COMLEX LEVEL 1 MICROBIOLOGY EXAM 2026-
2027 QUESTIONS AND ANSWERS GRADED A+
Main virulence factor for Staph aureus
Protein A
IVDU causes rapid onset bacterial endocarditis (what bacteria)
Staph aureus
-Tricuspid valve most commonly affected
-"Tricuspid valve endocarditis"
Most common cause of Toxic Shock Syndrome
Staph aureus
-Hx of nasal packing or tampon in for too long
Treatment for Staph aureus (MSSA)
Nafcillin
,-"Naf for Staph"
Pnemonic for Cornybacterium diptheria
"ABCDEFG"
-ADP-ribosylation, Beta-prophage, Corynebacterium, Diptheriae, Elongation
Factor 2, Granules
Virulence factor for Gram (-) rods
LPS
-Lipopolysaccharide
Pt with history of dental trauma or dental caries that develops cardiac problems
1) Strep viridans
2) Strep mutans
3) Strep sanguineous
Two times for Periodic Acid-Schiff (PAS)
1) Whipple's Disease
2) Alpha1-antitrypsin deficiency
,Peptidoglycan (cell wall) synthesis is is inhibited by:
-Beta lactams
Community Acquired MRSA
-Pt will have recurrent cellulitis or boils
-Contact sports, prisoners/inmates, military recruits
-Tx: Trimethoprim-sulfamethoxazole
Most important virulence factor for Strep pyogenes
M protein
-Prevents phagocytosis and complement activation
-Molecular mimicry
Rheumatic Fever
-Strep pyogenes
-JONES criteria
, AD
Thick, golden colored crust
Impetigo
-Strep pyogenes
-Tx: topical mupirocin
Erysipelas
-Due to Strep pyogenes
-Redness/swelling of an extremity w/ bull and enlarged lymph nodes
Scarlet Fever
-Strep pyogenes
-Pyrogenic exotoxin
-1) Strawberry tongue, 2) Sandpaper rash
Necrotizing fasciitis w/ Strep progenies infection
-Exotoxin B
-Pain out of proportion to PE findings
2027 QUESTIONS AND ANSWERS GRADED A+
Main virulence factor for Staph aureus
Protein A
IVDU causes rapid onset bacterial endocarditis (what bacteria)
Staph aureus
-Tricuspid valve most commonly affected
-"Tricuspid valve endocarditis"
Most common cause of Toxic Shock Syndrome
Staph aureus
-Hx of nasal packing or tampon in for too long
Treatment for Staph aureus (MSSA)
Nafcillin
,-"Naf for Staph"
Pnemonic for Cornybacterium diptheria
"ABCDEFG"
-ADP-ribosylation, Beta-prophage, Corynebacterium, Diptheriae, Elongation
Factor 2, Granules
Virulence factor for Gram (-) rods
LPS
-Lipopolysaccharide
Pt with history of dental trauma or dental caries that develops cardiac problems
1) Strep viridans
2) Strep mutans
3) Strep sanguineous
Two times for Periodic Acid-Schiff (PAS)
1) Whipple's Disease
2) Alpha1-antitrypsin deficiency
,Peptidoglycan (cell wall) synthesis is is inhibited by:
-Beta lactams
Community Acquired MRSA
-Pt will have recurrent cellulitis or boils
-Contact sports, prisoners/inmates, military recruits
-Tx: Trimethoprim-sulfamethoxazole
Most important virulence factor for Strep pyogenes
M protein
-Prevents phagocytosis and complement activation
-Molecular mimicry
Rheumatic Fever
-Strep pyogenes
-JONES criteria
, AD
Thick, golden colored crust
Impetigo
-Strep pyogenes
-Tx: topical mupirocin
Erysipelas
-Due to Strep pyogenes
-Redness/swelling of an extremity w/ bull and enlarged lymph nodes
Scarlet Fever
-Strep pyogenes
-Pyrogenic exotoxin
-1) Strawberry tongue, 2) Sandpaper rash
Necrotizing fasciitis w/ Strep progenies infection
-Exotoxin B
-Pain out of proportion to PE findings
