Pathophysiology for the Advanced Practice
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1. What refers to the silenced gene of a gene pair. - ANSWER The
imprinted gene is the silent gene of a gene pair.
2. What is the primary reason that some older adults have impaired
inflammation and wound healing? - ANSWER The underlying chronic
illness exists.
A generalized inflammatory response seen in chronic illness depletes the
body's reserves to fight against illness.
3. Which cells are the body's primary defense against parasite invasion? -
ANSWER Eosinophils are the body's primary defense against parasites.
4. What Phagocytes bacteria? - ANSWER Macrophages work by eating or
phagocytosing bacteria.
,5. What is the first response to a foreign pathogen? - ANSWER Helper T
cells
6. Which characteristic is the most important determinant of immunogenicity
when considering the antigen? - ANSWER Immunogenicity is primarily
based on the ability to recognize something foreign.
7. How are erythrocytes destroyed when mismatched blood is administered,
causing an ABO incompatibility? - ANSWER The complement pathway is
activated in response to blood incompatibility.
8. What is the hypersensitivity reaction that causes atopic dermatitis? -
ANSWER An immediate (type I) hypersensitivity reaction causes atopic
dermatitis.
9. Which four infections are considered fungal infections? - ANSWER
Infection with a fungus is called mycosis and includes dermatophytes (e.g.,
tineas, which refers to several skin mycoses, including ringworm and
athlete's foot) and yeasts, which include candida and aspergillus.
10. When is the earliest after sexual transmission of HIV that lab results can
detect infection? - ANSWER Lab testing can detect HIV RNA 4 to 10 days
after sexual transmission, whereas HIV antibody testing may take 23 to 90
days to result in a positive test. Repeat testing may be needed to rule out a
false negative test due to testing too soon after exposure, especially if a
high likelihood of exposure is suspected.
, 11. What is a characteristic of exotoxins? - ANSWER Exotoxins are released
during bacterial growth.
12. Which dietary lifestyle choice has been associated with a decreased risk for
developing colon cancer? - ANSWER The results of decreased fat
consumption have been widely studied and have demonstrated a decreased
risk of developing colon cancer.
13. Which cancer is an individual who has worked with asbestos for over 40
years most likely to develop? - ANSWER Asbestos exposure results in an
increased risk of lung and lung lining cancer.
14. Which statement is true regarding ultraviolet (UV) light?
The degree of damage is not affected by the light's wavelength. - ANSWER UV
light causes basal cell carcinoma and squamous cell carcinoma when the UVB rays
hit DNA strands, causing thymine base pairs that are side by side to pair together,
becoming thymine dimers. These thymine dimers lead to cell death or cancer.
15. Which cancer does exercise have a convincing impact on reducing? -
ANSWER Exercise-induced myokines cause apoptosis of colon cancer
cells.
16. Low healthcare literacy is recognized as a major risk factor in blood
pressure control and has been shown to have adverse effects on health
outcomes.
true or false - ANSWER TRUE
, By providing patient education at the appropriate literacy level, improved health
outcomes may result.
17. One of the goals of the National Action Plan to Improve Health Literacy is
to incorporate research and evidence-based plans of treatment from
childhood through university-level education in a manner consistent with an
individual's literacy level.
True or false - ANSWER True
Ensuring the individual can understand all elements of a treatment plan is crucial
for understanding and compliance.
18. What is a red flag for low healthcare literacy? - ANSWER Low literacy
often leads to perceived noncompliance to medical instructions, including
medication instructions. Ensuring the patient fully understands all
instructions is critical for understanding.
19. Amniocentesis is recommended for pregnant women with certain health
histories.
Which health history would result in an amniocentesis recommendation? -
ANSWER Those who have a family history of genetic disorders
20. Studies have identified several genes that play a role in the prevention of
obesity.
What do these genes influence? - ANSWER Regulation of appetite-Research
has shown that genetic mutations may cause alterations in the regulation of
appetite.