CMN 548 UNIT 5 EXAM(ACTUAL EXAM) WITH CORRECT ACTUAL QUESTIONS AND
CORRECTLY WELL DEFINED ANSWERS LATEST ALREADY GRADED A+ 2026
Potency - (ANSWER)refers to the relative dose required to achieve certain effects, not to the efficacy of
a drug
Agonist (full agonist) - (ANSWER)A drug that binds to a specific receptor producing an effect identical to
that usually produced by the neurotransmitter affecting that receptor
Pharmacodynamics - (ANSWER)The time course and intensity of a drug's effect/what the drug does to
the body
Pharmacokinetics - (ANSWER)What the body does to a drug
Tolerance - (ANSWER)Develops over time a need to use increased doses of a medication/drug to
maintain a clinical effect. Or, a decreased sensitivity to adverse effects of a drug
Stevens-Johnson Syndrome - (ANSWER)A systemic, immune-mediated reaction that can be fatal or
result in permanent scarring or blindness
Antagonist - (ANSWER)A compound that blinds to a receptor that blocks or reduces the action of
another substance at the receptor site
Hyponatremia - (ANSWER)Common symptoms of this medication side effect include confusion,
agitation, and lethargy. (tx with oxcarbazepine & SSRIs)
Therapeutic index - (ANSWER)ratio of the median toxic dose to the median effective dose
Somnolence - (ANSWER)Daytime sleepiness
Black Box Warning - (ANSWER)This warning reflects that a medication may cause a serious or even life-
threatening side effect
,CMN 548 UNIT 5 EXAM(ACTUAL EXAM) WITH CORRECT ACTUAL QUESTIONS AND
CORRECTLY WELL DEFINED ANSWERS LATEST ALREADY GRADED A+ 2026
Partial or Mixed Agonist - (ANSWER)A compound that elicits a partial pharmacological response at the
receptor site involved
Remission - (ANSWER)The degree of improvement to below the syndromal threshold of a disorder
Paradoxical - (ANSWER)A response to a drug that represents the clinical effect opposite of what is
expected
Inverse agonist - (ANSWER)An agent that binds to the same receptor site as an agonist but produces the
opposite pharmacological effect
4 major transmitters - (ANSWER)Dopamine, Serotonin, GABA, Norepinephrine
Dopamine transmitter affects? - (ANSWER)affects mood, Psychosis, ADHD, Addiction
Serotonin transmitter affects? - (ANSWER)Depression, aggression, OCD, Panic, GAD, Social Anxiety,
PTSD, Violence, Sexual dysfunction, substance addiction
Norepinephrine affects? - (ANSWER)Affects mood, anxiety, psychosis, ADHD (part), drug withdrawal
GABA affects? - (ANSWER)Fear, anxiety, worry
Irreversible MAOIs Types - (ANSWER)MAOa and MAOb
Irreversible MAOIs medications - (ANSWER)Phenelzine (Nardil)
isocarboxazid (Marplan)
tranylcypromine (Parnate)
, CMN 548 UNIT 5 EXAM(ACTUAL EXAM) WITH CORRECT ACTUAL QUESTIONS AND
CORRECTLY WELL DEFINED ANSWERS LATEST ALREADY GRADED A+ 2026
A single dose of MAOIs may persist in its inhibition of MAO for how long? - (ANSWER)because they
irreversibly inactivate MAOs, the therapeutic effect of a single dose of irreversible MAOIs may persist for
as long as 2 weeks
What are the most frequent adverse effects of MAOIs? - (ANSWER)orthostatic hypotension, insomnia,
weight gain, edema, sexual dysfunction
Reversible MAOIs (RIMAs) medications? - (ANSWER)Moclobemide (Maerix)
How long will it take to recover MAO activity after a final dose of RIMA? - (ANSWER)MAO activity
recovers completely 24-48 hrs after the last dose of a RIMA
MAOIs are used to treat what conditions? - (ANSWER)depression
panic disorder
social phobia
bulimia nervosa
ptsd
anginal pain
atypical facial pain
migraine
adhd
idiopathic orthostatic hypotension
Depression associated with TBI
Treatment for MAOI induced orthostatic hypotension? - (ANSWER)Avoid caffeine
intake of 2L of fluid/day
