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PHARM HESI Exam | Pharmacology Nursing Study Guide

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Prepare for the PHARM HESI Exam with this study guide. Includes pharmacology concepts, practice questions, and detailed answers to help nursing students master medications, dosages, and patient care principles for HESI success.

Institution
PHARM HESI
Course
PHARM HESI

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PHARM HESI EXAM PHARM HESI EXAM Page 1 of 32




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A client with coronary artery disease who is taking digoxin (Lanoxin) receives a new
prescription for atorvastatin (Lipitor). Two weeks after initiation of the Lipitor
prescription, the nurse assesses the client. Which finding requires the most immediate
intervention?


A. Heartburn.
B. Headache.
C. Constipation.
D. Vomiting.


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D. Vomiting.




A client is taking hydromorphone (Dilaudid) PO every 4 hours at home. Following
surgery, Dilaudid IV every 4 hours PRN and butorphanol tartrate (Stadol) IV every 4
hours PRN are prescribed for pain. The client received a dose of the Dilaudid IV four
hours ago, and is again requesting pain medication. Which intervention should the
nurse implement?


A. Alternate the two medications every 4 hours PRN for pain.
B. Alternate the two medications every 2 hours PRN for pain.
C. Administer only the Dilaudid every 4 hours PRN for pain.
D. Administer only the Stadol every 4 hours PRN for pain.


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C. Administer only the Dilaudid every 4 hours PRN for pain.




The healthcare provider prescribes naproxen (Naproxen) twice daily for a client with
osteoarthritis of the hands. The client tells the nurse that the drug does not seem to
be effective after three weeks. Which is the best response for the nurse to provide?


A. The frequency of the dosing is necessary to increase the effectiveness.
B. Therapeutic blood levels of this drug are reached in 4 to 6 weeks.
C. Another type of nonsteroidal antiinflammatory drug may be indicated.
D. Systemic corticosteroids are the next drugs of choice for pain relief.


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C. Another type of nonsteroidal antiinflammatory drug may be indicated.




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A client is prescribed ampicillin sodium (Omnipen) for a sinus infection. The nurse
should instruct the client to notify the healthcare provider immediately if which
symptom occurs?


A. Rash.
B. Nausea.
C. Headache.
D. Dizziness.


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A. Rash.




A client is receiving clonidine 0.1 mg/24 hr via transdermal patch. Which assessment
finding indicates the desired effect of the medication has been achieved?


A. Absence of nausea and vomiting.
B. Change in peripheral edema from +3 to +1.
C. Denial of anginal pain and shortness of breath.
D. Blood pressure from 180/120 mmHg to 140/70 mmHg.


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D. Blood pressure from 180/120 mmHg to 140/70 mmHg.




Which action is most important for the nurse to implement prior to the administration
of the antiarrhythmic drug adenosine (Adenocard)?


A. Assess pupillary response to light.
B. Instruct the client that facial flushing may occur.


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C. Apply continuous cardiac monitoring.
D. Request that family members leave the room.


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C. Apply continuous cardiac monitoring.




A client being discharged home is prescribed an antibiotic with a dosage three times
higher than it was administered when the client was in the hospital. Which route of
administration should the nurse anticipate will be prescribed for the greatest first-pass
effect?


A. Oral.
B. Sublingual.
C. Intravenous.
D. Subcutaneous.


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A. Oral.




The nurse is reviewing admission prescriptions for a client with myxedema. The nurse
should clarify with the healthcare provider which prescription for the client?


A. Liothyronine to replace iodine.
B. Furosemid for relief of fluid retention.
C. Pentobarbital sodium for sleep.
D. Nitroglycerin for angina pain.


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PHARM HESI EXAM PHARM HESI EXAM.pdf Page 4 of 32

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Institution
PHARM HESI
Course
PHARM HESI

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Uploaded on
January 23, 2026
Number of pages
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Written in
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