NURSING PHARMACOLOGY FINAL
EXAM QUESTIONS & VERIFIED
CORRECT ANSWERS RATED 100%
COMPLETE
Drug - CORRECT ANSWER any chemical that affects living processes
Pharmacology - CORRECT ANSWER the study of drugs and their effects on living
processes (plants, body tissues, etc.)
Clinical Pharmacology - CORRECT ANSWER the study of drugs in HUMANS
Pharmacotherapeutics - CORRECT ANSWER the use of drugs to diagnose, prevent,
and treat illnesses as well as to prevent pregnancy
Minimal Effective Concentration - CORRECT ANSWER the smallest dose of a drug
that produces the desired effect
Toxic Concentration - CORRECT ANSWER the dose of a drug that produces toxic
effects
Therapeutic Range - CORRECT ANSWER between the MEC & the TC; gets desired
effect(s) from drug without toxic side effects
P450 System - CORRECT ANSWER an enzyme that alters drug metabolism
-accelerates renal excretion
-inactivates drug
-enhances drug
-activates prodrugs
Prodrugs - CORRECT ANSWER drugs that are not activated (inert) until they pass
through the liver
First-pass Effect - CORRECT ANSWER deactivation of drug by liver after GI
absorption
Drug Half-Life - CORRECT ANSWER time it takes for drug levels to decrease by 50%
-it takes five half-lives to maintain a normal therapeutic range
, Loading Dose - CORRECT ANSWER drugs with short half-lives get a larger initial dose
in order to achieve therapeutic range
Maintenance Dose - CORRECT ANSWER small doses given to maintain therapeutic
range
ED50 (Average Effective Dose) - CORRECT ANSWER the dose that produces the
desired effects in 50% of the population
Therapeutic Index - CORRECT ANSWER = LD50 / ED50
-average lethal dose / average effective dose
-the higher the number, the safer the drug
Alpha1 Receptors - CORRECT ANSWER Sympathetic
-Adrenergic Receptor
-vasculature
-vasoconstriction
-pupil dilation
-ejaculation
-bladder neck contraction
Alpha2 Receptors - CORRECT ANSWER Sympathetic
-Adrenergic Receptor
-minimal
Beta1 Receptors - CORRECT ANSWER Sympathetic
-Adrenergic receptor
-heart & kidney
-increase HR, force of contraction & velocity of conduction
-Renin release
Beta2 Receptors - CORRECT ANSWER Sympathetic
-Adrenergic receptor
-bronchodilation
-relaxation of uterine muscle
-glycogenolysis
Nicotinic n - CORRECT ANSWER Paraympathetic
-cholinergic receptor
-promotes release of epinephrine
Nicotinic m - CORRECT ANSWER Parasympathetic
-cholinergic receptor
-contraction of skeletal muscle
M1 Receptor - CORRECT ANSWER Parasympathetic
EXAM QUESTIONS & VERIFIED
CORRECT ANSWERS RATED 100%
COMPLETE
Drug - CORRECT ANSWER any chemical that affects living processes
Pharmacology - CORRECT ANSWER the study of drugs and their effects on living
processes (plants, body tissues, etc.)
Clinical Pharmacology - CORRECT ANSWER the study of drugs in HUMANS
Pharmacotherapeutics - CORRECT ANSWER the use of drugs to diagnose, prevent,
and treat illnesses as well as to prevent pregnancy
Minimal Effective Concentration - CORRECT ANSWER the smallest dose of a drug
that produces the desired effect
Toxic Concentration - CORRECT ANSWER the dose of a drug that produces toxic
effects
Therapeutic Range - CORRECT ANSWER between the MEC & the TC; gets desired
effect(s) from drug without toxic side effects
P450 System - CORRECT ANSWER an enzyme that alters drug metabolism
-accelerates renal excretion
-inactivates drug
-enhances drug
-activates prodrugs
Prodrugs - CORRECT ANSWER drugs that are not activated (inert) until they pass
through the liver
First-pass Effect - CORRECT ANSWER deactivation of drug by liver after GI
absorption
Drug Half-Life - CORRECT ANSWER time it takes for drug levels to decrease by 50%
-it takes five half-lives to maintain a normal therapeutic range
, Loading Dose - CORRECT ANSWER drugs with short half-lives get a larger initial dose
in order to achieve therapeutic range
Maintenance Dose - CORRECT ANSWER small doses given to maintain therapeutic
range
ED50 (Average Effective Dose) - CORRECT ANSWER the dose that produces the
desired effects in 50% of the population
Therapeutic Index - CORRECT ANSWER = LD50 / ED50
-average lethal dose / average effective dose
-the higher the number, the safer the drug
Alpha1 Receptors - CORRECT ANSWER Sympathetic
-Adrenergic Receptor
-vasculature
-vasoconstriction
-pupil dilation
-ejaculation
-bladder neck contraction
Alpha2 Receptors - CORRECT ANSWER Sympathetic
-Adrenergic Receptor
-minimal
Beta1 Receptors - CORRECT ANSWER Sympathetic
-Adrenergic receptor
-heart & kidney
-increase HR, force of contraction & velocity of conduction
-Renin release
Beta2 Receptors - CORRECT ANSWER Sympathetic
-Adrenergic receptor
-bronchodilation
-relaxation of uterine muscle
-glycogenolysis
Nicotinic n - CORRECT ANSWER Paraympathetic
-cholinergic receptor
-promotes release of epinephrine
Nicotinic m - CORRECT ANSWER Parasympathetic
-cholinergic receptor
-contraction of skeletal muscle
M1 Receptor - CORRECT ANSWER Parasympathetic
