRECT ANSWER -supressor
t-cells
What do regulatory t-cells do? - CORRECT ANSWER -regulate the immune
response to prevent autoimmune reactions and limit inflammatory responses
What are cytokines? - CORRECT ANSWER -cytokines are secreted by
lymphocytes with the intention of stimulating macrophages and cytotoxic t
lymphocytes to identify and kill pathogen infected cells or tumor cells
,What do proto-oncogenes do? - CORRECT ANSWER -regulate normal cell
growth and division.
What are proto-oncogenes? - CORRECT ANSWER -they are a large family of
genes that code for proteins and enzymes that turn on the cell cycle
If a mistake in copies of DNA occur next to a porto-oncogene, it can "turn on"
and become what? - CORRECT ANSWER -oncogene
What are two examples of an oncogene? - CORRECT ANSWER -EGFR/Erb-
B1 and Erb-B2/HER2
What is a very important tumor suppressor gene? - CORRECT ANSWER -
p53
What is the p53 gene also called? - CORRECT ANSWER -suicide gene
What does neoadjuvant therapy refer to? - CORRECT ANSWER -treatment
given as a first step to shrink a tumor before the main treatment
What is adjuvant therapy? - CORRECT ANSWER -additional cancer
treatment given after the primary treatment to lower the risk that cancer will
occur
How do alkylating agents function? - CORRECT ANSWER -by causing a
break in the DNA helix strand, causing interference with DNA replication,
which results in cell death
What are the three most common alkylating agent chemo's? - CORRECT
ANSWER -cytoxan, ifos, bendamustine
, How are alkylating agents and platinum based chemo's different? - CORRECT
ANSWER -platinum based chemo's do not have the molecule to to attach to
and destroy DNA
What are the two most common platinum based chemo's? - CORRECT
ANSWER -cisplatin and carboplatin
What should you instruct patients to do when receiving oxaliplatin? -
CORRECT ANSWER -to avoid exposure to cold air and consuming cold
fluids for 3 to 4 days following treatment
What are the two most nephrotoxic drugs? - CORRECT ANSWER -
streptozocin and semustine
What are the most common side effects of antimetabolites? - CORRECT
ANSWER -myelosuppresion, GI toxicities, photosensitivity, hand foot
syndrome,
What kind of chemo therapy require life time doses? - CORRECT ANSWER -
antitumor antibiotics
What are examples of anthracyclines that? - CORRECT ANSWER -
doxorubicin, daunarubicin, epirubicin, idarubicin
What are lifetime doses needed for anthrcyclines? - CORRECT ANSWER -
cardiotoxicity
What are classes of antitumor antibiotics? - CORRECT ANSWER -
anthracyclines and non-anthracyclines
