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Psychopharmacology,ThirdEdition s
Meyer • Quenzer ss ss
Chapter 1: Principles of Pharmacology ss ss ss ss
Multiple Choice ss
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to a particular target site or receptor, while are the resulting widespread
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alterations in function.
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a. Drug action; therapeutic effects
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b. Side effects; drug effects
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c. Therapeutic effects; side effects ss ss ss
d. Drug action; drug effects
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Answer: d ss
Textbook Reference: Pharmacology: The Science of Drug Action
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2. After drug administration has occurred, the amount of drug in the blood that is
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free tobind at specific target sites is referred to as
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a. the therapeutic dose.
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b. first-pass effects. ss
c. bioavailability.
d. ED50.
Answer: c ss
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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3. The specific molecular changes that occur when a drug binds to a particular
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target site or receptor are referred to as
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a. drug effects. ss
b. drug action. ss
c. side effects. s
d. placebo effects. ss
Answer: b ss
Textbook Reference: Pharmacology: The Science of Drug Action
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4. Which of the following is not a possible explanation for placebo effects?
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a. Pavlovian conditioning ss
b. Genetic variation ss
c. Drug competition ss
d. Expectation of outcome ss ss
Answer: c ss
Textbook Reference: Pharmacology: The Science of Drug Action
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Page 1 of 247
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Psychopharmacology Drugs the Brain And Behavior 3 jj jj jj jj jj jj s s
Edition meyer Nursing
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Test Bank
5. The administration of oxytocin has been proposed as a treatment for autism. ss ss ss ss ss ss ss ss ss ss
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: c ss
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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6. Which factor does not affect the pharmacokinetics of a drug?
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a. Route of administrationss ss
b. Lipid solubility ss
c. Depot binding ss
d. Drug action ss
Answer: d ss
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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7. First-pass metabolism occurs when drugs are takenss ss ss ss ss ss
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: a ss
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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8. The area postrema is one area in the brain where the
ss ss is not complete. ss ss ss ss ss ss ss ss ss ss
a. cerebrospinal fluid ss
b. blood–brain barrier ss
c. choroid plexus ss
d. phospholipid membrane ss
Answer: b ss
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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9. First-pass metabolism occurs with orally administered drugs because
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a. their absorption is slowed by food.
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b. drugs absorbed into the bloodstream from the stomach go to the liver on the
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way togeneral circulation.
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c. drugs must first survive the acidic environment of the stomach.
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d. salivary enzymes in the mouth begin the process of metabolism.
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Answer: b ss
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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10. Toxic substances in the blood trigger a vomiting response by activating the
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a. blood–brain barrier. ss
b. choroid plexus. ss
c. area postrema.
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d. median eminence. ss
Page 2 of 247
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Psychopharmacology Drugs the Brain And Behavior 3 jj jj jj jj jj jj s s
Edition meyer Nursing
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Test Bank
Answer: c ss
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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11. Drugs administered _ have the most rapid onset of action.
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a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: d ss
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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12. Ionization of a drug depends on the of the solution and the
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thedrug.
ss
a. pH; pKa ss
b. pKa; pH ss
c. concentration; lipid solubility ss ss
d. pH; concentration
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Answer: a ss
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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13. The absorption of a drug depends on all of the following except
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a. lipid solubility.
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b. ionization.
c. body temperature.
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d. the concentration of the drug.
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Answer: c ss
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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14. Drugs that are should be avoided by women of childbearing age.
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a. teratogenic
b. able to cross the placental barrier
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c. psychoactive
d. highly lipid-soluble ss
Answer: a ss
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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15. Agents that induce developmental abnormalities in a fetus are known as
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a. psychoactive drugs. ss
b. illicit drugs. ss
c. teratogens.
d. placental drugs. ss
Answer: c ss
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
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16. Depot binding is said to occur when drugs
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a. bind to their target sites.
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Page 3 of 247
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Test Bank
jj jj
, rd
Psychopharmacology Drugs the Brain And Behavior 3 jj jj jj jj jj jj s s
Edition meyer Nursing
s s jj jj jj
Test Bank
Test Bank ss
to accompanyss
Psychopharmacology,ThirdEdition s
Meyer • Quenzer ss ss
Chapter 1: Principles of Pharmacology ss ss ss ss
Multiple Choice ss
1. refer(s) to specific molecular changes that occur when a drug binds ss ss ss ss ss ss ss ss ss ss
to a particular target site or receptor, while are the resulting widespread
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alterations in function.
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a. Drug action; therapeutic effects
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b. Side effects; drug effects
ss ss ss
c. Therapeutic effects; side effects ss ss ss
d. Drug action; drug effects
ss ss ss
Answer: d ss
Textbook Reference: Pharmacology: The Science of Drug Action
ss ss ss ss ss ss ss
2. After drug administration has occurred, the amount of drug in the blood that is
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free tobind at specific target sites is referred to as
ss ss ss ss ss ss ss ss ss ss
a. the therapeutic dose.
ss ss
b. first-pass effects. ss
c. bioavailability.
d. ED50.
Answer: c ss
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ss ss ss ss ss ss
3. The specific molecular changes that occur when a drug binds to a particular
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target site or receptor are referred to as
ss ss jj ss ss ss ss ss
a. drug effects. ss
b. drug action. ss
c. side effects. s
d. placebo effects. ss
Answer: b ss
Textbook Reference: Pharmacology: The Science of Drug Action
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4. Which of the following is not a possible explanation for placebo effects?
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a. Pavlovian conditioning ss
b. Genetic variation ss
c. Drug competition ss
d. Expectation of outcome ss ss
Answer: c ss
Textbook Reference: Pharmacology: The Science of Drug Action
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Page 1 of 247
ss ss ss
, rd
Psychopharmacology Drugs the Brain And Behavior 3 jj jj jj jj jj jj s s
Edition meyer Nursing
s s jj jj jj
Test Bank
5. The administration of oxytocin has been proposed as a treatment for autism. ss ss ss ss ss ss ss ss ss ss
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: c ss
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ss ss ss ss ss ss
6. Which factor does not affect the pharmacokinetics of a drug?
ss ss ss ss ss ss ss ss ss
a. Route of administrationss ss
b. Lipid solubility ss
c. Depot binding ss
d. Drug action ss
Answer: d ss
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ss ss ss ss ss ss
7. First-pass metabolism occurs when drugs are takenss ss ss ss ss ss
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: a ss
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ss ss ss ss ss ss
8. The area postrema is one area in the brain where the
ss ss is not complete. ss ss ss ss ss ss ss ss ss ss
a. cerebrospinal fluid ss
b. blood–brain barrier ss
c. choroid plexus ss
d. phospholipid membrane ss
Answer: b ss
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ss ss ss ss ss ss
9. First-pass metabolism occurs with orally administered drugs because
ss ss ss ss ss ss ss
a. their absorption is slowed by food.
ss ss ss ss ss
b. drugs absorbed into the bloodstream from the stomach go to the liver on the
ss ss ss ss ss ss ss ss ss ss ss ss ss
way togeneral circulation.
ss ss ss
c. drugs must first survive the acidic environment of the stomach.
ss ss ss ss ss ss ss ss ss
d. salivary enzymes in the mouth begin the process of metabolism.
ss ss ss ss ss ss ss ss ss
Answer: b ss
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ss ss ss ss ss ss
10. Toxic substances in the blood trigger a vomiting response by activating the
ss ss ss ss ss ss ss ss ss ss ss
a. blood–brain barrier. ss
b. choroid plexus. ss
c. area postrema.
ss
d. median eminence. ss
Page 2 of 247
ss ss ss
, rd
Psychopharmacology Drugs the Brain And Behavior 3 jj jj jj jj jj jj s s
Edition meyer Nursing
s s jj jj jj
Test Bank
Answer: c ss
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ss ss ss ss ss ss
11. Drugs administered _ have the most rapid onset of action.
ss ss ss ss ss ss ss ss
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: d ss
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ss ss ss ss ss ss
12. Ionization of a drug depends on the of the solution and the
ss ss ss ss ss ss ss ss ss ss of
thedrug.
ss
a. pH; pKa ss
b. pKa; pH ss
c. concentration; lipid solubility ss ss
d. pH; concentration
ss
Answer: a ss
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ss ss ss ss ss ss
13. The absorption of a drug depends on all of the following except
ss ss ss ss ss ss ss ss ss ss ss
a. lipid solubility.
ss
b. ionization.
c. body temperature.
ss
d. the concentration of the drug.
ss ss ss ss
Answer: c ss
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ss ss ss ss ss ss
14. Drugs that are should be avoided by women of childbearing age.
ss ss ss ss ss ss ss ss ss
a. teratogenic
b. able to cross the placental barrier
ss ss ss ss ss
c. psychoactive
d. highly lipid-soluble ss
Answer: a ss
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ss ss ss ss ss ss
15. Agents that induce developmental abnormalities in a fetus are known as
ss ss ss ss ss ss ss ss ss ss
a. psychoactive drugs. ss
b. illicit drugs. ss
c. teratogens.
d. placental drugs. ss
Answer: c ss
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ss ss ss ss ss ss
16. Depot binding is said to occur when drugs
ss ss ss ss ss ss ss
a. bind to their target sites.
ss ss ss ss
Page 3 of 247
ss ss ss
