NURS 546 EXAM 2 TEST BANK 2026
UPDATED QUESTIONS AND ANSWERS
GRADED A+
⩥ Tolerance. Answer: With repeated ingestion of a drug, the drug shows
decreased effect. Increasing doses are required to achieve the effects
noted with the original administration.
⩥ Dependence. Answer: State of adaptation produced with repeated
administration of certain drugs so that physical symptoms occur when
the drug is discontinued abruptly.
⩥ Addiction. Answer: A change in behavior caused by biochemical
changes in the brain after continued substance use characterized by
preoccupation with and repeated use of a substance despite negative
outcomes
⩥ Withdrawal. Answer: Physiological and psychological reactions that
occur when the use of a substance is stopped abruptly
⩥ Intoxication. Answer: Condition following the ingestion of a
substance resulting in changes in level of consciousness, cognition,
perception, judgment, and behavior.
,⩥ SAMHSA (2022a) identified the goals of MAT to include. Answer: ·
improved survival
· improved treatment retention
· decreased illegal activity
· increased quality of life
· improved birth outcomes in people who use substances while pregnant
· reduced HIV and Hepatitis B & C infections
⩥ OCD/Impulsive Control Disorders. Answer: Studies indicate
dopaminergic activity in the activation of the right ventral striatum in
response to images of food in individuals with binge-eating disorders.
⩥ OCD/Impulsive Control Disorders. Answer: Pharmacologic
management is often used in combination with psychotherapy to address
eating disorders
⩥ Obesity. Answer: -Phentermine or phentermine/topiramate
-Bupropion or bupropion/naltrexone
-Lorcaserin
-Zonisamide
⩥ Anorexia. Answer: -Olanzapine
,-Avoid bupropion in individuals with anorexia nervosa and bulimia
nervosa as bupropion lowers the seizure threshold in these individuals
putting them at significantly increased risk for new-onset seizures
⩥ Bulimia. Answer: -High Dose Fluoxetine
-Avoid bupropion in individuals with anorexia nervosa and bulimia
nervosa as bupropion lowers the seizure threshold in these individuals
putting them at significantly increased risk for new-onset seizures
⩥ Binge Eating Disorder. Answer: -Topiramate
-Bupropion
-Lisdexamfetamine
⩥ SCENARIO: Bernita is a 64-year-old who has been using heroin for 6
years. She is currently unemployed and lives with her daughter in the
city center. She does not have health insurance. Answer: MAT:
Methadone
⩥ SCENARIO: Antoine is a 34-year-old who has been abusing
prescription oxycodone. He is employed but is on probation at work for
increased absenteeism. He desires MAT but is concerned about his
roommates stealing his medication to get high. Answer: MAT:
Buprenorphine plus naloxone (Suboxone)
, -Suboxone is a good option for a client who may not be able to leave
work for medication dosing, as it does not need to be taken under direct
observation.
-If one tries to administer the buprenorphine/naloxone formulation
intravenously, naloxone will prevent any rewarding effects from
buprenorphine, making this drug a less desirable street drug
⩥ Lisa is a 29-year-old who admits to using "pills, heroin, and booze"
regularly. She lives in a rural area and is employed part-time. She has a
history of poor compliance with past treatments.. Answer: MAT:
Naltrexone
RATIONALE:Naltrexone blocks mu-opioid receptors, preventing
exogenous opioids from binding there and thus preventing the
pleasurable effects of opioid consumption.
This medication also reduces alcohol consumption through the
modulation of opioid systems, thereby reducing the reinforcing effects
of alcohol.
For those clients with alcohol use disorder, who have poor adherence to
a regimen, and are unable to maintain abstinence, a long-acting injection
of naltrexone (Vivitrol) administered monthly can be efficacious
⩥ Miranda is a 20-year-old who is 18 weeks pregnant and uses heroin.
She wants to get clean "for her baby.". Answer: MAT: Buprenorphine
RATIONALE:Buprenorphine is a partial opioid agonist which binds
with a strong affinity to the mu-opioid receptor, preventing exogenous
opioids from binding at the receptor site, and preventing the pleasurable
effects of opioid consumption. While either methadone or buprenorphine
UPDATED QUESTIONS AND ANSWERS
GRADED A+
⩥ Tolerance. Answer: With repeated ingestion of a drug, the drug shows
decreased effect. Increasing doses are required to achieve the effects
noted with the original administration.
