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Terms in this set (41)
antimicrobials any compounds that kill or inhibit microorganisms
antibiotics antimicrobials, usually of low molecular weight,
naturally produced by microorganisms to inhibit or
kill other microorganisms
ex. penicillin and streptomycin
semi-synthetics antimicrobials that are chemically synthesized in
the laboratory and are not produced by microbial
biosynthesis at all
ex. sulfa drugs
healthcare acquired infections (HAIs) formerly nosocomial infections; acquired in
hospitals; MRSA is responsible for many hospital
infections
, Kirby-Bauer method used to determine the sensitivity or resistance of a
bacterium to an antimicrobial
performed by streaking a standardized inoculum of
the test organism on Mueller-Hinton medium, and
then paper disks containing specific concentrations
of an antimicrobial are deposited on the agar
surface. The antimicrobial diffuses out from the disk
into the agar, forming a concentration gradient. If
the agent inhibits or kills the test organism, there
will be a zone around the disk where no growth
occurs, called the zone of inhibition.
Mueller-Hinton II agar is the recommended
medium with pH between 7.2 and 7.4
zone of inhibition the zone around the disk where no growth occurs
if an agents inhibits the microorganism; affected by
diffusibility of the agent, size of the inoculum, the
type of medium, and other factors
antiseptics substances such as alcohol or betadine that inhibit
microbial growth or kill microorganisms but they
are gentle enough to be applied to living tissue; do
not destroy endospores
disinfectants chemical agents that are applied to inanimate
objects such as floors, walls, and tabletops to kill
microorganisms; damaging to living tissue
sterilants; sporocides destroy all microbial life, including endospores
ex. ethylene oxide