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NCLEX Saunders Pharmacology Exam Questions with Rationales – A+ Graded Test Bank (Latest)

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Boost your NCLEX pharmacology prep with this verified collection of A+ graded exam questions and detailed rationales from the NCLEX Saunders Pharmacology guide. Each question is designed to mimic the current NCLEX-RN test format, covering high-yield topics such as antineoplastics, cardiac meds, antibiotics, psychotropics, endocrine drugs, and more. Perfect for nursing students and NCLEX candidates looking to reinforce medication knowledge, understand side effects, and master clinical decision-making. Fully printable PDF with clear answer keys and explanations.

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NCLEX SAUNDERS PHARMACOLOGY
CURRENTLY TESTED AND GRADED
A+ LATEST EXAM WITH RATIONALES


A female client with carcinoma of the breast is admitted to the hospital for
treatment with intravenously administered doxorubicin. The client tells the
nurse that she has been told by her friends that she is going to lose all her hair.
What is the most appropriate nursing response?



"Your friends are correct."



"You will not lose your hair."



"Hair loss may occur, but it will grow back just as it is now."



"Hair loss may occur, and it will grow back, but it may have a different color or
texture." --CORRECT ANSWER--"Hair loss may occur, and it will grow back,
but it may have a different color or texture."



Alopecia (hair loss) can occur after the administration of many antineoplastic
medications. Alopecia is reversible, but the new hair growth may have a
different color and texture. Therefore, options 1, 2, and 3 are incorrect.


Page | 1

,A client with a diagnosis of rheumatoid arthritis is taking sulindac. The primary
health care provider prescribes misoprostol for the client. The nurse explains
that this medication has been prescribed for which purpose?



To enhance the effects of the sulindac



To prepare the client for weaning off the sulindac



To prevent further development of arthritic nodules



To prevent gastric complications such as ulcer disease --CORRECT ANSWER-
-To prevent gastric complications such as ulcer disease



Sulindac is a nonsteroidal anti-inflammatory drug (NSAID). Misoprostol, a
synthetic prostaglandin E1 analogue, may be prescribed to be taken
concurrently with sulindac to prevent gastric complications such as ulcer
disease. The remaining options are incorrect.



The nurse is preparing to administer albuterol to a client. Which parameters
should the nurse assess before and during therapy?



Nausea and vomiting


Page | 2

,Headache and level of consciousness



Lung sounds and presence of dyspnea



Urine output and blood urea nitrogen level --CORRECT ANSWER--Lung
sounds and presence of dyspnea



Albuterol is an adrenergic bronchodilator. The nurse assesses respiratory
pattern, lung sounds, pulse, and blood pressure before and during therapy. The
nurse also notes the color, character, and amount of sputum.



Capecitabine has been prescribed for a client with breast cancer. The nurse
should tell the client that which blood test will be done periodically while the
client is taking this medication?



Liver function tests



Bilirubin level assay



Complete blood count (CBC)




Page | 3

, Triglyceride level determination --CORRECT ANSWER--Complete blood
count (CBC)



Capecitabine is an antimetabolite used to treat metastatic breast cancer that is
resistant to other therapy. Bone marrow depression can occur from the use of
this medication, and a CBC and blood chemistry studies should be done
periodically. Liver function tests, bilirubin level assay, and triglyceride levels
are unnecessary.




A client is prescribed imipramine once daily. The nurse determines that
additional teaching is needed on the basis of which statement by the client?



"I need to avoid alcohol while taking this medication."



"I'll take the medication in the morning before breakfast."



"I won't notice any medication effects for at least 2 weeks."



"I'll be sure to take a missed medication dose as soon as possible unless it is
almost time for the next dose." --CORRECT ANSWER--"I'll take the
medication in the morning before breakfast."



Page | 4

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