NUR 635 ADVANCED PHARMACOLOGY MID-TERM EXAM QUESTIONS WITH CORRECT
ANSWERS LATEST UPDATE 2026
The process by which the body break down and coverts a medication into active subtance is
know as - Answers metabolism
The term NOT associated with the pharmacokinetics of a drug is - Answers Pharmacodynamics
Rationale: Pharmacokinetics can be simply described as the study of 'what the body does to the
drugs' and includes: the rate and extend to which drugs are absorbed and distributed to body
tissue; the rate and pathways by which drugs are eliminated from the body by metabolism and
excretion; and the relationship between time and plasma drug concentration. It includes the
processes of absorption, distribution, metabolism, and excretion. Pharmacodynamics is the
effect that a drug has on the body. Terms associated with pharmacodynamics include receptors
(i.e. affinity), drug potency (i.e. amount of drug required to produce a therapeutic response),
and drug response cure (i.e. effective dose, toxic dose, therapeutic index).
The elimination phase of pharmacokinetics is the time it takes for the plasma concentration of a
drug to decrease by - Answers 50%
Rationale: The elimination phase or elimination half-life is the time required for a drug to reach
half (50%) of its state in the serum.
The pharmacokinetics of a drug may be affected by - Answers Compliance by the patient.
Rationale: Factors that affect the pharmacokinetics (what the body does to the drug) of a drug
include: compliance by the patient; dosing and medication error; absorption; tissue and body
fluid; mass and volume; drug interaction; elimination and drug metabolism. Pharmacokinetics
will be variable if the drug does not reach the body or doesn't stay in the body long enough.
Pharmacodynamics (what the drug does to the body) is affected by drug receptors, genetic
factors, drug interaction, and tolerance.
In the pharmacokinetics of a drug, the rate of metabolism: - Answers varies widely among
patients.
Rationale: Metabolism is the process by which drugs are chemically changed from a lipid-
soluble from suitable for absorption and distribution to a more water-soluble form that is
, suitable for excretion. The rate of drug metabolism varies widely among patients, influenced by
genetic and environmental factors. This is the major reason for differences in the plasma
concentration of some drugs after a standard dose, leading to wide variation in drug response.
The type of study that defines the mayor metabolites concentrations in serum and other body
compartment is: - Answers Pharmacokinetics Studies
Rationale: Pharmacokinetics studies are intended to define the time course of a drug's effect
and the major metabolite concentration in the serum and other body compartment.
Pharmacokinetics is: - Answers the effect the body has on the drug
Rationale: Pharmacokinetics is the branch of pharmacology concerned withe characteristic
interactions of a drug and the body in terms of its absorption, distribution, metabolism, and
excretion.Simply put , it is what the body does to the drug. Pharmacokinetics includes the study
of: the rate and extent to which drugs are absorbed into the body and distributed to the body
tissue; the rate and pathways by which drugs are eliminated from the body by metabolism and
excretion; the relationship between time and plasma drug concentration.
Isosorbide dinitrate (Isordil) is indicated for the treatment of: - Answers Chronic Angina
Rationale: Isosorbide dinitrate (Isordil) titradose tablets are indicated for the prevention of
angina pectoris due to coronary artery disease. The onset of action of immediate-release oral
isosorbide dinitrate is not sufficiently rapid for this product to be useful in aborting an acute
angina episode. Therefore, it is not indicated int the treatment of acute angina and myocardial
infarction.
What is the maximum half-life elimination of warfarin (Coumadin)? - Answers 60 hours
Rationale: The half-life elimination of warfarin (Coumadin) is 20-60 hours. The onset of anti
coagulation action for oral warfarin (Coumadin) is 24-72 hours. Warfarin acts by binding the
synthesis of vitamin K-dependent clotting factors, including Factor II, VII, IX, and the
anticoagulant proteins C and S.
