GENERAL PATHOLOGY FINAL EXAM 2026-
2027 QUESTIONS AND CORRECT ANSWERS
GRADED A+ LATEST
Most inflammatory activity takes places at the post capillary venule because of the
following characteristics except:
No surrounding basal lamina pericytes
All are major components of acute inflammation except
Fibroblast migration and deposition of collagen tumor
A critical function of inflammation is the delivery of WBC to the injury site. This
process is called transmigration.
FALSE
A 17 year old male suffers from acute viral hepatitis. Blood tests reveal elevated
liver enzymes (AST and ALT). The most likely cause of these elevated enzyme
levels is related to which of the following changes in his hepatocytes?
Cell lysis
Reversible cell injury feature includes the following except?
,Myelin figures
A 68 year old woman suffers the rapid onset of right hemiparesis (weakness on one
side of the body) and severe aphasia (inability to speak). Two months later a CT
scan of her head reveals a large cystic area in the left parietal lobe of her brain.
Which of the following pathologic processes accounts for this CT finding?
Liquifactive necrosis
Metabolic changes in aging include all of the following except
Decreased nutrient uptake
A 45 year old male suffers from acute myocardial ischemia. A biopsy of the
ischemic tissue would likely show?
Some condensation of nuclear contents
Which type of necrosis is associated with a predominance of heterolysis?
Coagulative
A process of apoptosis executioner caspases do all of the following except
Cleave DNA into random fragments
In the remodeling phase what type of collagen is replaced?
,Type 3
Which phase of wound healing is associated with the intermolecular cross-linking
of collagen?
Remodeling phase
Vascular maturation is associated with?
Increased levels of angiopoietins
All are acute phase proteins except
Plasminogen
Angiogenesis is a process that involves several signaling pathways. They include
the following except:
Kinin signaling
The remodeling phase of wound healing by primary intention includes all of the
following except:
Complete by 3 months in healthy individuals
, When macrophages enter particular organs they acquire new names:
TRUE
In an experiment, a tissue preparation is subjected to oxidant stress. There are
increased numbers of free radicals generated within the cells. Generation of which
of the following enzymes within these cells would most likely be protective?
Glutathione peroxidase
A 53 year old man suffers a cardiac arrest and his wife calls emergency services.
The paramedics arrive a few minutes later and begin life support measures. A
regular heart rate is established after 40 minutes of resuscitative efforts as he is
being transported to the hospital. A thrombolytic agent (tPA) is administered.
Which of the following cellular processes is most likely to occur in his
myocardium immediately following administration of the tPA?
Free radical injury
All are nuclear changes in irreversible cell injury except?
Autolysis
Hyperplasia is an increase in the size of the cells and eventually an increase in the
size of the organ.
False
2027 QUESTIONS AND CORRECT ANSWERS
GRADED A+ LATEST
Most inflammatory activity takes places at the post capillary venule because of the
following characteristics except:
No surrounding basal lamina pericytes
All are major components of acute inflammation except
Fibroblast migration and deposition of collagen tumor
A critical function of inflammation is the delivery of WBC to the injury site. This
process is called transmigration.
FALSE
A 17 year old male suffers from acute viral hepatitis. Blood tests reveal elevated
liver enzymes (AST and ALT). The most likely cause of these elevated enzyme
levels is related to which of the following changes in his hepatocytes?
Cell lysis
Reversible cell injury feature includes the following except?
,Myelin figures
A 68 year old woman suffers the rapid onset of right hemiparesis (weakness on one
side of the body) and severe aphasia (inability to speak). Two months later a CT
scan of her head reveals a large cystic area in the left parietal lobe of her brain.
Which of the following pathologic processes accounts for this CT finding?
Liquifactive necrosis
Metabolic changes in aging include all of the following except
Decreased nutrient uptake
A 45 year old male suffers from acute myocardial ischemia. A biopsy of the
ischemic tissue would likely show?
Some condensation of nuclear contents
Which type of necrosis is associated with a predominance of heterolysis?
Coagulative
A process of apoptosis executioner caspases do all of the following except
Cleave DNA into random fragments
In the remodeling phase what type of collagen is replaced?
,Type 3
Which phase of wound healing is associated with the intermolecular cross-linking
of collagen?
Remodeling phase
Vascular maturation is associated with?
Increased levels of angiopoietins
All are acute phase proteins except
Plasminogen
Angiogenesis is a process that involves several signaling pathways. They include
the following except:
Kinin signaling
The remodeling phase of wound healing by primary intention includes all of the
following except:
Complete by 3 months in healthy individuals
, When macrophages enter particular organs they acquire new names:
TRUE
In an experiment, a tissue preparation is subjected to oxidant stress. There are
increased numbers of free radicals generated within the cells. Generation of which
of the following enzymes within these cells would most likely be protective?
Glutathione peroxidase
A 53 year old man suffers a cardiac arrest and his wife calls emergency services.
The paramedics arrive a few minutes later and begin life support measures. A
regular heart rate is established after 40 minutes of resuscitative efforts as he is
being transported to the hospital. A thrombolytic agent (tPA) is administered.
Which of the following cellular processes is most likely to occur in his
myocardium immediately following administration of the tPA?
Free radical injury
All are nuclear changes in irreversible cell injury except?
Autolysis
Hyperplasia is an increase in the size of the cells and eventually an increase in the
size of the organ.
False
