TA TABLE OF CONTENT
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Chapter 1: Pharmacokinetics
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Chapter 2: Drug– S S
Receptor Interactions and Pharmacodynamics Chapter 3: The Autonomic Nervous System
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Chapter 4: Cholinergic Agonists Chapter 5: Cholinergic Antagonists Cha
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pter 6: Adrenergic Agonists Chapter 7: Adrenergic Antagonists
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Chapter 8: Drugs for Neurodegenerative Diseases Chapter 9: Anxiolytic and Hypnotic Drug
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s
Chapter 10: Antidepressants Chapter 11: Antipsychotic Drugs Chapter 1
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2: Drugs for Epilepsy Chapter 13: Anesthetics
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Chapter 14: Opioids
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Chapter 15: Drugs of Abuse Chapter 16: CNS Stimulants Chapter 17: An
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tihypertensives Chapter 18: Diuretics S S S
Chapter 19: Heart Failure
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Chapter 20: Antiarrhythmics Chapter 21: Antianginal Drugs
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Chapter 22: Anticoagulants and Antiplatelet Agents Chapter 23: Drugs for Hyperlipidemia
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Chapter 24: Pituitary and Thyroid Chapter 25: Drugs for Diabetes
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Chapter 26: Estrogens and Androgens Chapter 27: Adrenal Hormones
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Chapter 28: Drugs for Obesity
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Chapter 29: Drugs for Disorders of the Respiratory System Chapter 30: Antihistamines
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Chapter 31: Gastrointestinal and Antiemetic Drugs Chapter 32: Drugs for Urologic Disorde
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rs
Chapter 33: Drugs for Anemia
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Chapter 34: Drugs for Dermatologic Disorders Chapter 35: Drugs for Bone Disorders
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Chapter 36: Anti-S S
inflammatory, Antipyretic, and Analgesic Agents Chapter 37: Principles of Antimicrobial Therapy
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Chapter 38: Cell Wall Inhibitors
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Chapter 39: Protein Synthesis Inhibitors
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Chapter 40: Quinolones, Folic Acid Antagonists, and Urinary Tract Antiseptics Chapter 41: Antimycobacterial Drugs
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Chapter 42: Antifungal Drugs Chapter 43: Antiprotozoal Drugs Chapter
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44: Anthelmintic Drugs Chapter 45: Antiviral Drugs
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Chapter 46: Anticancer Drugs
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Chapter 47: Immunosuppressants Chapter 48: Clinical Toxicology
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,3. The nurse is teaching a patient who will be discharged home with a prescription for an enteric-
coated tablet. Which statement by the patient indicates understanding of the teaching?
a. I may crush the tablet and put it in applesauce to improve absorption.
b. I should consume acidic foods to enhance absorption of this medication.
c. I should expect a delay in onset of the drugs effects after taking the tablet.
d. I should take this medication with high-fat foods to improve its action.
ANS: C
Enteric-coated tablets resist disintegration in the acidic environment of the stomach and
disintegrate when they reach the small intestine. There is usually some delay in onset of actions
after taking these medications. Enteric-coated tablets should not be crushed or chewed, which
would alter the time and location of absorption. Acidic foods will not enhance the absorption of
the medication. The patient should not to eat high-fat food before ingesting an enteric-coated
tablet, because high-fat foods decrease the absorption rate.
DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 3
TOP: NURSING PROCESS: Nursing Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
4. A patient who is newly diagnosed with type 1 diabetes mellitus asks why insulin must be
given by subcutaneous injection instead of by mouth. The nurse will explain that this is because
a. absorption is diminished by the first-pass effects in the liver.
b. absorption is faster when insulin is given subcutaneously.
c. digestive enzymes in the gastrointestinal tract prevent absorption.
d. the oral form is less predictable with more adverse effects.
ANS: C
Insulin, growth hormones, and other protein-based drugs are destroyed in the small intestine by
digestive enzymes and must be given parenterally. Because insulin is destroyed by digestive
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, enzymes, it would not make it to the liver for metabolism with a first-pass effect. Subcutaneous
tissue has fewer blood vessels, so absorption is slower in such tissue. Insulin is given
subcutaneously because it is desirable to have it absorb slowly.
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3
TOP: NURSING PROCESS: Nursing Intervention: Patient Teaching
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
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