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NUR 376 – Nursing Pathophysiology | Exam 1 (93 Q&As) | Immune, Cardiac, Electrolytes | Concordia College St. Paul

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This expert-verified document is a comprehensive study guide for NUR 376 – Nursing Pathophysiology, specifically prepared for Exam 1 at Concordia College St. Paul for the 2026 academic year. It includes 93 exam-focused questions and answers, structured to support rapid learning and deep understanding of critical nursing topics. The content spans multiple body systems and clinical areas, including: Immune System: Innate and adaptive immunity, HIV/AIDS progression, systemic lupus erythematosus (SLE), hypersensitivity reactions (Types I–IV), and immunosuppression. Cardiovascular Disorders: Hypertension (primary and secondary), heart failure (left- and right-sided), angina (stable and unstable), myocardial infarction, deep vein thrombosis (DVT), and chronic venous insufficiency. Electrolyte & Fluid Balance: Hypernatremia, hyponatremia, hypermagnesemia, hypomagnesemia, dehydration, hypervolemia, and their clinical manifestations. Acid-Base Imbalances: Identification and differentiation of metabolic and respiratory acidosis/alkalosis, with common causes and signs. Cellular Physiology: Mechanisms of cellular injury, adaptation, apoptosis, and systemic inflammatory responses. This resource is ideal for: Undergraduate nursing students enrolled in courses like Pathophysiology, Adult Health, Medical-Surgical Nursing, or Foundations of Nursing. Students preparing for NCLEX or institutional clinical exams. Allied health or pre-nursing students seeking in-depth knowledge of disease processes and nursing care implications. Its clear Q&A format makes it easy to review, memorize, and apply during both exams and clinical practice. Keywords: nursing pathophysiology, NUR 376, immune disorders, electrolyte imbalances, HIV, AIDS, lupus, hypersensitivity, cardiovascular system, heart failure, hypertension, myocardial infarction, deep vein thrombosis, angina, acid base balance, cell injury, inflammation, infection, fluid balance, respiratory acidosis, metabolic acidosis, NCLEX prep

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NUR 376 Exam 1 Blueprint 2026 Expert
Verified | Ace the Test



Vascular permeability - 🧠 ANSWER ✔✔1st response- inflammation

mediators (histamines & bradykinins) cause vessels to dilate & become

more permeable, enabling WBC's & platelets to site of injury


Cellular Chemotaxis - 🧠 ANSWER ✔✔body releases chemical that dispatch

WBC's & platelets


Systemic Responses - 🧠 ANSWER ✔✔FEVER*, pain, sleepiness, lethargy,

anemia, & weight loss


Titer - 🧠 ANSWER ✔✔the level of antibody within the bloodstream, usually

corresponds with to the level of exposure to the microbe

,TB, rubella, any vaccines...




Positive means you have been exposed through infection or vaccine!


HIV - 🧠 ANSWER ✔✔attacks CD4 cells- normal range 800-1200

cells/mm^3




Becomes significant when below 500, below 200= aids


E-coli - 🧠 ANSWER ✔✔bacteria are acquired by the fecal-oral route,

usually in food or contaminated

water. The bacteria live in the intestines of healthy cattle.


Immunocompetence - 🧠 ANSWER ✔✔an individual's ability to protect

oneself from infectious agents because of a strong immune system




From a young age builds immune defenses & swiftly eliminates many

microorganisms as threats of infection


immunosuppression - 🧠 ANSWER ✔✔indicates that there is a defective

immune system that is placing a person at risk for infections.

, opportunistic infection - 🧠 ANSWER ✔✔which is an infection caused by a

microorganism that flourishes because of a host's deficient immune system


hospital-acquired infection - 🧠 ANSWER ✔✔A patient infection caused by

microorganisms that originated within the clinical environment




Difficult to treat bc often caused by antibiotic-resistant bacteria


Type I immediate hypersensitivity - 🧠 ANSWER ✔✔Allergy; person

produces many IgE antibodies against a specific allergen

Occurs minutes after contact with allergen; histamine is released

Symptoms include hives, hay fever, asthma, eczema, gastric disturbances,

and anaphylactic shock (a life-threatening severe form)


Type II cytotoxic hypersensitivity - 🧠 ANSWER ✔✔Igs attack antigens on

cell surface

Antibody-mediated cell lysis results

Blood transfusion reaction is an example of a Type II hypersensitivity




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