NUR 210, 242
EXAM 4 STUDY GUIDE
Pharmacology and Medsurge
Galen College of Nursing
,
, Exam 4
Intro to antibiotics
Antibacterial & Antimicrobials
Inhibit bacterial growth or kill the bacteria and microorganisms
Antibacterial drugs may be used with other mechanisms to eliminate the infecting
bacteria. For example, surgical procedures, dressing changes may also be performed along w/
the administration of an antibacterial agent
Antibiotics
Chemical produced by one kind of microorganisms that inhibit or kill another
Antibacterials and antibacterial drugs
Antibacterials have the help of the bodys natural defenses that help kill the bacteria as
well
Factors that impact immune function are:
Age
Nutrition
Immunoglobulins
Circulation, WBCs
Organ function
Antibacterial drugs have a different mechanism of action
Inhibition of bacterial cell wall synthesis
Alteration of membrane permeability
Inhibition of protein synthesis
Inhibition of synthesis of bacterial RNA and DNA
Interference with metabolism within the cell
Indications for antibiotics
Prophylactic use
Pts undergoing surgery
STI exposure
Prior to dental/procedures for pts at risk for prosthetic infection (heart valve, hip
replacement)
Recurrent UTIs
Antibiotic mild allergic reaction
Rash, pruritus, hives
Antibiotic severe allergy: anaphylactic shock
Bronchospasm, laryngeal edema, difficulty breathing, vascular collapse, cardiac arrest
(emergency-stop antibiotic immediately)
Antibiotic superinfection
Secondary infection that occurs due to the unbalanced normal flora in the body.
Antibiotics disrupt the normal microbial flora that is in the body
Usually occurs with longer antibiotic therapy
Mouth respiratory tract, intestine, genitourinary tract, and skin
Symptoms: stomatitis (mouth ulcers), genital discharge, anal, or genital itching, thrush.
Prevent by restoring normal flora- buttermilk, yogurt, probiotics
Antibiotics organ toxicity
EXAM 4 STUDY GUIDE
Pharmacology and Medsurge
Galen College of Nursing
,
, Exam 4
Intro to antibiotics
Antibacterial & Antimicrobials
Inhibit bacterial growth or kill the bacteria and microorganisms
Antibacterial drugs may be used with other mechanisms to eliminate the infecting
bacteria. For example, surgical procedures, dressing changes may also be performed along w/
the administration of an antibacterial agent
Antibiotics
Chemical produced by one kind of microorganisms that inhibit or kill another
Antibacterials and antibacterial drugs
Antibacterials have the help of the bodys natural defenses that help kill the bacteria as
well
Factors that impact immune function are:
Age
Nutrition
Immunoglobulins
Circulation, WBCs
Organ function
Antibacterial drugs have a different mechanism of action
Inhibition of bacterial cell wall synthesis
Alteration of membrane permeability
Inhibition of protein synthesis
Inhibition of synthesis of bacterial RNA and DNA
Interference with metabolism within the cell
Indications for antibiotics
Prophylactic use
Pts undergoing surgery
STI exposure
Prior to dental/procedures for pts at risk for prosthetic infection (heart valve, hip
replacement)
Recurrent UTIs
Antibiotic mild allergic reaction
Rash, pruritus, hives
Antibiotic severe allergy: anaphylactic shock
Bronchospasm, laryngeal edema, difficulty breathing, vascular collapse, cardiac arrest
(emergency-stop antibiotic immediately)
Antibiotic superinfection
Secondary infection that occurs due to the unbalanced normal flora in the body.
Antibiotics disrupt the normal microbial flora that is in the body
Usually occurs with longer antibiotic therapy
Mouth respiratory tract, intestine, genitourinary tract, and skin
Symptoms: stomatitis (mouth ulcers), genital discharge, anal, or genital itching, thrush.
Prevent by restoring normal flora- buttermilk, yogurt, probiotics
Antibiotics organ toxicity
