NURS 663
STUDY GUIDE 2026 EXAM
QUESTIONS AND VERIFIED SOLUTIONS
Bipolar one disorder DSM five criteria - ANSWER-Manic episode: 1+ week of a colon elevated,
expansive or irritable mood and increase energy. 3+ symptoms from B: distractibility,
indiscretion, irresponsible, grandiosity, flight of ideas, activity(Increase goal-orient), decreased
need for sleep, talkativeness or pressured speech.
Bipolar two DSM five criteria - ANSWER-Hypo mania and major depressive disorder: hypo
mania same as mania with decreased severity and duration and no functional impairment for
episode of four or more days and no psychosis
Mixed episodes (bipolar) - ANSWER-Manic and depressive symptoms time by side usually with
comorbid substance abuse increased risk of suicide and psychosis
rapid cycling - ANSWER-Four or more cycles per year no greater than a week well period
Cyclothymia DSM-V Criteria - ANSWER-Two or more years of mood cycling with dysthymia
and hypo mania decreased intensity than bipolar disorder meets criteria for hypo mania but does
not meet criteria for major depressive disorder
Dysthymia DSM five criteria - ANSWER-HE'S 2 SAD depressive symptoms lasting two or more
years that is subsydromal characterized by hopelessness decreased energy, decrease self-esteem
for two years, abnormal sleep, abnormal appetite impaired decision-making.
MAOÍ Mechanism of action generally - ANSWER-Catalyzes the deamination of monoamines
intracellularly and MAO transport Reuptake extracellular monoamines
MAO-A Mechanism of action - ANSWER-MAO-A Oxidizes serotonin norepinephrine and
epinephrine
MAO-B Mechanism of action - ANSWER-Oxidizes phenylalanine
MAO-A and MAO-B mechanism of action - ANSWER-Oxidizes dopamine non-preferentially
MAOs Neumonic -2 - ANSWER-Date with Tyra banks with wine and cheese in Maui— can
cause hypertensive crisis related to tyramine from aged food.
MAWIs= my arms weight increased= effective for atypical depression
MAOs adverse effects-6 - ANSWER-Hypertensive crisis, diet restriction, avoid meds, five week
after Prozac, two week after other antidepressants, no other medications for two weeks after
discontinuing
, MAOs diet restriction-4 compounds - ANSWER-Tyrosine, high tyramine, tryptophan,
phenylalanine
Tyrosine foods-10 - ANSWER-Aged cheese, aged wine, fava or broad bean pods, sauerkraut, soy
sauce, tap or draft beer, overripe fruit, cured meat, spoiled food
MAOs drugs to avoid- 6 - ANSWER-Antidepressants, Dextromethorphan, stimulants,
sympathomimetics, meperidine, disulfiram
MAOs side effects 11 - ANSWER-Increased weight, drowsy, dizzy, orthostatic hypotension,
tremor, headache, dry mouth, constipation, change in sexual drive, peripheral Edema, sweating
Tricyclic mechanism of action - ANSWER-Inhibit 5HT2, norepinephrine, dopamine and
reuptake slows. Amino group interferes with ASP - 98 in HSERT. Causing down regulation of
receptors.
Tricyclic side effects - ANSWER-Anticholinergic effects (dry mouth, blurred vision,
constipation, urine retention, impotence). Histamine effects (sedation, increased weight).
Adrenergic alpha receptor (postural hypotension). Direct membrane effects (decrease seizure
threshold and arrhythmias). 5HT2 receptor (increase weight and decrease anxiety).
Amitriptyline dosing/Class - ANSWER-Start at 25 to 50 mg per day, titrate 25 to 50 mg per day
per week, Max dose is 300 mg per day/TCA
Names of tricyclics 10 - ANSWER-Amitriptyline, nortriptyline, clomipramine, imipramine,
protriptyline, doxepin, amoxapine, desipramine, mapratiline, tripramine
Tricyclics are useful-2 - ANSWER-Pain, migraine
Tricyclics adverse effects-2 - ANSWER-Overdoses are cardiotoxic, high potency increases the
risk of mania
Nortriptyline mnemonic - ANSWER-No-triptyline equals less sedation and hypotension
Tricyclics mnemonic-2 - ANSWER-Think car goes over tricycle to remember that an overdose is
cardiotoxic. Do you remember mechanism think trans =serotonin and norepinephrine Chans=
Na+ and Ca+ Ans= ACH and histamine
Clomipramine mnemonic/class - ANSWER-TCA- think comipramine for obsessive compulsive
disorder
Imipramine- pneumonic and class - ANSWER-I'm peeingamine- nocturnal enuresis
Unilateral electrode in ECT indications - ANSWER-Typically first line because it has less
cognitive side effects but has less efficacy
What is ECT? - ANSWER-The use of electrical shock current delivered to the brain to induce a
seizure that treats depression. Goal is to reverse atrophy.
