FNP 1 LATEST 2026 CORE EXAM MANUAL QUESTIONS AND
ANSWERS MARKED A+
✔✔What are some indications that a patient has testicular cancer as opposed to a
hydrocele or epididymitis? - ✔✔Palpable mass that is painless, possible sensation of
fullness or swelling
All painless masses are treated as cancer until proven otherwise; you will do a scrotal
ultrasound
✔✔What is the diagnostic test of choice for testicular cancer? - ✔✔Scrotal ultrasound
(Refer to urologist who will look for tumor markers. do CT, and MRI)
✔✔If a patient is experiencing anal bleeding, pain/pressure in the anal area, and
swelling of anus and the NP suspects possible anal cancer, what is the next step? -
✔✔Rectal digital exam
✔✔What is Erikson's stage for middle adults? - ✔✔Generativity vs stagnation
✔✔True/False
In middle aged individuals, heart disease and cancer are a higher cause of death than
unintentional harm/accidents. - ✔✔True.
Unintentional harm/accidents are the leading cause of death in 1-44 y/o
✔✔True/False
A breast ultrasound and routine mammograms are considered screening tools for
breast cancer. - ✔✔False.
A breast ultrasound is considered a diagnostic test for breast cancer and is not used for
routine screening. Mammograms can be used for screening and as diagnostic testing
for breast cancer.
✔✔True/False
Calcium in your diet does not cause calcium deposits (calcifications) in the breast. -
✔✔True.
✔✔What is the current recommendation for receiving mammograms for breast cancer
screenings in women aged 40-74? - ✔✔Every other year (Biennially)
✔✔What are a couple of calculators/tools that can be used to determine the risk of
breast cancer for a patient? - ✔✔Gail model
Claus model
(> or equal to 20%, patient is at high risk for breast cancer)
✔✔What is the USPSTF recommendation for colon cancer screening? -
✔✔Recommended at grade B for 40-49 y/o, recommended at grade A for 50-75 y/o
,✔✔What are some options for screening for colorectal cancer if patients will not
complete a colonoscopy (golden standard) or other methods requiring bowel prep? -
✔✔Guaiac-Based Fecal Occult Blood Test (gFOBT)-(yearly; less reliable)
Fecal Immunochemical test (FIT)-(yearly; 79% accurate)
Stool DNA w/ FIT test (Cologuard)- (every 3 years)
(Flexible sigmoidoscopy, CT colonography require bowel prep)
✔✔How often should a patient with average risk have a colonoscopy repeated? -
✔✔Every 10 years
✔✔If a patient has a first-degree relative who was diagnosed with colorectal cancer,
what is the rule of thumb for beginning colorectal screening/colonoscopies for this
patient? - ✔✔Start at age 40 OR 10 years before the age the relative was diagnosed,
whichever comes first.
Patient will likely receive colonoscopies every 5 years instead of 10 or more frequently if
additional risk factors are present
✔✔Ralph is a 25-year-old with a negative past medical history, no risk factors, and a
negative family history for colorectal cancer. When should you begin colorectal
screening for Ralph? - ✔✔45 y/o
✔✔Lucy's father was diagnosed with colon cancer at age 54 and the NP is trying to
determine when to begin screening Lucy for colorectal cancer. At what age should Lucy
begin receiving colonoscopies? What if her father was diagnosed at age 45? - ✔✔Start
at 40 years old
Start at 35 years old
✔✔What is roughly the average age of onset of menopause? - ✔✔51
(permanent cessation of menses for 12 consecutive months)
✔✔What is a hallmark symptom of menopause? - ✔✔Hot flashes
75% of women will experience
HRT is gold standard tx
✔✔True/False
For symptomatic women with an intact uterus, the use of progesterone or tissue-
selective estrogen complex (TSEC) products should be used to protect against
endometrial neoplasia. - ✔✔True.
✔✔True/False
In absence of contraindications, in women younger than 60 y/o, or within 10 years of
menopause onset, systemic hormone therapy is an appropriate therapy to protect
against bone loss. - ✔✔True.
, ✔✔Which of the following can be described as an increase in total number of stromal
and epithelial cells within the prostate gland that causes enlargement?
