THIS DOCUMENT BELONGS TO TESTBANKSPROF
Test Bank for Modern Blood Banking & Transfusion Practices 7th
Edition
By Denise M Harmening
All Chapter (1-29) |Q&A Verified |Grade A+ Assured
ISBN 9780803668881
~1~
, THIS DOCUMENT BELONGS TO TESTBANKSPROF
TABLE OF CONTENTS
Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends.... 3
Chapter 2. Basic Genetics ................................................................................................... 11
Chapter 3. Fundamentals of Immunology .......................................................................... 18
Chapter 4. Concepts in Molecular Biology ......................................................................... 31
Chapter 5. The Antiglobulin Test ....................................................................................... 40
Chapter 6. The ABO Blood Group System ........................................................................... 49
Chapter 7. The Rh Blood Group System ............................................................................. 63
Chapter 8. Blood Group Terminology and the Other Blood Groups................................... 74
Chapter 9. Detection and Identification of Antibodies .................................................... 114
Chapter 10. Pre-Transfusion Testing ............................................................................... 131
Chapter 11. Overview of the Routine Blood Bank Laboratory ......................................... 144
Chapter 12. Other Technologies and Automation ............................................................ 152
Chapter 13. Donor Screening and Component Preparation ............................................ 156
Chapter 14. Apheresis ...................................................................................................... 163
Chapter 15. Transfusion Therapy .................................................................................... 175
Chapter 16. Adverse Effects of Blood Transfusion ........................................................... 196
Chapter 17. Cellular Therapy ........................................................................................... 215
Chapter 18. Transfusion-Transmitted Diseases .............................................................. 217
Chapter 19. Hemolytic Disease of the Fetus and Newborn .............................................. 225
Chapter 20. Autoimmune Hemolytic Anemias ................................................................. 236
Chapter 21. The HLA System ............................................................................................ 249
Chapter 22. Relationship Testing ..................................................................................... 259
Chapter 23. Quality Management .................................................................................... 264
Chapter 25. Transfusion Safety and Federal Regulatory Requirements .......................... 271
Chapter 26. Laboratory Information Systems.................................................................. 277
Chapter 27. Medicolegal and Ethical Aspects of Providing Blood Collection and
Transfusion Services ........................................................................................................ 284
Chapter 28. Tissue Banking: A New Role for the Transfusion Service ............................. 290
~2~
, THIS DOCUMENT BELONGS TO TESTBANKSPROF
Answers at the End of Each Chapter
Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current
Trends
Multiple Choice
Identify the choice that best completes the statement or answers the question.
1. Which metabolic pathway is responsible for generating 90% of the ATP for the
RBC?
a. Pentose phosphate shunt c. Glycolysis
b. Luebering-Rapoport shunt d. Methemoglobin reductase
2. A unit of blood was returned to the blood bank before it was spiked. Apparently
the patient’s IV failed. The unit of blood was outside the blood bank for 35 minutes.
Which of the statements below is most accurate?
a. The unit of blood should be discarded immediately.
b. The unit of blood can be returned to inventory.
c. The unit of blood must be transfused within 4 hours or be discarded at the end of
that time.
d. The unit of blood must be transfused with 24 hours.
3. What is the average diameter of a platelet?
a. 5 to 10 µm c. 1 to 2 µm
b. 2 to 4 µm d. 4 to 6 µm
4. In the normal hemoglobin-oxygen dissociation curve, what percentage of oxygen
is released to the tissues when PO2 averages 40 mm Hg?
a. 75% c. 100%
b. 25% d. 50%
5. What factors are known to influence platelet metabolism and function?
a. Storage temperature c. Platelet count
b. Initial pH d. All of the above
6. Which of the following red blood cell morphologies may be present on the
peripheral blood smear as a result of loss of RBC membrane?
a. Spherocytes c. Burr cells
b. Target cells d. Schistocytes
7. What does the term autologous transfusion refer to?
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a. A parent donating blood for his or her child
b. An individual donating blood for a friend
c. An individual donating blood for a relative
d. An individual donating blood for his or her own transfusion
8. What is the primary function of hemoglobin?
a. Iron metabolism c. Oxygen transport
b. Porphyrin synthesis d. Signal transduction
9. All of the following areas of red blood cell biology are crucial for normal
erythrocyte survival except:
a. Cellular metabolism. c. Site of the ABO antigen attachment.
b. RBC membrane. d. Hemoglobin structure.
10. What is the correct biochemical composition of the RBC membrane?
a. 52% protein, 40% lipid, 8% carbohydrate
b. 40% protein, 8% lipid, 52% carbohydrate
c. 8% protein, 52% lipid, 40% carbohydrate
d. 8% lipid, 40% carbohydrate, 52% protein
11. All of the following biochemical changes are associated with loss of red blood
cell viability upon storage
except:
a. Decreased pH. c. Increased ATP level.
b. Loss of red blood cell function. d. Decreased glucose consumption.
12. Which red blood cell preservative has a storage time of 35 days?
a. ACD c. AS-1
b. CPDA-1 d. CPD
~4~
Test Bank for Modern Blood Banking & Transfusion Practices 7th
Edition
By Denise M Harmening
All Chapter (1-29) |Q&A Verified |Grade A+ Assured
ISBN 9780803668881
~1~
, THIS DOCUMENT BELONGS TO TESTBANKSPROF
TABLE OF CONTENTS
Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends.... 3
Chapter 2. Basic Genetics ................................................................................................... 11
Chapter 3. Fundamentals of Immunology .......................................................................... 18
Chapter 4. Concepts in Molecular Biology ......................................................................... 31
Chapter 5. The Antiglobulin Test ....................................................................................... 40
Chapter 6. The ABO Blood Group System ........................................................................... 49
Chapter 7. The Rh Blood Group System ............................................................................. 63
Chapter 8. Blood Group Terminology and the Other Blood Groups................................... 74
Chapter 9. Detection and Identification of Antibodies .................................................... 114
Chapter 10. Pre-Transfusion Testing ............................................................................... 131
Chapter 11. Overview of the Routine Blood Bank Laboratory ......................................... 144
Chapter 12. Other Technologies and Automation ............................................................ 152
Chapter 13. Donor Screening and Component Preparation ............................................ 156
Chapter 14. Apheresis ...................................................................................................... 163
Chapter 15. Transfusion Therapy .................................................................................... 175
Chapter 16. Adverse Effects of Blood Transfusion ........................................................... 196
Chapter 17. Cellular Therapy ........................................................................................... 215
Chapter 18. Transfusion-Transmitted Diseases .............................................................. 217
Chapter 19. Hemolytic Disease of the Fetus and Newborn .............................................. 225
Chapter 20. Autoimmune Hemolytic Anemias ................................................................. 236
Chapter 21. The HLA System ............................................................................................ 249
Chapter 22. Relationship Testing ..................................................................................... 259
Chapter 23. Quality Management .................................................................................... 264
Chapter 25. Transfusion Safety and Federal Regulatory Requirements .......................... 271
Chapter 26. Laboratory Information Systems.................................................................. 277
Chapter 27. Medicolegal and Ethical Aspects of Providing Blood Collection and
Transfusion Services ........................................................................................................ 284
Chapter 28. Tissue Banking: A New Role for the Transfusion Service ............................. 290
~2~
, THIS DOCUMENT BELONGS TO TESTBANKSPROF
Answers at the End of Each Chapter
Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current
Trends
Multiple Choice
Identify the choice that best completes the statement or answers the question.
1. Which metabolic pathway is responsible for generating 90% of the ATP for the
RBC?
a. Pentose phosphate shunt c. Glycolysis
b. Luebering-Rapoport shunt d. Methemoglobin reductase
2. A unit of blood was returned to the blood bank before it was spiked. Apparently
the patient’s IV failed. The unit of blood was outside the blood bank for 35 minutes.
Which of the statements below is most accurate?
a. The unit of blood should be discarded immediately.
b. The unit of blood can be returned to inventory.
c. The unit of blood must be transfused within 4 hours or be discarded at the end of
that time.
d. The unit of blood must be transfused with 24 hours.
3. What is the average diameter of a platelet?
a. 5 to 10 µm c. 1 to 2 µm
b. 2 to 4 µm d. 4 to 6 µm
4. In the normal hemoglobin-oxygen dissociation curve, what percentage of oxygen
is released to the tissues when PO2 averages 40 mm Hg?
a. 75% c. 100%
b. 25% d. 50%
5. What factors are known to influence platelet metabolism and function?
a. Storage temperature c. Platelet count
b. Initial pH d. All of the above
6. Which of the following red blood cell morphologies may be present on the
peripheral blood smear as a result of loss of RBC membrane?
a. Spherocytes c. Burr cells
b. Target cells d. Schistocytes
7. What does the term autologous transfusion refer to?
~3~
, THIS DOCUMENT BELONGS TO TESTBANKSPROF
a. A parent donating blood for his or her child
b. An individual donating blood for a friend
c. An individual donating blood for a relative
d. An individual donating blood for his or her own transfusion
8. What is the primary function of hemoglobin?
a. Iron metabolism c. Oxygen transport
b. Porphyrin synthesis d. Signal transduction
9. All of the following areas of red blood cell biology are crucial for normal
erythrocyte survival except:
a. Cellular metabolism. c. Site of the ABO antigen attachment.
b. RBC membrane. d. Hemoglobin structure.
10. What is the correct biochemical composition of the RBC membrane?
a. 52% protein, 40% lipid, 8% carbohydrate
b. 40% protein, 8% lipid, 52% carbohydrate
c. 8% protein, 52% lipid, 40% carbohydrate
d. 8% lipid, 40% carbohydrate, 52% protein
11. All of the following biochemical changes are associated with loss of red blood
cell viability upon storage
except:
a. Decreased pH. c. Increased ATP level.
b. Loss of red blood cell function. d. Decreased glucose consumption.
12. Which red blood cell preservative has a storage time of 35 days?
a. ACD c. AS-1
b. CPDA-1 d. CPD
~4~
