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Exam (elaborations)

PANCE Blueprint Obstetrics and Gynecology 2026: High-Yield PA Review

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PANCE Blueprint Obstetrics and Gynecology 2026 is a comprehensive, blueprint-aligned study resource designed to help physician assistant students master women’s health topics tested on the PANCE exam. This guide covers high-yield obstetric and gynecologic conditions including prenatal care, labor and delivery, postpartum complications, contraception, menstrual disorders, infertility, sexually transmitted infections, gynecologic cancers, and obstetric emergencies. Emphasizing clinical presentation, diagnostics, and management, this resource is structured according to the PANCE blueprint to support efficient review and exam readiness for the 2026 PANCE.

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PANCE Blueprint_
Obstetrics and Gynecology
Exam

2026
Questions and Answers
(A+ Grade Guarantee)

,When does RH Alloimmunization When an Rh negative mother carries an Rh positive fetus
occur?

Accelerations are normal and expected;
Which is more worrisome in fetal Late decelerations are worrisome and indicate prompt delivery
heart tones? ≥ 2 HR
Accelerations, or repetetive late
decelerations?

Given to Rh negative mothers at 28 weeks and within 72 hours
When do mothers require
Rhogam? after delivery

hemolytic anemia;
jaundice;
kernicterus;
What 5 symptoms does Rh hepatosplenomegaly;
alloimmunization cause? fetal hydrops (fluid accumulation)



hCG is less than 2000 and does not double in 48-72 hours
What medical treatment can be
used for an ecoptic pregnancy?

Gestational Trophoblastic Disease confirmed with ultrasound and
B-hCG

A patient presents in her 7th
week of pregnancy for her 1st
trimester checkup. Her uterus
that is larger than expected
showing a fundal height that you
would expect at 14 weeks. Her
main complaint is of some scant
brownish discharge and terrible
morning sickness resulting in
multiple episodes of emesis
every day. What am I suspecting
and what should I do to confirm
it?




Before 34 weeks: anti-strep antibiotics and steroids and tocolytics;
What management should I offer After 37 weeks Admit and induce with oxytocin (not technically a
for premature membrane premature rupture)
rupture?


Fetal fibronectin (20-34 weeks);
List 3 tests that can confirm Fern test;
premature membrane rupture pH >6.5
(PROM)


What is the most common cytomegalovirus
neonatal infection?

If it presents initially after 20 weeks and resolves about 12 weeks
post partum
At what point can a pregnant
patient's hypertension be
considered gestational and when
should it normally resolve?


2026

, (associated with pre-eclampsia)
Hemolysis;
What is HELLP syndrome? Elevated Liver enzymes;
Low Platelets


24-28 wks
When do we begin screening
mothers for gestational diabetes?


What is the initial diagnostic 50g oral glucose challenge test positive if >140 after 1 hour;
criteria for gestational diabetes?

100g oral glucose challenge test is confirmatory if:
fasting >95;
What is the gold standard 1 hour>180;
diagnostic criteria for gestational 2 hour>155;
diabetes? 3 hour>140



@ 38 weeks if uncontrolled macrosomia ;
Macrosomia is a big complication @ 40 weeks if controlled or no macrosomia.
of gestational diabetes. When is
induction of labor indicated due to
this?


What is the treatment of choice Long Acting Insulin
for gestational diabetes?

Magnesium sulfate is given to prevent convulsions
What is our first priority for a
patient with pre-eclampsia and
why?

Larger than 4cm;
What are 4 contraindications for Fetal heart tones;
treating an ectopic pregnancy B-hCG greater than 5000;
with methotrexate? Ruptured ectopic


When BP is over 160/110 and proteinuria >5 in 24 hours (+1 on
When is pre-eclampsia dipstick);
considered severe and what do Promp delivery is indicated with MgSO4 and BP meds
we do?

Hydralazine (and/or Labetolol)
What BP medication is indicated
in Eclampsia or severe
preeclampsia?

Moderate chronic hypertension (gestational occurs later) treated
A woman presents in her 14th firstline with methyldopa
week of pregnancy for her regular
2nd trimester check up. Her BP is
reading 150/100. What is the
diagnosis and what treatment is
firstline?




2026

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Written in
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