Pathology Questions and
Answers
Calcification, metastatic
Ans- Calcium infiltration into normal tissue. E.g. hypervitaminosis D.,
hyperparathyroidism
Calcification, dystrophic
Ans- Calcium infiltration into abnormal/damaged tissue E.g. atherosclerosis or
atheroma. Damage to tunica intima
Caseous (cheese like)
Ans- Combination of ischemic cell death & cell lysis. Tuberculosis, giant
epithelial cell
,Cloudy swelling
Ans- Albuminous. Membrane injured which effects ionic transfer.
AKA hydropic change
*cloudy swelling is reversible
Coagulation
Ans- Infarction (MI), blood vessels
*zymogen
Enzymatic
Ans- pancreas
Fatty
Ans- Liver, aka "nutmeg liver"
heart, aka "tabby cat heart"
,fatty dot > fatty streak > atheroma (fatty plaque) > fibroatheroma (fibrous
tissue, calcium)
Liquefaction
Ans- CNS E.g. brain melts, tertiary syphilis, leprosy
Skin (if from infection) tabes dorsalis
Wallerian
Ans- Peripheral nerves. Degenerates to the next node of ranvier. "dying back
phenomenon"
Zenker's (waxy)
Ans- Hyaline. Most common in skeletal muscle. Muscle replaced with hyaline
Degeneration of nucleus...
Ans- cell must die
Karyo = nucleus
, Karyolysis
Ans- nuclear fading/rupture (DNA breakdown: irreversible)
Karyorrhexis
Ans- Nuclear swelling (chromattin fragmentation)
Pyknosis
Ans- Nuclear condensation
AKA karyopyknosis
Developmental changes...
Ans-
Agenesis
Ans- absence of an organ (usually pair organ)