TEST 2026 COMPLETE QUESTIONS AND
ANSWERS GRADED A+
⩥ how does acute alcohol use affect medications? Answer: increases
liver enzymes, which increases rate of metabolism
⩥ how does chronic use of alcohol effect medications? Answer: causes
liver damage which impairs metabolism
⩥ How does naltrexone work? Answer: By blocking opioid receptors
this blocks the reward of drinking
dont use in liver patients
⩥ How does acamprosate work? Answer: works on GABA and
glutamate pathway and is very effective in maintaining abstinence in
dependent drinkers even in severe cases
dont use in renal patients
, ⩥ How does Disulfiram (Antabuse) work? Answer: if someone drinks,
causes build up of acetyldehyde in system which causes very unpleasant
effects of alcohol
⩥ what is an important consideration when prescribing naltrexone?
Answer: patient must be completely free of opioids
can be given IM
⩥ what effect do hallucinogenics have on 5ht2a receptors? Answer:
agonism
⩥ How does nicotine work? Answer: It Directly Stimulate Dopaminergic
Neurons heading to the Nucleus Accumbens.
long term stimulation of receptors leads to desensitization- where no
longer react to nicotine
as receptors resensitize, they initiate craving and withdrawal
receptors will upregulate to compensate, which can increase cravings
further
⩥ What SSRI should be avoided in pregnancy? Answer: Paxil