CMN 548 UNIT 5 EXAM(ACTUAL EXAM)
WITH CORRECT ACTUAL QUESTIONS AND
CORRECTLY WELL DEFINED ANSWERS
LATEST ALREADY GRADED A+ 2026
What are the FDA recommendations for monitoring pts who
are prescribed SGAs? - ANSWERS--personal family hx of
obesity, diabetes, dyslipidemia, HTN, and cardiovascular
disease
-weight & height
-waist circumference (@ the level of the umbilicus)
-BP
-Fasting plasma glucose level
-fasting lipid profile
*pts with preexisting diabetes should have regular
monitoring, including hemoglobin A1C (HGA1c) and in some
cases insulin levels
,Which 2 SGAs responsible for the most cases of weight gain
and the development of diabetes? - ANSWERS-Olanzapine
and Clozapine
What are the therapeutic indications for the use of SGAs? -
ANSWERS-All SGAs are indicated for tx of schizophrenia.
Most SGAs have also received approval as monotherapy or
adjunctive therapy in the tx of bipolar d/o. Some have also
been approved as adjuncts of major depression.
What is the black box warning for SDAs regarding use in
elderly dementia patients? - ANSWERS-elderly persons with
dementia-related psychosis are at increased risk (1.6-1.7
times) of death compared with placebo
What are the benefits of tx with SDAs compared to DRAs for
pts with schizophrenia or schizoaffective d/o? - ANSWERS-
persons treated with SDAs have fewer relapses and require
less frequent hospitalization, fewer ED visits, less phone
contact with mental health professionals, and less tx and
day programs
Review the SDAs that are approved for the tx of acute
mania, bipolar d/o (monotherapy or adjunctive), and acute
,tx resistant depression? - ANSWERS-All of the SDAs (except
clozapine) are FDA approved for the tx of acute mania
-some of the agents, including aripiprazole, olanzapine,
quetiapine, and quetiapine XR are also approved for the
maintenance tx in BIPOLAR D/O as monotherapy or
adjunctive therapy.
-Olanzapine in combo with fluoxetine has been approved
for tx resistant depression, and aripiprazole and quetiapine
XR are indicated for adjunctive therapy to antidepressants
in MDD.
-Quetiapine and Quetiapine XR are also approved for
bipolar depression. A fixed combo of olanzapine and
fluoxetine is approved for tx of acute bipolar depression
Review off label uses for SDAs? - ANSWERS-Aggression or
violence in pts with schizophrenia, AIDS, dementia, autistic
spectrum d/o, tourette's d/o, huntingtons disease, lesch-
nyhan syndrome, ADHD comorbid with ODD or conduct d/o
when co-administered with sympathomimetics, severe
tardive dyskinesia, psychotic depression, andfor psychosis
secondary to head trauma, dementia or tx drugs
Risperidone (Risperdal)-what are the indications for use?
What is the difference between risperidone and haloperidol
with respect to EPS? What are the most common reasons
, for discontinuation of risperidone? - ANSWERS-indications:
acute and maintenance treatment of schizophrenia in adults
and for the tx of schizophrenia in adolescents age 13 to 17.
Also indicated for short term tx in acute manic or mixed
episodes associated w/bipolar I d/o in adults and children
and adolescents age 10 to 17. Combination of risperidone
with lithium or valproate is indicated for the short term tx of
manic or mixed episodes of bipolar I d/o. Risperidone is also
indicated for the tx of irritability associated with autistic
spectrum d/o in children and adolescents age 5-16 yrs,
including s/s of aggression toward others, deliberate self
injuriousness, temper tantrums, and quick changing moods.
