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Components of the Cardiovascular System ✔Correct Answer-- Heart
- Blood vessels
• arteries
• capillaries
• veins
- Blood
Hematology ✔Correct Answer-Is the study of blood and blood producing tissue.
Is blood a connective tissue? Does is differ from others? ✔Correct Answer-It is a connective tissue
that differs from the others because its matrix (plasma) is fluid, lacking fibers, not produced by the
tissue's cells.
How much blood does the average adult have? ✔Correct Answer-4-6 liters.
Blood Composition is made up of what? ✔Correct Answer-45% formed elements and 55% plasma.
Formed Elements ✔Correct Answer-= cells and cell fragments (45%)
What are the formed element types of blood? ✔Correct Answer-- Erythrocytes (RBC)
- Leukocytes (WBC)
- Thrombocytes (Platelets)
Erythrocytes (RBC) ✔Correct Answer-Transport oxygen gas.
Leukocytes (WBC) ✔Correct Answer-Protect against infection.
Thrombocytes (Platelets) ✔Correct Answer-Cell fragments that prevent blood loss.
What is Hematopoiesis? ✔Correct Answer-It is the production of blood cells.
Erythropoiesis ✔Correct Answer-production of red blood cells.
Leukopoiesis ✔Correct Answer-production of white blood cells.
Thrombopoiesis ✔Correct Answer-production of platelets.
Where are cells produced in blood composition? ✔Correct Answer-They are reproduced in red
bone marrow from hematopoietic stem cells.
Plasma ✔Correct Answer-= Fluid component (55%).
Plasma composition percentages ✔Correct Answer-- plasma proteins 7%
- other solutions 1%
, - water 92%
Plasma proteins ✔Correct Answer-- albumins
- globulins
- fibrinogen
Albumins ✔Correct Answer-osmotic pressure.
Globulins ✔Correct Answer-Antibodies and transport.
Fibrinogen ✔Correct Answer-Coagulation.
Red blood cells SHAPE ✔Correct Answer-biconcave disk.
Do RBCs have a nucleus? ✔Correct Answer-They have no nucleus.
How many RBC's per microliter of blood? ✔Correct Answer-5.2 million/mm3
Biconcave disks (RBC) ✔Correct Answer-- high surface area to volume ratio
- all cytoplasm is near the plasma membrane
- smooth and flexible
- able to form stacks that slide through small capillaries
Functional Aspects of RBCs ✔Correct Answer-- Large surface area-to-volume ratio
- RBCs can form stacks
- Flexibility
Anemia ✔Correct Answer-Any condition in which ability of the blood to transport oxygen gas is
diminished.
Hemoglobin Terms ✔Correct Answer-- Oxyhemoglobin (bright red)
- Deoxyhemoglobin (dark red)
Hemoglobin Structure ✔Correct Answer-- 4 polypeptides
• 2 alpha chains
• 2 beta chains
- 4 heme groups containing iron
Heme ✔Correct Answer-iron-based, pigment part of hemoglobin.
Sickle Cell Anemia ✔Correct Answer-The change in amino acid sequence causes hemoglobin
molecules to crystalize when oxygen levels in the blood are low. As a result, red blood cells sickle and
get stuck in small blood vessels.
RBC LIFE CYCLE ✔Correct Answer-- low blood O2 stimulates liver and kidneys to secrete
erythropoietin which targets red bone marrow and promotes erythropoiesis.
- After about 120 days, damaged or worn RBC are destroyed as they pass through the spleen and
liver.
- Macrophages (WBCs) phagocytize the remains.