NAMS Certification Exam Qs & As NAMS Certification Exam Qs & As Page 1 of 26
NAMS Certification
Physiology of VMS
-thermoregulatory center altered by increase in KNDy neurons
-activation of NK3R causes hot flashes
-blockade of NK3R reduces/eliminates hot flashes
-may also be affected by: serotonin, epinephrine, and norepinephrine;
parasympathetic nerve activity
Off label rx for VMS
-SSRIs
-SNRIs
-Gabapentinoids
-Clonidine
-Oxybutynin
pg. 1
NAMS Certification Exam Qs & As NAMS Certification Exam Qs & As.pdf Page 1 of 26
,NAMS Certification Exam Qs & As NAMS Certification Exam Qs & As Page 2 of 26
Studies on Fractional Co2 Laser for GSM
-not FDA approved
-vaginal symptoms and sexual function scores increased significantly at 3
mon; noted continued improvement at 1y
Ospemifene (Osphena) indications and MOA
-for treatment of dyspareunia
-decreases vaginal pH
-improves vaginal dryness
-shifts vaginal maturational index to superficial cells
-estrogen agonist/antagonist
Ospemifene (Osphena) adverse effects
pg. 2
NAMS Certification Exam Qs & As NAMS Certification Exam Qs & As.pdf Page 2 of 26
, NAMS Certification Exam Qs & As NAMS Certification Exam Qs & As Page 3 of 26
-increase in uterine polyps
-proliferative endometrium
-slight increased risk of hemorrhagic stroke and VTE
-can increase VMS
treatment of urge incontinence
-behavioral modifications
-overactivity of the detrusor muscle
-antimuscarinics: oxybutynin
-nerve stimulation
-botox
pelvic floor muscles - superficial
-transverse perineal
-bulbospongiosus,
pg. 3
NAMS Certification Exam Qs & As NAMS Certification Exam Qs & As.pdf Page 3 of 26
NAMS Certification
Physiology of VMS
-thermoregulatory center altered by increase in KNDy neurons
-activation of NK3R causes hot flashes
-blockade of NK3R reduces/eliminates hot flashes
-may also be affected by: serotonin, epinephrine, and norepinephrine;
parasympathetic nerve activity
Off label rx for VMS
-SSRIs
-SNRIs
-Gabapentinoids
-Clonidine
-Oxybutynin
pg. 1
NAMS Certification Exam Qs & As NAMS Certification Exam Qs & As.pdf Page 1 of 26
,NAMS Certification Exam Qs & As NAMS Certification Exam Qs & As Page 2 of 26
Studies on Fractional Co2 Laser for GSM
-not FDA approved
-vaginal symptoms and sexual function scores increased significantly at 3
mon; noted continued improvement at 1y
Ospemifene (Osphena) indications and MOA
-for treatment of dyspareunia
-decreases vaginal pH
-improves vaginal dryness
-shifts vaginal maturational index to superficial cells
-estrogen agonist/antagonist
Ospemifene (Osphena) adverse effects
pg. 2
NAMS Certification Exam Qs & As NAMS Certification Exam Qs & As.pdf Page 2 of 26
, NAMS Certification Exam Qs & As NAMS Certification Exam Qs & As Page 3 of 26
-increase in uterine polyps
-proliferative endometrium
-slight increased risk of hemorrhagic stroke and VTE
-can increase VMS
treatment of urge incontinence
-behavioral modifications
-overactivity of the detrusor muscle
-antimuscarinics: oxybutynin
-nerve stimulation
-botox
pelvic floor muscles - superficial
-transverse perineal
-bulbospongiosus,
pg. 3
NAMS Certification Exam Qs & As NAMS Certification Exam Qs & As.pdf Page 3 of 26