addition of dietary salt
adjust HTN meds
CORRECTLY WELL DEFINED ANSWERS LATEST ALREADY GRADED A+ 2026
Potency - (ANSWER)refers to the relative dose required to achieve certain effects, not to the efficacy of
a drug
Agonist (full agonist) - (ANSWER)A drug that binds to a specific receptor producing an effect identical to
that usually produced by the neurotransmitter affecting that receptor
Pharmacodynamics - (ANSWER)The time course and intensity of a drug's effect/what the drug does to
the body
Pharmacokinetics - (ANSWER)What the body does to a drug
Tolerance - (ANSWER)Develops over time a need to use increased doses of a medication/drug to
maintain a clinical effect. Or, a decreased sensitivity to adverse effects of a drug
Stevens-Johnson Syndrome - (ANSWER)A systemic, immune-mediated reaction that can be fatal or
result in permanent scarring or blindness
Antagonist - (ANSWER)A compound that blinds to a receptor that blocks or reduces the action of
another substance at the receptor site
Hyponatremia - (ANSWER)Common symptoms of this medication side effect include confusion,
agitation, and lethargy. (tx with oxcarbazepine & SSRIs)
Therapeutic index - (ANSWER)ratio of the median toxic dose to the median effective dose
Somnolence - (ANSWER)Daytime sleepiness
Black Box Warning - (ANSWER)This warning reflects that a medication may cause a serious or even life-
threatening side effect
,CMN 548 UNIT 5 EXAM(ACTUAL EXAM) WITH CORRECT ACTUAL QUESTIONS AND
CORRECTLY WELL DEFINED ANSWERS LATEST ALREADY GRADED A+ 2026
Partial or Mixed Agonist - (ANSWER)A compound that elicits a partial pharmacological response at the
receptor site involved
Remission - (ANSWER)The degree of improvement to below the syndromal threshold of a disorder
Paradoxical - (ANSWER)A response to a drug that represents the clinical effect opposite of what is
expected
Inverse agonist - (ANSWER)An agent that binds to the same receptor site as an agonist but produces the
opposite pharmacological effect
4 major transmitters - (ANSWER)Dopamine, Serotonin, GABA, Norepinephrine
Dopamine transmitter affects? - (ANSWER)affects mood, Psychosis, ADHD, Addiction
Serotonin transmitter affects? - (ANSWER)Depression, aggression, OCD, Panic, GAD, Social Anxiety,
PTSD, Violence, Sexual dysfunction, substance addiction
Norepinephrine affects? - (ANSWER)Affects mood, anxiety, psychosis, ADHD (part), drug withdrawal
GABA affects? - (ANSWER)Fear, anxiety, worry
Irreversible MAOIs Types - (ANSWER)MAOa and MAOb
Irreversible MAOIs medications - (ANSWER)Phenelzine (Nardil)
isocarboxazid (Marplan)
tranylcypromine (Parnate)
, CMN 548 UNIT 5 EXAM(ACTUAL EXAM) WITH CORRECT ACTUAL QUESTIONS AND
CORRECTLY WELL DEFINED ANSWERS LATEST ALREADY GRADED A+ 2026
A single dose of MAOIs may persist in its inhibition of MAO for how long? - (ANSWER)because they
irreversibly inactivate MAOs, the therapeutic effect of a single dose of irreversible MAOIs may persist for
as long as 2 weeks
What are the most frequent adverse effects of MAOIs? - (ANSWER)orthostatic hypotension, insomnia,
weight gain, edema, sexual dysfunction
Reversible MAOIs (RIMAs) medications? - (ANSWER)Moclobemide (Maerix)
How long will it take to recover MAO activity after a final dose of RIMA? - (ANSWER)MAO activity
recovers completely 24-48 hrs after the last dose of a RIMA
MAOIs are used to treat what conditions? - (ANSWER)depression
panic disorder
social phobia
bulimia nervosa
ptsd
anginal pain
atypical facial pain
migraine
adhd
idiopathic orthostatic hypotension
Depression associated with TBI
Treatment for MAOI induced orthostatic hypotension? - (ANSWER)Avoid caffeine
intake of 2L of fluid/day
addition of dietary salt
adjust HTN meds