A 2 year old child has history of heart failure. To increase the force of ventricular contraction
and decrease heart rate, the most appropriate drug choice is:
ANSWERS LATEST UPDATE 2026
The process by which the body break down and coverts a medication into active subtance is
know as - Answers metabolism
The term NOT associated with the pharmacokinetics of a drug is - Answers Pharmacodynamics
Rationale: Pharmacokinetics can be simply described as the study of 'what the body does to the
drugs' and includes: the rate and extend to which drugs are absorbed and distributed to body
tissue; the rate and pathways by which drugs are eliminated from the body by metabolism and
excretion; and the relationship between time and plasma drug concentration. It includes the
processes of absorption, distribution, metabolism, and excretion. Pharmacodynamics is the
effect that a drug has on the body. Terms associated with pharmacodynamics include receptors
(i.e. affinity), drug potency (i.e. amount of drug required to produce a therapeutic response),
and drug response cure (i.e. effective dose, toxic dose, therapeutic index).
The elimination phase of pharmacokinetics is the time it takes for the plasma concentration of a
drug to decrease by - Answers 50%
Rationale: The elimination phase or elimination half-life is the time required for a drug to reach
half (50%) of its state in the serum.
The pharmacokinetics of a drug may be affected by - Answers Compliance by the patient.
Rationale: Factors that affect the pharmacokinetics (what the body does to the drug) of a drug
include: compliance by the patient; dosing and medication error; absorption; tissue and body
fluid; mass and volume; drug interaction; elimination and drug metabolism. Pharmacokinetics
will be variable if the drug does not reach the body or doesn't stay in the body long enough.
Pharmacodynamics (what the drug does to the body) is affected by drug receptors, genetic
factors, drug interaction, and tolerance.
In the pharmacokinetics of a drug, the rate of metabolism: - Answers varies widely among
patients.
Rationale: Metabolism is the process by which drugs are chemically changed from a lipid-
soluble from suitable for absorption and distribution to a more water-soluble form that is
, suitable for excretion. The rate of drug metabolism varies widely among patients, influenced by
genetic and environmental factors. This is the major reason for differences in the plasma
concentration of some drugs after a standard dose, leading to wide variation in drug response.
The type of study that defines the mayor metabolites concentrations in serum and other body
compartment is: - Answers Pharmacokinetics Studies
Rationale: Pharmacokinetics studies are intended to define the time course of a drug's effect
and the major metabolite concentration in the serum and other body compartment.
Pharmacokinetics is: - Answers the effect the body has on the drug
Rationale: Pharmacokinetics is the branch of pharmacology concerned withe characteristic
interactions of a drug and the body in terms of its absorption, distribution, metabolism, and
excretion.Simply put , it is what the body does to the drug. Pharmacokinetics includes the study
of: the rate and extent to which drugs are absorbed into the body and distributed to the body
tissue; the rate and pathways by which drugs are eliminated from the body by metabolism and
excretion; the relationship between time and plasma drug concentration.
Isosorbide dinitrate (Isordil) is indicated for the treatment of: - Answers Chronic Angina
Rationale: Isosorbide dinitrate (Isordil) titradose tablets are indicated for the prevention of
angina pectoris due to coronary artery disease. The onset of action of immediate-release oral
isosorbide dinitrate is not sufficiently rapid for this product to be useful in aborting an acute
angina episode. Therefore, it is not indicated int the treatment of acute angina and myocardial
infarction.
What is the maximum half-life elimination of warfarin (Coumadin)? - Answers 60 hours
Rationale: The half-life elimination of warfarin (Coumadin) is 20-60 hours. The onset of anti
coagulation action for oral warfarin (Coumadin) is 24-72 hours. Warfarin acts by binding the
synthesis of vitamin K-dependent clotting factors, including Factor II, VII, IX, and the
anticoagulant proteins C and S.
A 2 year old child has history of heart failure. To increase the force of ventricular contraction
and decrease heart rate, the most appropriate drug choice is:
