Week 2 Part 1, 2 & 3
Discussion Responses
Respiratory Disorders and Alterations in Acid/Base
Balance,Fluid and Electrolytes
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Week 2: Respiratory Disorders and Alterations in Acid/Base Balance,
Fluid and Electrolytes - Discussion Part One
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This week's graded topics relate to the following Course Outcomes (COs).
Analyze pathophysiologic mechanisms associated with selected
disease states. (PO 1)
Differentiate the epidemiology, etiology, developmental
considerations, pathogenesis, and clinical and laboratory
manifestations of specific disease processes. (PO 1)
Examine the way in which homeostatic, adaptive, and compensatory
physiological mechanisms can be supported and/or altered through
specific therapeutic interventions. (PO 1, 7)
Distinguish risk factors associated with selected disease states. (PO
1)
Describe outcomes of disruptive or alterations in specific physiologic
processes. (PO 1)
Distinguish risk factors associated with selected disease states. (PO
1)
Explore age-specific and developmental alterations in physiologic
and disease states. (PO 1, 4)
Discussion Part One (graded)
A five-month-old Caucasian female is brought into the clinic as the parent complain that she has
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been having ongoing foul-smelling , greasy diarrhea. She seems to be small for her age and a
bit sickly but, her parent’s state that she has a huge appetite. Upon examination you find that
the patient is wheezing and you observe her coughing.
Write a differential diagnosis of at least five (5) disorders and explain why each might be
a possibility and any potential weaknesses of each differential.
Why is it that the later in age this disease manifest itself, the less severe the disease is?
What tests would you run to clarify your differential and potentially come to a definitive
diagnosis?
If the same child was African in ancestry would this change your initial differential? Why
or why not?
Responses
Liberty Neoh 5/8/2016 7:30:59 PM
Discussion Part One
Dr. Brown and Class,
1.) Write a differential diagnosis of at least five (5) disorders and explain why each might be a possibility and
any potential weaknesses of each differential.
Cystic Fibrosis (CF) is an autosomal-recessive disease of exocrine gland function involving
multiple organs and characterized by chronic respiratory infections, pancreatic enzymes
insufficiency, elevated chloride concentration in sweat and chronic obstructive pulmonary
disease (COPD) (Lewis, 2016). It is the most common inherited disease in Caucasians. 1 in
3,000 Caucasian children are born with CF.I chose CF as my number one differentials due to
the baby’s health history and symptoms: Caucasian, foul-smelling greasy diarrhea, small
feature even though the parents stated that “she has a huge appetite”, wheezing, and
coughing.
Lewis (2016) listed the following symptoms that are associated with CF:
Chronic cough, chronic sputum production, nasal polyps, chronic sinusitis, persistent
chest x-ray abnormalities, colonization with known CF pathogens such as, Pseudomonas
aeruginosa and Staphylococcus aureus. There are also pancreatic insufficiency, pancreatitis,
biliary cirrhosis, malnutrition, vitamin deficiency, greasy stools, frequent abdominal pain,
cramping with constipation, or obstruction, gastroesophageal reflux disease or GERD present
(Lewis, 2016).
Celiac Disease (CD) is an immune-mediated systemic disorder triggered by gluten-containing
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5/16/2016 10:48 PM