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Lecture notes of 16 pages for the course Comparative & Integrative physiology at QMUL

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Water and salt (ion) physiology
Water

Function of water in the body

 Water is essential for life
 No water = no reactions will take place
 Cell life
- Participates in chemical and metabolic reactions
- Transports nutrients
 Body temperature regulation
 Elimination of waste
 Lubricant joints
 Our senses rely on water
- i.e. eyes, ears, mouth, nose
 commonly known as universal solvent
- water is a solvent
 polarity allows it to attract charged particles into solutions and dissolve a variety of other polar substances
- important to digestion
 helps transport dissolved nutrients and other substances throughout the body
- water allows blood to transport oxygen, nutrients and hormones to cells
- water helps transport waste products away from cells to be excreted



Dissolved substances

 Ions




 Glucose

,Water helps regulate body temperate




Function of water

 Water is essential for most chemical reaction in the body
- During digestion water hydrolyses the bonds holding together
Carbohydrate molecules
Protein molecules
Fat molecules




- When smaller molecules combine together through condensation water is formed

, Daily water requirements

 Based on metabolic rate
- Take 80-110 mls/100kcal
 Based on body surface area
- Take 1.5 I/m2/day
 Based on weight
- Take 30 – 40 mls/kg/day
 Essentially saying how much water is needed to replace these activities

Water is dynamic

 Water is dynamic and can change depending on many factors and therefore needs to be regulated
- Loosing too much water = bad for us
- Drinking too much water = bad for us
 Fluid homeostasis
 Lose water by excretion and sweating therefore we drink water for rapid turnover
 Adapt to changing environment
 Amount consumed= amount excreted

Water excretion

 Majority of fluid is excreted through the kidneys
- The more water that is ingested the more urine produced
 Excreted through intestinal fluids in the stool
- Dependant on dietary intake of plant fibers and presents of diarrhoea
 Evaporated through exhalation and through the skin
- Insensible water loss
 Loss through sweat
- Varied based on environmental factors
Temperature
Humidity
Wind – causes dry skin and increases rate of evaporation
Sun’s intensity
Clothing – over heat and sweat
- Amount of physical activity

Daily obligatory water loss

 Minimal amount of fluid loss
- Insensible loss
- 800 ml
 Minimal sweat loss
- 100 ml
 Faecal loss
- 200 ml
- More if have diarrhoea
 Minimal urine volume to excrete solute load
- 500 ml
 Total = 1,600 ml

Electrolytes participate in body fluid composition

 Electrolytes (salts) vital in diet
- Minerals with electrically charged ions
Potassium
Phosphate
Magnesium
Calcium
Chloride

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Uploaded on
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Number of pages
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