WGU D115 Advanced Pathophysiology Objective
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1. Your body has developed an increased demand for thyroid hormones. This
will lead to ____________ of the thyroid gland.
a. atrophy
b. hypertrophy
c. dysplasia
d. metaplasia - ANSWER B
2. You palpate a gangrenous leg and note the presence of crepitus. Crepitus is
associated with which of the following?
a. wet gangrene
b. dry gangrene
c. gas gangrene
d. all of the above - ANSWER C
3. Direct cell membrane destruction may result from which of the following?
a. complement activation
b. bacterial enzymes
c. free radicals
d. all of the above - ANSWER D
,4. Which of the following is true regarding apoptosis?
a. It occurrence may be physiological or pathological.
b. It does not stimulate the inflammatory process.
c. It results in phagocytosis of the apoptotic cell.
d. all of the above. - ANSWER D
5. Insufficient blood flow to a part of the body is defined as:
a. hypoxia.
b. hypoxemia.
c. necrosis.
d. ischemia. - ANSWER D
6. A cellular change, which is often precancerous, is called:
a. hyperplasia.
b. metaplasia.
c. dysplasia.
d. hypertrophy. - ANSWER C
7. Which of the following changes is indicative of irreversible cell injury?
a. sodium influx into the cytoplasm
b. glycolysis (anaerobic metabolism)
c. detachment of ribosomes from rough endoplasmic reticulum
d. release of lysosomal enzymes - ANSWER D
8. Which of the following best describes reperfusion injury?
a. The increased blood pressure in the area of reperfusion causes
rupture of small arterioles and release of free radicals.
, b. The return of blood flow to the area results in a burst of free radical
production from neutrophils that accumulated in the area.
c. Reperfusion injury results from restoration of the function of the
sodium-potassium pump.
d. Reperfusion of the area results in apoptosis of the previously
ischemic cells. - ANSWER B
9. Which of the following best describes free radicals?
a. stable molecules not normally found in the body, but introduced
exogenously during ischemia
b. unstable molecules that are normal products of oxidative metabolism
and are removed by endogenous antioxidants
c. stable molecules that have an affinity for iron in the cytoplasm of the
cell
d. none of the above - ANSWER B
10.The usual fate of apoptotic cells is which of the following?
a. metaplastic transformation
b. calcification
c. hypertrophy
d. phagocytosis
e. neoplastic transformation - ANSWER D
11.Which of the following statements is true regarding the difference between
cell necrosis and apoptosis?
a. Apoptosis is a more rapid process.
b. Apoptosis is usually initiated by ischemia-induced cell injury.
c. Apoptosis is genetically controlled.
d. Apoptosis characteristically involves rupture of the cell membrane.
- ANSWER C
, 12.A certain disease is currently found in 1 of every 10 people in the country
and 1,000 people contract the disease yearly. The population of the country
is 4,500,000. Which of the following statements is correct?
a. The prevalence of the disease is 10% and the incidence is .02%.
b. The prevalence of the disease is .02% and the incidence is 10%.
c. Neither is correct.
d. There is insufficient data - ANSWER A
13.In relation to disease development, the term "etiology" refers to which of
the following?
a. number of people with the disease
b. cause of the disease
c. definition of the disease
d. outcome of the disease - ANSWER B
14.Which of the following is(are) true about "symptoms"?
a. objective and measurable
b. the same as "signs"
c. both of the above
d. neither of the above - ANSWER D
15.In 1992, there were 980 deaths in a Midwestern city with a population of
1,000,000. At the beginning of that year, 900 cases of AIDS existed in this
population. During the year, 250 new cases of AIDS were diagnosed, and 75
people died of the disease in 1992.
Using the data given above, what was the incidence rate (per 100,000
population) at the end of 1992 for AIDS?
Assessment Comprehensive Resource To Help You
Ace 2026-2027 Includes Frequently Tested
Questions With ELABORATED 100% Correct
COMPLETE SOLUTIONS
Guaranteed Pass First Attempt!!
Current Update!!
1. Your body has developed an increased demand for thyroid hormones. This
will lead to ____________ of the thyroid gland.
a. atrophy
b. hypertrophy
c. dysplasia
d. metaplasia - ANSWER B
2. You palpate a gangrenous leg and note the presence of crepitus. Crepitus is
associated with which of the following?
a. wet gangrene
b. dry gangrene
c. gas gangrene
d. all of the above - ANSWER C
3. Direct cell membrane destruction may result from which of the following?
a. complement activation
b. bacterial enzymes
c. free radicals
d. all of the above - ANSWER D
,4. Which of the following is true regarding apoptosis?
a. It occurrence may be physiological or pathological.
b. It does not stimulate the inflammatory process.
c. It results in phagocytosis of the apoptotic cell.
d. all of the above. - ANSWER D
5. Insufficient blood flow to a part of the body is defined as:
a. hypoxia.
b. hypoxemia.
c. necrosis.
d. ischemia. - ANSWER D
6. A cellular change, which is often precancerous, is called:
a. hyperplasia.
b. metaplasia.
c. dysplasia.
d. hypertrophy. - ANSWER C
7. Which of the following changes is indicative of irreversible cell injury?
a. sodium influx into the cytoplasm
b. glycolysis (anaerobic metabolism)
c. detachment of ribosomes from rough endoplasmic reticulum
d. release of lysosomal enzymes - ANSWER D
8. Which of the following best describes reperfusion injury?
a. The increased blood pressure in the area of reperfusion causes
rupture of small arterioles and release of free radicals.
, b. The return of blood flow to the area results in a burst of free radical
production from neutrophils that accumulated in the area.
c. Reperfusion injury results from restoration of the function of the
sodium-potassium pump.
d. Reperfusion of the area results in apoptosis of the previously
ischemic cells. - ANSWER B
9. Which of the following best describes free radicals?
a. stable molecules not normally found in the body, but introduced
exogenously during ischemia
b. unstable molecules that are normal products of oxidative metabolism
and are removed by endogenous antioxidants
c. stable molecules that have an affinity for iron in the cytoplasm of the
cell
d. none of the above - ANSWER B
10.The usual fate of apoptotic cells is which of the following?
a. metaplastic transformation
b. calcification
c. hypertrophy
d. phagocytosis
e. neoplastic transformation - ANSWER D
11.Which of the following statements is true regarding the difference between
cell necrosis and apoptosis?
a. Apoptosis is a more rapid process.
b. Apoptosis is usually initiated by ischemia-induced cell injury.
c. Apoptosis is genetically controlled.
d. Apoptosis characteristically involves rupture of the cell membrane.
- ANSWER C
, 12.A certain disease is currently found in 1 of every 10 people in the country
and 1,000 people contract the disease yearly. The population of the country
is 4,500,000. Which of the following statements is correct?
a. The prevalence of the disease is 10% and the incidence is .02%.
b. The prevalence of the disease is .02% and the incidence is 10%.
c. Neither is correct.
d. There is insufficient data - ANSWER A
13.In relation to disease development, the term "etiology" refers to which of
the following?
a. number of people with the disease
b. cause of the disease
c. definition of the disease
d. outcome of the disease - ANSWER B
14.Which of the following is(are) true about "symptoms"?
a. objective and measurable
b. the same as "signs"
c. both of the above
d. neither of the above - ANSWER D
15.In 1992, there were 980 deaths in a Midwestern city with a population of
1,000,000. At the beginning of that year, 900 cases of AIDS existed in this
population. During the year, 250 new cases of AIDS were diagnosed, and 75
people died of the disease in 1992.
Using the data given above, what was the incidence rate (per 100,000
population) at the end of 1992 for AIDS?