⩥ Dependence. Answer: State of adaptation produced with repeated
administration of certain drugs so that physical symptoms occur when
the drug is discontinued abruptly.
⩥ Addiction. Answer: A change in behavior caused by biochemical
changes in the brain after continued substance use characterized by
preoccupation with and repeated use of a substance despite negative
outcomes
⩥ Withdrawal. Answer: Physiological and psychological reactions that
occur when the use of a substance is stopped abruptly
⩥ Intoxication. Answer: Condition following the ingestion of a
substance resulting in changes in level of consciousness, cognition,
perception, judgment, and behavior.
,⩥ SAMHSA (2022a) identified the goals of MAT to include. Answer: ·
improved survival
· improved treatment retention
· decreased illegal activity
· increased quality of life
· improved birth outcomes in people who use substances while pregnant
· reduced HIV and Hepatitis B & C infections
⩥ OCD/Impulsive Control Disorders. Answer: Studies indicate
dopaminergic activity in the activation of the right ventral striatum in
response to images of food in individuals with binge-eating disorders.
⩥ OCD/Impulsive Control Disorders. Answer: Pharmacologic
management is often used in combination with psychotherapy to address
eating disorders
⩥ Obesity. Answer: -Phentermine or phentermine/topiramate
-Bupropion or bupropion/naltrexone
-Lorcaserin
-Zonisamide
⩥ Anorexia. Answer: -Olanzapine
,-Avoid bupropion in individuals with anorexia nervosa and bulimia
nervosa as bupropion lowers the seizure threshold in these individuals
putting them at significantly increased risk for new-onset seizures
⩥ Bulimia. Answer: -High Dose Fluoxetine
-Avoid bupropion in individuals with anorexia nervosa and bulimia
nervosa as bupropion lowers the seizure threshold in these individuals
putting them at significantly increased risk for new-onset seizures
⩥ Binge Eating Disorder. Answer: -Topiramate
-Bupropion
-Lisdexamfetamine
⩥ SCENARIO: Bernita is a 64-year-old who has been using heroin for 6
years. She is currently unemployed and lives with her daughter in the
city center. She does not have health insurance. Answer: MAT:
Methadone
⩥ SCENARIO: Antoine is a 34-year-old who has been abusing
prescription oxycodone. He is employed but is on probation at work for
increased absenteeism. He desires MAT but is concerned about his
roommates stealing his medication to get high. Answer: MAT:
Buprenorphine plus naloxone (Suboxone)
, -Suboxone is a good option for a client who may not be able to leave
work for medication dosing, as it does not need to be taken under direct
observation.
-If one tries to administer the buprenorphine/naloxone formulation
intravenously, naloxone will prevent any rewarding effects from
buprenorphine, making this drug a less desirable street drug
⩥ Lisa is a 29-year-old who admits to using "pills, heroin, and booze"
regularly. She lives in a rural area and is employed part-time. She has a
history of poor compliance with past treatments.. Answer: MAT:
Naltrexone
RATIONALE:Naltrexone blocks mu-opioid receptors, preventing
exogenous opioids from binding there and thus preventing the
pleasurable effects of opioid consumption.
This medication also reduces alcohol consumption through the
modulation of opioid systems, thereby reducing the reinforcing effects
of alcohol.
For those clients with alcohol use disorder, who have poor adherence to
a regimen, and are unable to maintain abstinence, a long-acting injection
of naltrexone (Vivitrol) administered monthly can be efficacious
⩥ Miranda is a 20-year-old who is 18 weeks pregnant and uses heroin.
She wants to get clean "for her baby.". Answer: MAT: Buprenorphine
RATIONALE:Buprenorphine is a partial opioid agonist which binds
with a strong affinity to the mu-opioid receptor, preventing exogenous
opioids from binding at the receptor site, and preventing the pleasurable
effects of opioid consumption. While either methadone or buprenorphine
