ESTUDYR
NURS 3010 - GI PT.1 - GERD & PUD- PHARMACOLOGY MOST
TESTED QUESTIONS AND ANSWERS GRADED A+ WITH
RATIONALES
1. What is the primary pharmacologic goal in the management of GERD?
A. Eliminate gastric bacteria
B. Increase intestinal motility only
C. Inhibit gastric acid secretion and protect the gastric mucosa
D. Stimulate bile secretion
Correct Answer: C
Rationale: GERD therapy focuses on decreasing acid exposure, improving gastric
emptying, and protecting the stomach lining.
2. Which medication classes inhibit gastric acid secretion?
A. Antacids and antibiotics
B. Prokinetics and mucosal protectants
C. Histamine-2 receptor antagonists and proton pump inhibitors (PPIs)
D. NSAIDs and corticosteroids
Correct Answer: C
Rationale: H2 blockers and PPIs directly suppress gastric acid production.
3. Which medications increase gastric emptying?
A. Antacids
B. PPIs
C. Prokinetic medications
D. Antibiotics
Correct Answer: C
Rationale: Prokinetics enhance GI motility and speed gastric emptying.
,ESTUDYR
4. Which medications protect the lining of the stomach?
A. PPIs only
B. Antibiotics
C. Antacids and mucosal protectants
D. Prokinetics
Correct Answer: C
Rationale: These agents neutralize acid or physically coat the gastric mucosa.
5. Which therapies are commonly used in peptic ulcer disease (PUD)?
A. Antiemetics only
B. Prokinetics only
C. PPIs, antiulcer agents, antacids, and antibiotics
D. Corticosteroids
Correct Answer: C
Rationale: PUD requires acid suppression, mucosal protection, and eradication of
H. pylori when present.
6. Which antibiotics are commonly used to treat H. pylori infection?
A. Vancomycin and ceftriaxone
B. Clarithromycin, amoxicillin, tetracycline
C. Ciprofloxacin and metronidazole only
D. Penicillin G only
Correct Answer: B
Rationale: These antibiotics are part of standard combination therapy for H.
pylori.
7. Which medications are classified as histamine-2 receptor antagonists?
A. Omeprazole and pantoprazole
B. Cimetidine and famotidine
, ESTUDYR
C. Sucralfate and misoprostol
D. Metoclopramide and ondansetron
Correct Answer: B
Rationale: Cimetidine and famotidine block H2 receptors in the stomach.
8. What is the mechanism of action of histamine-2 receptor antagonists?
A. Neutralize gastric acid
B. Destroy gastric bacteria
C. Block H2 receptors, reducing acid secretion
D. Increase prostaglandin production
Correct Answer: C
Rationale: Blocking H2 receptors decreases hydrogen ion concentration in the
stomach.
9. The therapeutic effect of H2 receptor antagonists is best described as:
A. Increased gastric motility
B. Suppressed gastric acid secretion
C. Increased bile release
D. Enhanced mucus production only
Correct Answer: B
Rationale: These medications reduce acid output and gastric acidity.
10. Histamine-2 receptor antagonists are therapeutically used for which conditions?
A. IBS and Crohn’s disease
B. GERD, gastric ulcers, duodenal ulcers, and heartburn
C. Pancreatitis
D. Gallbladder disease
Correct Answer: B
Rationale: H2 blockers are effective for acid-related disorders.
NURS 3010 - GI PT.1 - GERD & PUD- PHARMACOLOGY MOST
TESTED QUESTIONS AND ANSWERS GRADED A+ WITH
RATIONALES
1. What is the primary pharmacologic goal in the management of GERD?
A. Eliminate gastric bacteria
B. Increase intestinal motility only
C. Inhibit gastric acid secretion and protect the gastric mucosa
D. Stimulate bile secretion
Correct Answer: C
Rationale: GERD therapy focuses on decreasing acid exposure, improving gastric
emptying, and protecting the stomach lining.
2. Which medication classes inhibit gastric acid secretion?
A. Antacids and antibiotics
B. Prokinetics and mucosal protectants
C. Histamine-2 receptor antagonists and proton pump inhibitors (PPIs)
D. NSAIDs and corticosteroids
Correct Answer: C
Rationale: H2 blockers and PPIs directly suppress gastric acid production.
3. Which medications increase gastric emptying?
A. Antacids
B. PPIs
C. Prokinetic medications
D. Antibiotics
Correct Answer: C
Rationale: Prokinetics enhance GI motility and speed gastric emptying.
,ESTUDYR
4. Which medications protect the lining of the stomach?
A. PPIs only
B. Antibiotics
C. Antacids and mucosal protectants
D. Prokinetics
Correct Answer: C
Rationale: These agents neutralize acid or physically coat the gastric mucosa.
5. Which therapies are commonly used in peptic ulcer disease (PUD)?
A. Antiemetics only
B. Prokinetics only
C. PPIs, antiulcer agents, antacids, and antibiotics
D. Corticosteroids
Correct Answer: C
Rationale: PUD requires acid suppression, mucosal protection, and eradication of
H. pylori when present.
6. Which antibiotics are commonly used to treat H. pylori infection?
A. Vancomycin and ceftriaxone
B. Clarithromycin, amoxicillin, tetracycline
C. Ciprofloxacin and metronidazole only
D. Penicillin G only
Correct Answer: B
Rationale: These antibiotics are part of standard combination therapy for H.
pylori.
7. Which medications are classified as histamine-2 receptor antagonists?
A. Omeprazole and pantoprazole
B. Cimetidine and famotidine
, ESTUDYR
C. Sucralfate and misoprostol
D. Metoclopramide and ondansetron
Correct Answer: B
Rationale: Cimetidine and famotidine block H2 receptors in the stomach.
8. What is the mechanism of action of histamine-2 receptor antagonists?
A. Neutralize gastric acid
B. Destroy gastric bacteria
C. Block H2 receptors, reducing acid secretion
D. Increase prostaglandin production
Correct Answer: C
Rationale: Blocking H2 receptors decreases hydrogen ion concentration in the
stomach.
9. The therapeutic effect of H2 receptor antagonists is best described as:
A. Increased gastric motility
B. Suppressed gastric acid secretion
C. Increased bile release
D. Enhanced mucus production only
Correct Answer: B
Rationale: These medications reduce acid output and gastric acidity.
10. Histamine-2 receptor antagonists are therapeutically used for which conditions?
A. IBS and Crohn’s disease
B. GERD, gastric ulcers, duodenal ulcers, and heartburn
C. Pancreatitis
D. Gallbladder disease
Correct Answer: B
Rationale: H2 blockers are effective for acid-related disorders.
