PATHO 3304 Exam 1 (NURS 3304 KSU) Questions With
Complete Solutions
Complement protein functions include ___________________
(coating of the pathogen to make appearance difficult and thus
recognizable by macrophages), _____________________
(activates mast cells, basophils, neutrophils, and macrophages),
__________________ (causes cell lysis), and the elimination of
_________________ (antibody complexes on RBCs are killed
in spleen)
Opsonization, inflammation, cytolysis, antigen
Pro-inflammatory chemicals include
histamine, prostaglandins, leukotrienes, and bradykinin
Both basophils and mast cells contain secretory granules that
store _______________ and heparin.
histamine
Cellular injury/pathogenic invasion response
,Arachidonic Acid Pathways
Arachidonic acid is produced when there is tissue injuries; it is
metabolized to produce inflammatory chemicals; most important
ones are prostaglandins and leukotrienes
Aspirin and NSAIDs block the part of arachidonic acid pathway
that produces prostaglandins and thromboxane (promotes
platelet function); because of this, taking an aspirin will
(thin/thicken) the blood.
thin
__________ inflammation is generally either resolved or can
lead to scarring/fibrosis
Acute
___________ inflammation is a result of recurring or
progressive inflammatory responses, which can lead to tissue
damage; examples include rheumatoid arthritis, Lupus, chronic
hepatitis
, Chronic
Adaptive immunity includes three major groups of cells:
_______________ immunity (T lymphocytes),
______________ immunity (B cells), and _________________
cells (antigen-presenting cells_
cellular, humoral, accessory
antigen presenting cells
dendritic cells, macrophages, B cells
Humoral vs Cell Mediated Immunity
Describe the B-cell to plasma pathway, and describe the three
functions that plasma cell antibodies aid in.
B-cells are activated by antigen and cytokines (released via
helper T cells), where they then differentiate to plasma cells.
Plasma cells then begin to secrete antibodies, which aid in
neutralization (antibody prevents bacterial adherence);
opsonization (antibody promotes phagocytosis); and
Complete Solutions
Complement protein functions include ___________________
(coating of the pathogen to make appearance difficult and thus
recognizable by macrophages), _____________________
(activates mast cells, basophils, neutrophils, and macrophages),
__________________ (causes cell lysis), and the elimination of
_________________ (antibody complexes on RBCs are killed
in spleen)
Opsonization, inflammation, cytolysis, antigen
Pro-inflammatory chemicals include
histamine, prostaglandins, leukotrienes, and bradykinin
Both basophils and mast cells contain secretory granules that
store _______________ and heparin.
histamine
Cellular injury/pathogenic invasion response
,Arachidonic Acid Pathways
Arachidonic acid is produced when there is tissue injuries; it is
metabolized to produce inflammatory chemicals; most important
ones are prostaglandins and leukotrienes
Aspirin and NSAIDs block the part of arachidonic acid pathway
that produces prostaglandins and thromboxane (promotes
platelet function); because of this, taking an aspirin will
(thin/thicken) the blood.
thin
__________ inflammation is generally either resolved or can
lead to scarring/fibrosis
Acute
___________ inflammation is a result of recurring or
progressive inflammatory responses, which can lead to tissue
damage; examples include rheumatoid arthritis, Lupus, chronic
hepatitis
, Chronic
Adaptive immunity includes three major groups of cells:
_______________ immunity (T lymphocytes),
______________ immunity (B cells), and _________________
cells (antigen-presenting cells_
cellular, humoral, accessory
antigen presenting cells
dendritic cells, macrophages, B cells
Humoral vs Cell Mediated Immunity
Describe the B-cell to plasma pathway, and describe the three
functions that plasma cell antibodies aid in.
B-cells are activated by antigen and cytokines (released via
helper T cells), where they then differentiate to plasma cells.
Plasma cells then begin to secrete antibodies, which aid in
neutralization (antibody prevents bacterial adherence);
opsonization (antibody promotes phagocytosis); and