*risperidone is much less likely than haloperidol to cause
EPS in humans when the dose of risperidone is below 6mg
per day
*The most common drug related reasons for
discontinuation of risperidone use are EPS, dizziness,
hyperkinesias, somnolence, and nausea
Paliperidone (Invega)-indications? what are the
recommendations for initiating and maintaining Invega
Sustenna? What are the SE regarding temperature
sensitivity and potential cardiac complications? - ANSWERS-
WITH CORRECT ACTUAL QUESTIONS AND
CORRECTLY WELL DEFINED ANSWERS
LATEST ALREADY GRADED A+ 2026
What are the FDA recommendations for monitoring pts who
are prescribed SGAs? - ANSWERS--personal family hx of
obesity, diabetes, dyslipidemia, HTN, and cardiovascular
disease
-weight & height
-waist circumference (@ the level of the umbilicus)
-BP
-Fasting plasma glucose level
-fasting lipid profile
*pts with preexisting diabetes should have regular
monitoring, including hemoglobin A1C (HGA1c) and in some
cases insulin levels
,Which 2 SGAs responsible for the most cases of weight gain
and the development of diabetes? - ANSWERS-Olanzapine
and Clozapine
What are the therapeutic indications for the use of SGAs? -
ANSWERS-All SGAs are indicated for tx of schizophrenia.
Most SGAs have also received approval as monotherapy or
adjunctive therapy in the tx of bipolar d/o. Some have also
been approved as adjuncts of major depression.
What is the black box warning for SDAs regarding use in
elderly dementia patients? - ANSWERS-elderly persons with
dementia-related psychosis are at increased risk (1.6-1.7
times) of death compared with placebo
What are the benefits of tx with SDAs compared to DRAs for
pts with schizophrenia or schizoaffective d/o? - ANSWERS-
persons treated with SDAs have fewer relapses and require
less frequent hospitalization, fewer ED visits, less phone
contact with mental health professionals, and less tx and
day programs
Review the SDAs that are approved for the tx of acute
mania, bipolar d/o (monotherapy or adjunctive), and acute
,tx resistant depression? - ANSWERS-All of the SDAs (except
clozapine) are FDA approved for the tx of acute mania
-some of the agents, including aripiprazole, olanzapine,
quetiapine, and quetiapine XR are also approved for the
maintenance tx in BIPOLAR D/O as monotherapy or
adjunctive therapy.
-Olanzapine in combo with fluoxetine has been approved
for tx resistant depression, and aripiprazole and quetiapine
XR are indicated for adjunctive therapy to antidepressants
in MDD.
-Quetiapine and Quetiapine XR are also approved for
bipolar depression. A fixed combo of olanzapine and
fluoxetine is approved for tx of acute bipolar depression
Review off label uses for SDAs? - ANSWERS-Aggression or
violence in pts with schizophrenia, AIDS, dementia, autistic
spectrum d/o, tourette's d/o, huntingtons disease, lesch-
nyhan syndrome, ADHD comorbid with ODD or conduct d/o
when co-administered with sympathomimetics, severe
tardive dyskinesia, psychotic depression, andfor psychosis
secondary to head trauma, dementia or tx drugs
Risperidone (Risperdal)-what are the indications for use?
What is the difference between risperidone and haloperidol
with respect to EPS? What are the most common reasons
, for discontinuation of risperidone? - ANSWERS-indications:
acute and maintenance treatment of schizophrenia in adults
and for the tx of schizophrenia in adolescents age 13 to 17.
Also indicated for short term tx in acute manic or mixed
episodes associated w/bipolar I d/o in adults and children
and adolescents age 10 to 17. Combination of risperidone
with lithium or valproate is indicated for the short term tx of
manic or mixed episodes of bipolar I d/o. Risperidone is also
indicated for the tx of irritability associated with autistic
spectrum d/o in children and adolescents age 5-16 yrs,
including s/s of aggression toward others, deliberate self
injuriousness, temper tantrums, and quick changing moods.
*risperidone is much less likely than haloperidol to cause
EPS in humans when the dose of risperidone is below 6mg
per day
*The most common drug related reasons for
discontinuation of risperidone use are EPS, dizziness,
hyperkinesias, somnolence, and nausea
Paliperidone (Invega)-indications? what are the
recommendations for initiating and maintaining Invega
Sustenna? What are the SE regarding temperature
sensitivity and potential cardiac complications? - ANSWERS-