STUDY GUIDE 2026 EXAM
QUESTIONS AND VERIFIED SOLUTIONS
Bipolar one disorder DSM five criteria - ANSWER-Manic episode: 1+ week of a colon elevated,
expansive or irritable mood and increase energy. 3+ symptoms from B: distractibility,
indiscretion, irresponsible, grandiosity, flight of ideas, activity(Increase goal-orient), decreased
need for sleep, talkativeness or pressured speech.
Bipolar two DSM five criteria - ANSWER-Hypo mania and major depressive disorder: hypo
mania same as mania with decreased severity and duration and no functional impairment for
episode of four or more days and no psychosis
Mixed episodes (bipolar) - ANSWER-Manic and depressive symptoms time by side usually with
comorbid substance abuse increased risk of suicide and psychosis
rapid cycling - ANSWER-Four or more cycles per year no greater than a week well period
Cyclothymia DSM-V Criteria - ANSWER-Two or more years of mood cycling with dysthymia
and hypo mania decreased intensity than bipolar disorder meets criteria for hypo mania but does
not meet criteria for major depressive disorder
Dysthymia DSM five criteria - ANSWER-HE'S 2 SAD depressive symptoms lasting two or more
years that is subsydromal characterized by hopelessness decreased energy, decrease self-esteem
for two years, abnormal sleep, abnormal appetite impaired decision-making.
MAOÍ Mechanism of action generally - ANSWER-Catalyzes the deamination of monoamines
intracellularly and MAO transport Reuptake extracellular monoamines
MAO-A Mechanism of action - ANSWER-MAO-A Oxidizes serotonin norepinephrine and
epinephrine
MAO-B Mechanism of action - ANSWER-Oxidizes phenylalanine
MAO-A and MAO-B mechanism of action - ANSWER-Oxidizes dopamine non-preferentially
MAOs Neumonic -2 - ANSWER-Date with Tyra banks with wine and cheese in Maui— can
cause hypertensive crisis related to tyramine from aged food.
MAWIs= my arms weight increased= effective for atypical depression
MAOs adverse effects-6 - ANSWER-Hypertensive crisis, diet restriction, avoid meds, five week
after Prozac, two week after other antidepressants, no other medications for two weeks after
discontinuing
, MAOs diet restriction-4 compounds - ANSWER-Tyrosine, high tyramine, tryptophan,
phenylalanine
Tyrosine foods-10 - ANSWER-Aged cheese, aged wine, fava or broad bean pods, sauerkraut, soy
sauce, tap or draft beer, overripe fruit, cured meat, spoiled food
MAOs drugs to avoid- 6 - ANSWER-Antidepressants, Dextromethorphan, stimulants,
sympathomimetics, meperidine, disulfiram
MAOs side effects 11 - ANSWER-Increased weight, drowsy, dizzy, orthostatic hypotension,
tremor, headache, dry mouth, constipation, change in sexual drive, peripheral Edema, sweating
Tricyclic mechanism of action - ANSWER-Inhibit 5HT2, norepinephrine, dopamine and
reuptake slows. Amino group interferes with ASP - 98 in HSERT. Causing down regulation of
receptors.
Tricyclic side effects - ANSWER-Anticholinergic effects (dry mouth, blurred vision,
constipation, urine retention, impotence). Histamine effects (sedation, increased weight).
Adrenergic alpha receptor (postural hypotension). Direct membrane effects (decrease seizure
threshold and arrhythmias). 5HT2 receptor (increase weight and decrease anxiety).
Amitriptyline dosing/Class - ANSWER-Start at 25 to 50 mg per day, titrate 25 to 50 mg per day
per week, Max dose is 300 mg per day/TCA
Names of tricyclics 10 - ANSWER-Amitriptyline, nortriptyline, clomipramine, imipramine,
protriptyline, doxepin, amoxapine, desipramine, mapratiline, tripramine
Tricyclics are useful-2 - ANSWER-Pain, migraine
Tricyclics adverse effects-2 - ANSWER-Overdoses are cardiotoxic, high potency increases the
risk of mania
Nortriptyline mnemonic - ANSWER-No-triptyline equals less sedation and hypotension
Tricyclics mnemonic-2 - ANSWER-Think car goes over tricycle to remember that an overdose is
cardiotoxic. Do you remember mechanism think trans =serotonin and norepinephrine Chans=
Na+ and Ca+ Ans= ACH and histamine
Clomipramine mnemonic/class - ANSWER-TCA- think comipramine for obsessive compulsive
disorder
Imipramine- pneumonic and class - ANSWER-I'm peeingamine- nocturnal enuresis
Unilateral electrode in ECT indications - ANSWER-Typically first line because it has less
cognitive side effects but has less efficacy
What is ECT? - ANSWER-The use of electrical shock current delivered to the brain to induce a
seizure that treats depression. Goal is to reverse atrophy.
