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ASCP MLS Hematology Exam COMPLETE 300
QUESTIONS AND CORRECT VERIFIED ANSWERS
LATEST UPDATE JUST RELEASED THIS YEAR
Question: What term describes the change in shape of erythrocytes seen on a Wright's-stained
peripheral blood smear?
A. Poikilocytosis
B. Anisocytosis
C. Hypochromia
D. Polychromasia - CORRECT ANSWER✔✔A. Variation in shape of the erythrocytes on a
peripheral
blood smear is poikilocytosis. Anisocytosis refers to a
change in size. Hypochromia is an increase in central
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pallor in erythrocytes. Polychromasia describes the bluish tinge of the immature erythrocytes
(reticulocytes) circulating in the peripheral blood.
Question: Calculate the mean cell hemoglobin concentration (MCHC) using the following
values:
Hgb: 15 g/dL (150 g/L)
Hct: 47 mL/dL (0.47)
RBC: 4.50 × 106/μL (4.50 × 1012/L)
A. 9.5% (.095)
B. 10.4% (.104)
C. 31.9% (.319)
D. 33.3% (.333) - CORRECT ANSWER✔✔C. MCHC is the average concentration of Hgb in red
cells expressed as a percentage. It expresses the ratio of the weight of Hgb to the volume of
erythrocytes and is calculated by dividing Hgb by the Hct, and then multiplying by 100. A
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decreased MCHC indicates that cells are hypochromic. In this example, (15 ÷ 47) × 100 = 31.9%.
The reference range for MCHC is 32%-36%.
Question: A manual white blood cell (WBC) count was performed. A total of 36 cells were
counted in all 9-mm^2 squares of a Neubauer-ruled hemacytometer. A 1:10 dilution was used.
What is the WBC count?
A. 0.4 × 10^9/L
B. 2.5 × 10^9/L
C. 4.0 × 10^9/L
D. 8.0 × 10^9/L - CORRECT ANSWER✔✔A. The formula used for calculating manual cell counts
using a hemacytometer is:
Number of cells counted × dilution factor × depth factor (10) divided by the area.
In this example, 36 × 10 × 10 = 3600 ÷ 9 = 400/mm^3 or 0.4 × 10^9/L.
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Question: When an erythrocyte containing iron granules is stained with Prussian blue, the cell
is called a:
A. Spherocyte
B. Leptocyte
C. Schistocyte
D. Siderocyte - CORRECT ANSWER✔✔D. Siderocytes are red cells containing iron granules
and are visible when stained with Prussian blue.
Question: A 7.0-mL ethylenediaminetetraacetic acid (EDTA) tube is received in the laboratory
containing only 2.0 mL of blood. If the laboratory is using manual techniques, which of the
following tests will most likely be erroneous?
A. RBC count
B. Hemoglobin (Hgb)
C. Hct
D. WBC count - CORRECT ANSWER✔✔C. Excessive anticoagulant causes shrinkage of cells;
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ASCP MLS Hematology Exam COMPLETE 300
QUESTIONS AND CORRECT VERIFIED ANSWERS
LATEST UPDATE JUST RELEASED THIS YEAR
Question: What term describes the change in shape of erythrocytes seen on a Wright's-stained
peripheral blood smear?
A. Poikilocytosis
B. Anisocytosis
C. Hypochromia
D. Polychromasia - CORRECT ANSWER✔✔A. Variation in shape of the erythrocytes on a
peripheral
blood smear is poikilocytosis. Anisocytosis refers to a
change in size. Hypochromia is an increase in central
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,Page 2 of 115
pallor in erythrocytes. Polychromasia describes the bluish tinge of the immature erythrocytes
(reticulocytes) circulating in the peripheral blood.
Question: Calculate the mean cell hemoglobin concentration (MCHC) using the following
values:
Hgb: 15 g/dL (150 g/L)
Hct: 47 mL/dL (0.47)
RBC: 4.50 × 106/μL (4.50 × 1012/L)
A. 9.5% (.095)
B. 10.4% (.104)
C. 31.9% (.319)
D. 33.3% (.333) - CORRECT ANSWER✔✔C. MCHC is the average concentration of Hgb in red
cells expressed as a percentage. It expresses the ratio of the weight of Hgb to the volume of
erythrocytes and is calculated by dividing Hgb by the Hct, and then multiplying by 100. A
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decreased MCHC indicates that cells are hypochromic. In this example, (15 ÷ 47) × 100 = 31.9%.
The reference range for MCHC is 32%-36%.
Question: A manual white blood cell (WBC) count was performed. A total of 36 cells were
counted in all 9-mm^2 squares of a Neubauer-ruled hemacytometer. A 1:10 dilution was used.
What is the WBC count?
A. 0.4 × 10^9/L
B. 2.5 × 10^9/L
C. 4.0 × 10^9/L
D. 8.0 × 10^9/L - CORRECT ANSWER✔✔A. The formula used for calculating manual cell counts
using a hemacytometer is:
Number of cells counted × dilution factor × depth factor (10) divided by the area.
In this example, 36 × 10 × 10 = 3600 ÷ 9 = 400/mm^3 or 0.4 × 10^9/L.
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Question: When an erythrocyte containing iron granules is stained with Prussian blue, the cell
is called a:
A. Spherocyte
B. Leptocyte
C. Schistocyte
D. Siderocyte - CORRECT ANSWER✔✔D. Siderocytes are red cells containing iron granules
and are visible when stained with Prussian blue.
Question: A 7.0-mL ethylenediaminetetraacetic acid (EDTA) tube is received in the laboratory
containing only 2.0 mL of blood. If the laboratory is using manual techniques, which of the
following tests will most likely be erroneous?
A. RBC count
B. Hemoglobin (Hgb)
C. Hct
D. WBC count - CORRECT ANSWER✔✔C. Excessive anticoagulant causes shrinkage of cells;
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