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MedSurg Comprehensive Final Exam 2026 – 180+ Q&A with Rationales | UTI, Renal Failure, Seizures, ICP, Neurological Disorders

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This comprehensive exam resource contains over 180 expertly crafted Medical-Surgical Nursing questions with detailed rationales, specifically tailored for 2026 final review. The content is presented in a clear Q&A format, with correct answers and clinical explanations covering a wide range of MedSurg topics tested in RN-level exams. It is ideal for both exam practice and clinical concept reinforcement. Topics include: Renal System: Acute and chronic renal failure, pyelonephritis, urolithiasis, peritoneal and hemodialysis management, urinary tract infections, and lab monitoring (BUN, creatinine, GFR). Neurological System: Myasthenia gravis, Guillain-Barré syndrome, multiple sclerosis, trigeminal neuralgia, Parkinson’s disease, seizure disorders (tonic-clonic, absence), and interventions during neuro crises (e.g., IICP, brain herniation, posturing, Glasgow Coma Scale). Infection & Safety: Antibiotic stewardship, seizure precautions, patient teaching strategies for chronic illness management. Electrolyte & Fluid Imbalances: Hypocalcemia, hyperphosphatemia, fluid restriction, and complications of fluid overload. Pharmacology: Drug administration in renal/neurological conditions, including opioid use for renal calculi, dialysis protocols, and contrast media precautions. This resource is essential for: BSN/ADN nursing students preparing for MedSurg finals NCLEX-RN candidates seeking a clinical reasoning boost Accelerated/bridge program students requiring comprehensive practice Clinical educators and preceptors providing formative assessments Each question is followed by rationale-based answers grounded in NCLEX-style logic, ensuring students grasp the “why” behind each answer choice for maximum retention and exam success. Keywords: renal failure, pyelonephritis, urolithiasis, dialysis care, urinary tract infection, myasthenia gravis, Guillain-Barre syndrome, multiple sclerosis, Parkinson’s disease, seizure precautions, increased intracranial pressure, Glasgow coma scale, tonic clonic seizure, nursing interventions, fluid overload, hypocalcemia, hyperphosphatemia, NCLEX review, MedSurg final, exam practice

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MedSurg Comprehensive Final with
Rationales 2026 Exam Questions and
Correct Answers | New Update



A client admitted for acute pyelonephritis is about to start antibiotic therapy.

Which symptom would be expected in this client?

1) Hypertension

2) Flank pain on the affected side

3) Pain that radiates toward the unaffected side

4) No tenderness with deep palpation over the

,CVA - 🧠 ANSWER ✔✔RATIONAL: 2) The client may complain of pain on

the affected side because the kidney is enlarged and might have formed an

abscess.

Hypertension is associated with chronic pyelonephritis. Pain may radiate

down the ureters or to the epigastrium. The client would have tenderness

with deep palpation over the CVA.

Discharge instructions for a client treated for acute pyelonephritis should

include which statement?

- 1. Avoid taking any dairy products.

- 2. Return for follow-up urine cultures.

- 3. Stop taking the prescribed antibiotics when the symptoms subside.

- 4. Recurrence is unlikely because you've been treated with

antibiotics. - 🧠 ANSWER ✔✔RATIONALE: 2) The client needs to return for

follow-up urine cultures because bacteriuria may be present but

asymptomatic. Intake of dairy products won't contribute to pyelonephritis.

Antibiotics need to be taken for the full course of therapy regardless of the

symptoms. Pyelonephritis typically recurs as a relapse or new infection and

frequently recurs within 2 weeks of completing therapy.

,A client is complaining of severe flank and abdominal pain. A flat plate of

the abdomen shows urolithiasis. Which intervention is important?

- 1. Strain all urine

- 2. Limit fluid intake

- 3. Enforce strict bed rest.


- 4. Encourage a high-calcium diet - 🧠 ANSWER ✔✔RATIONALE: 1) Urine

should be strained for calculi and sent to the laboratory for analysis. Fluid

intake of 3 to 4 qt. 3 to 4 L/day is encouraged to flush the urinary tract and

prevent further calculi formation. Ambulation is encouraged to help pass

the calculi through gravity. A low-calcium formation of calcium calculi.

During a health history, which statement by a client indicates a risk of renal

calculi?

- 1. "I've been drinking a lot of cola soft drinks lately."

- 2. "I've been jogging more than usual."

- 3. "I've had more stress since we adopted a child last

year."

- 4. "I'm a vegetarian and eat cheese two or three times each

day." - 🧠 ANSWER ✔✔RATIONALE: 4) Renal calculi are commonly

COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
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, composed of calcium. Diets high in calcium may predispose a person to

renal calculi. Milk and milk products are high in calcium. Cola soft drinks

don't contain ingredients that would increase the risk of renal calculi.

Jogging and increased stress aren't considered risk factors for renal calculi

formation.

A nurse is instructing a client with oxalate renal calculi. What foods should

the nurse urge the client to eliminate from his diet?

1) Citrus fruits, molasses, and dried apricots

2) Milk, cheese, and ice cream

3) Sardines, liver and kidney


4) Spinach rhubarb and asparagus - 🧠 ANSWER ✔✔RATIONALE: 4) To

reduce the formation of oxalate calculi, urge the client to avoid foods high in

oxalate, such as spinach, rhubarb, and asparagus. Other oxalate- rich

foods to avoid include tomatoes, beets, chocolate, cocoa, celery, and

parsley.

Citrus fruits, molasses, dried apricots, milk, cheese, ice cream, sardines

and organ meats do NOT produce oxalate and do NOT need to be omitted

from the client's diet.

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