ASU MEPN NUR 545 ADVANCED PHARM- EXAM 1 UPDATED
WITH MOST TESTED QUESTIONS AND ANSWERS | GRADED A+
| ASSURED SUCCESS WITH DETAILED RATIONALES
1. Which term best describes a drug that produces the expected therapeutic response?
A. Safety
B. Selectivity
C. Effectiveness
D. Therapeutic index
Correct Answer: C. Effectiveness
Rationale:
Effectiveness refers to the drug’s ability to elicit the desired or expected therapeutic response. A
drug may be safe but ineffective, which would negate its clinical usefulness.
2. Which statement best defines drug safety?
A. A drug that has no adverse effects
B. A drug that does not produce harmful effects when used appropriately
C. A drug with a wide therapeutic index
D. A drug that is selective for one receptor
Correct Answer: B
Rationale:
All drugs carry risk. Safety means the likelihood of harm is minimized through proper drug
selection, dosing, and monitoring—not that adverse effects are absent.
3. Selectivity refers to which pharmacologic property?
A. Ability to cross the blood–brain barrier
B. Ability to bind irreversibly
C. Ability to elicit only the intended response
D. Ability to avoid adverse effects
Correct Answer: C
,ESTUDYR
Rationale:
Selectivity describes how specifically a drug acts on its intended receptor. However, selectivity
does not guarantee safety.
4. The therapeutic objective of drug therapy is to:
A. Eliminate all adverse effects
B. Maximize drug potency
C. Provide maximum benefit with minimal harm
D. Achieve steady-state quickly
Correct Answer: C
Rationale:
The primary goal of pharmacotherapy is to balance benefit and risk, not eliminate risk entirely.
5. Which nursing responsibility best supports medication safety?
A. Administering medications quickly
B. Delegating medication administration
C. Anticipating adverse drug reactions
D. Limiting patient education
Correct Answer: C
Rationale:
Proactive assessment and anticipation of adverse reactions are central nursing responsibilities
and prevent patient harm.
6. Which action is most important during pre-administration assessment?
A. Reviewing drug cost
B. Identifying high-risk patients
C. Timing meals
D. Checking pharmacy stock
Correct Answer: B
Rationale:
Patients with renal disease, liver disease, advanced age, pregnancy, or polypharmacy are at
higher risk for adverse effects.
, ESTUDYR
7. Which patient is considered high-risk for drug therapy complications?
A. Healthy 25-year-old
B. Older adult with renal disease
C. Middle-aged athlete
D. Patient with seasonal allergies
Correct Answer: B
Rationale:
Renal impairment affects drug elimination, increasing toxicity risk.
8. Which information must be included in patient medication education?
A. Drug manufacturer
B. Insurance coverage
C. Expected therapeutic response
D. Pharmacy hours
Correct Answer: C
Rationale:
Patients must understand what therapeutic effects to expect so they can identify effectiveness or
failure.
9. Pharmacokinetics is best defined as:
A. What the drug does to the body
B. How the drug moves through the body
C. Drug receptor binding
D. Therapeutic index
Correct Answer: B
Rationale:
Pharmacokinetics includes absorption, distribution, metabolism, and excretion (ADME).