NURS 660 EXAM 3
What is the medication that is the antidote for alprazolam? - Answer-flumazenil
What is the MOA of pregabalin that makes it alleviate pain for people with fibromyalgia or chronic
fatigue? - Answer-binds to the alpha 2 delta sub-units of voltage sensitive calcium channels
What is an antagonist of caffeine - Answer-adenosine
Diagnose this pt: Patient comes in with a CC of anxiety. She has been excessively worrying, increased
arousal, increased tiredness and irritability. What is the primary and least likely diagnosis? - Answer-
GAD; Panic Disorder
Somebody w/ anxiety worries about having a panic attack, in addition has mood changes to avoid things
in order to not have a panic attack. - Answer-Panic disorder
A woman was raped, and continues to have fear of opposite sex on her way to parking garage. Which
two areas of the brain are involved? - Answer-amygdala and hippocampus
MOA of modafinil (Provigil). How does it promote normal wakefulness - Answer-histamine, NE at alpha
adrenergic receptor sites, dopamine at D2 receptors
What is the MOA of eszopiclone? What receptors does it act on? - Answer-Binds to GABA receptors to
increase GABA to increase sleepiness
Which would be the first line appropriate pharmacological agent for PTSD? - Answer-Paroxetine
, What mediation is used to alleviate to help cognitive pain and physical symptoms in fibromyalgia? -
Answer-Milnacepran (Savella)
With the difficulty breathing is related hypothetically to the activation of what area of the brain? -
Answer-parabrachial nucleous
What medications are good for falling asleep "sleep induction" and are not addictive? - Answer-
Suvorexant (Belsmora)
Know the MOA of buspirone. Which receptor does it primarily act upon? - Answer-serotonin 1a 5HT1A
partial agonist
How does melatonin improve sleep? What receptors does it act on? Agonist or antatonist? - Answer-
Secreted by the pineal glad to attach to receptors in the suprachiasmic nucleus to regulate the circadian
rhythm; agonist
Current dx of generalized anxiety disorder (GAD), difficulty concentrating as well as problems falling
asleep. She gets very angry over basic things and is very moody in general, excessive stressful reactions,
concentrate, irritability. What is going on in her brain? - Answer-a. Dysfunction of amygdale and CTSC
(serotonin/nor-einephrine)
Pt is coming in for detox with a long hx of alcohol abuse, HTN, and cirrhosis. He reports 12 beers daily
for weeks. Has w/d seizures when he tries to stop drinking on his own. So he has elevated AST,
LFT....what agent would you choose to detox him? - Answer-lorazepam
Someone comes in with chronic hepatitis, also has chronic neuropathic pain. What medication would
you AVOID prescribing to this patient and why? - Answer-Cymbalta; elevates LFTs
Benzodiazepine patient education - Answer-Avoid ETOH may cause dizziness, may slow heart rate, avoid
sedating antihistamines
What is the medication that is the antidote for alprazolam? - Answer-flumazenil
What is the MOA of pregabalin that makes it alleviate pain for people with fibromyalgia or chronic
fatigue? - Answer-binds to the alpha 2 delta sub-units of voltage sensitive calcium channels
What is an antagonist of caffeine - Answer-adenosine
Diagnose this pt: Patient comes in with a CC of anxiety. She has been excessively worrying, increased
arousal, increased tiredness and irritability. What is the primary and least likely diagnosis? - Answer-
GAD; Panic Disorder
Somebody w/ anxiety worries about having a panic attack, in addition has mood changes to avoid things
in order to not have a panic attack. - Answer-Panic disorder
A woman was raped, and continues to have fear of opposite sex on her way to parking garage. Which
two areas of the brain are involved? - Answer-amygdala and hippocampus
MOA of modafinil (Provigil). How does it promote normal wakefulness - Answer-histamine, NE at alpha
adrenergic receptor sites, dopamine at D2 receptors
What is the MOA of eszopiclone? What receptors does it act on? - Answer-Binds to GABA receptors to
increase GABA to increase sleepiness
Which would be the first line appropriate pharmacological agent for PTSD? - Answer-Paroxetine
, What mediation is used to alleviate to help cognitive pain and physical symptoms in fibromyalgia? -
Answer-Milnacepran (Savella)
With the difficulty breathing is related hypothetically to the activation of what area of the brain? -
Answer-parabrachial nucleous
What medications are good for falling asleep "sleep induction" and are not addictive? - Answer-
Suvorexant (Belsmora)
Know the MOA of buspirone. Which receptor does it primarily act upon? - Answer-serotonin 1a 5HT1A
partial agonist
How does melatonin improve sleep? What receptors does it act on? Agonist or antatonist? - Answer-
Secreted by the pineal glad to attach to receptors in the suprachiasmic nucleus to regulate the circadian
rhythm; agonist
Current dx of generalized anxiety disorder (GAD), difficulty concentrating as well as problems falling
asleep. She gets very angry over basic things and is very moody in general, excessive stressful reactions,
concentrate, irritability. What is going on in her brain? - Answer-a. Dysfunction of amygdale and CTSC
(serotonin/nor-einephrine)
Pt is coming in for detox with a long hx of alcohol abuse, HTN, and cirrhosis. He reports 12 beers daily
for weeks. Has w/d seizures when he tries to stop drinking on his own. So he has elevated AST,
LFT....what agent would you choose to detox him? - Answer-lorazepam
Someone comes in with chronic hepatitis, also has chronic neuropathic pain. What medication would
you AVOID prescribing to this patient and why? - Answer-Cymbalta; elevates LFTs
Benzodiazepine patient education - Answer-Avoid ETOH may cause dizziness, may slow heart rate, avoid
sedating antihistamines
