COMLEX Level 1 TrueLearn COMBank.
Newest 2026-2027. Questions &
Correct Answers. Graded A
"Eggshell" Calcification of hilar lymph nodes
Hx of working in sandblasting, foundries, or mines
Does not have productive cough - ANSSilicosis
2 yo M
developmental delay
SOB
Pulmonary vascular congestion, pulmonary edema
Renal angiomyolipomas
Small, nodular, soft tissue densities near nasolabial folds (cutaneous
angiofibromas) (Adenoma sebaceum)
1
,Cardiac rhabdomyoma (intracardiac soft tissue mass) - ANSTuberous
sclerosis
2-micron spherical micro-organisms in the brush border -
ANSCryptosporidiosis
24-hr urine shows vanillylmandelic acid and metanephrine -
ANSPheochromocytoma
- Tx: Phenoxybenzamine (nonselective irreversible alpha-blocker) &
surgical removal
4-6 micron single-cell organisms in the lumen near the absorptive surface
Purple burps
Belching w/ a sulfurous taste - ANSGiardiasis
40 yo F
Pruritus, jaundice, dark urine, light stools, hepatosplenomegaly
ERCP/MRCP normal w/ no extrahepatic biliary involvement
Associated w/ lymphocytic infiltration and biliary granulomas - ANSPrimary
biliary cirrhosis (PBC)
2
,- Tx. ursodeoxycholic acid, w/ liver transplant being the definitive tx in pt. w/
cirrhosis
58 yo M w/ fever, fatigue, body aches, generalized weakness, tender
erythematous rash on legs, abd pain, weight loss, dec. sensation in left
foot, BP 152/98 mmHg - ANSPolyarteritis nodosa (PAN)
- Hept B association
- Tx w/ high-dose corticosteroids and/or cyclophosphamide
59 yo F
Gradual muscle weakness, dizziness, hyperpigmented skin
Decreased serum Na, Cl, cortisol
Increased serum K and ACTH - ANSAddison's disease
- primary deficiency of aldosterone and cortisol
60 yo M w/ 1 month cough, fatigue, constipation. Blood-tinged sputum
(hemoptysis) over the last 2 weeks. No travel hx, no sick contact. 45-pack-
year cigarette smoking. Imaging reveals large, centrally located mass w/
cavitation and mildly enlarged mediastinal lymph nodes. Hypercalcemia. -
ANSSquamous cell carcinoma (SCC) of the lung
A condition of severe hypothyroidism
3
, Multisystem slowing - decreased mental status, hypothermia, bradycardia,
low cardiac output, hypoventilation, hyponatremia, and hypoglycemia
Medical emergency
Nonpitting edema
Abnormal albumin and mucin deposits in the skin and other tissues -
ANSMyxedema coma
A tall pt. w/ Fx of adrenal tumor, hx of multiple sprains, mucosal neuromas,
nontender thyroid nodule - ANSMultiple endocrine neoplasia syndrome
type 2B (MEN 2B)
- Tall stature and multiple sprains indicates Marfanoid appearance
- Nontender thyroid nodule is MTC
- Adrenal tumor = pheochromocytoma
Abd pain, dysuria, increased urinary frequency, hematuria, abnormal UA -
ANSUTI
Abd pain, weight loss, gallstones, diabetes, diarrhea
Increased somatostatin (> 30 pg/mL) - ANSSomatostatinoma
4
Newest 2026-2027. Questions &
Correct Answers. Graded A
"Eggshell" Calcification of hilar lymph nodes
Hx of working in sandblasting, foundries, or mines
Does not have productive cough - ANSSilicosis
2 yo M
developmental delay
SOB
Pulmonary vascular congestion, pulmonary edema
Renal angiomyolipomas
Small, nodular, soft tissue densities near nasolabial folds (cutaneous
angiofibromas) (Adenoma sebaceum)
1
,Cardiac rhabdomyoma (intracardiac soft tissue mass) - ANSTuberous
sclerosis
2-micron spherical micro-organisms in the brush border -
ANSCryptosporidiosis
24-hr urine shows vanillylmandelic acid and metanephrine -
ANSPheochromocytoma
- Tx: Phenoxybenzamine (nonselective irreversible alpha-blocker) &
surgical removal
4-6 micron single-cell organisms in the lumen near the absorptive surface
Purple burps
Belching w/ a sulfurous taste - ANSGiardiasis
40 yo F
Pruritus, jaundice, dark urine, light stools, hepatosplenomegaly
ERCP/MRCP normal w/ no extrahepatic biliary involvement
Associated w/ lymphocytic infiltration and biliary granulomas - ANSPrimary
biliary cirrhosis (PBC)
2
,- Tx. ursodeoxycholic acid, w/ liver transplant being the definitive tx in pt. w/
cirrhosis
58 yo M w/ fever, fatigue, body aches, generalized weakness, tender
erythematous rash on legs, abd pain, weight loss, dec. sensation in left
foot, BP 152/98 mmHg - ANSPolyarteritis nodosa (PAN)
- Hept B association
- Tx w/ high-dose corticosteroids and/or cyclophosphamide
59 yo F
Gradual muscle weakness, dizziness, hyperpigmented skin
Decreased serum Na, Cl, cortisol
Increased serum K and ACTH - ANSAddison's disease
- primary deficiency of aldosterone and cortisol
60 yo M w/ 1 month cough, fatigue, constipation. Blood-tinged sputum
(hemoptysis) over the last 2 weeks. No travel hx, no sick contact. 45-pack-
year cigarette smoking. Imaging reveals large, centrally located mass w/
cavitation and mildly enlarged mediastinal lymph nodes. Hypercalcemia. -
ANSSquamous cell carcinoma (SCC) of the lung
A condition of severe hypothyroidism
3
, Multisystem slowing - decreased mental status, hypothermia, bradycardia,
low cardiac output, hypoventilation, hyponatremia, and hypoglycemia
Medical emergency
Nonpitting edema
Abnormal albumin and mucin deposits in the skin and other tissues -
ANSMyxedema coma
A tall pt. w/ Fx of adrenal tumor, hx of multiple sprains, mucosal neuromas,
nontender thyroid nodule - ANSMultiple endocrine neoplasia syndrome
type 2B (MEN 2B)
- Tall stature and multiple sprains indicates Marfanoid appearance
- Nontender thyroid nodule is MTC
- Adrenal tumor = pheochromocytoma
Abd pain, dysuria, increased urinary frequency, hematuria, abnormal UA -
ANSUTI
Abd pain, weight loss, gallstones, diabetes, diarrhea
Increased somatostatin (> 30 pg/mL) - ANSSomatostatinoma
4