A. Testicular cancer
B. Prostate cancer
C. Benign prostatic hyperplasia
D. Orchitits - ✔✔C. Benign prostatic hyperplasia
✔✔What are the pharmacological treatments for benign prostatic hyperplasia? -
✔✔First line= alpha blockers (doxazosin, terazosin, tamsulosin)
5-alpha-reductase inhibitor (finasteride, dutasteride)
*BECAUSE THESE REDUCE PSA LEVEL BY 1/2 THE PSA RESULT SHOULD BE
DOUBLED FOR SCREENING FOR PROSTATE CANCER*
Cialis (if BPH with ED)
✔✔When taking ___________ medications such as ____________ and
_____________, the PSA may be reduced by 1/2 so the PSA result should be doubled
for purposes of screening for prostate cancer. - ✔✔5-alpha-reductase inhibitors
finasteride and dutasteride
✔✔A patient will be treated for _________ before prostate size is reduced with BPH. -
✔✔6-12 months
✔✔Stephen a 45 year old male presents to the clinic with complaints of malaise and
chills and noticed there was blood in his semen after ejaculating yesterday. Upon
questioning, the patient reports that he has been having urgency and frequency of
urination and some lower back pain. What does the NP suspect and what is the next
step to diagnosing the issue? What would the NP find if it is what is suspected? -
✔✔Acute prostatitis
Digital rectal exam (DO NOT MASSAGE PROSTATE), CBC, BMP, and PSA, UA with
gram stain and culture
The prostate would be tender and boggy
✔✔What is the typical treatment for acute bacterial prostatitis? - ✔✔Ciprofloxacin 500
mg PO BID for 10-14 days
Levofloxacin 500-750 mg PO BID for 10-14 days
Trimethoprim/sulfamethoxazole 160/800 BID for 10-14 days
If at risk for STI:
Ceftriaxone one time 250 mg IM
Cefixime 400 mg orally then doxycycline 100 mg BID for 10 days
✔✔If a patient has acute prostatitis, what is important to remember during the digital
rectal diagnostic exam? - ✔✔Do not massage the prostate during the exam as it may
induce iatrogenic bacteremia
ANSWERS MARKED A+
✔✔What are some indications that a patient has testicular cancer as opposed to a
hydrocele or epididymitis? - ✔✔Palpable mass that is painless, possible sensation of
fullness or swelling
All painless masses are treated as cancer until proven otherwise; you will do a scrotal
ultrasound
✔✔What is the diagnostic test of choice for testicular cancer? - ✔✔Scrotal ultrasound
(Refer to urologist who will look for tumor markers. do CT, and MRI)
✔✔If a patient is experiencing anal bleeding, pain/pressure in the anal area, and
swelling of anus and the NP suspects possible anal cancer, what is the next step? -
✔✔Rectal digital exam
✔✔What is Erikson's stage for middle adults? - ✔✔Generativity vs stagnation
✔✔True/False
In middle aged individuals, heart disease and cancer are a higher cause of death than
unintentional harm/accidents. - ✔✔True.
Unintentional harm/accidents are the leading cause of death in 1-44 y/o
✔✔True/False
A breast ultrasound and routine mammograms are considered screening tools for
breast cancer. - ✔✔False.
A breast ultrasound is considered a diagnostic test for breast cancer and is not used for
routine screening. Mammograms can be used for screening and as diagnostic testing
for breast cancer.
✔✔True/False
Calcium in your diet does not cause calcium deposits (calcifications) in the breast. -
✔✔True.
✔✔What is the current recommendation for receiving mammograms for breast cancer
screenings in women aged 40-74? - ✔✔Every other year (Biennially)
✔✔What are a couple of calculators/tools that can be used to determine the risk of
breast cancer for a patient? - ✔✔Gail model
Claus model
(> or equal to 20%, patient is at high risk for breast cancer)
✔✔What is the USPSTF recommendation for colon cancer screening? -
✔✔Recommended at grade B for 40-49 y/o, recommended at grade A for 50-75 y/o
,✔✔What are some options for screening for colorectal cancer if patients will not
complete a colonoscopy (golden standard) or other methods requiring bowel prep? -
✔✔Guaiac-Based Fecal Occult Blood Test (gFOBT)-(yearly; less reliable)
Fecal Immunochemical test (FIT)-(yearly; 79% accurate)
Stool DNA w/ FIT test (Cologuard)- (every 3 years)
(Flexible sigmoidoscopy, CT colonography require bowel prep)
✔✔How often should a patient with average risk have a colonoscopy repeated? -
✔✔Every 10 years
✔✔If a patient has a first-degree relative who was diagnosed with colorectal cancer,
what is the rule of thumb for beginning colorectal screening/colonoscopies for this
patient? - ✔✔Start at age 40 OR 10 years before the age the relative was diagnosed,
whichever comes first.
Patient will likely receive colonoscopies every 5 years instead of 10 or more frequently if
additional risk factors are present
✔✔Ralph is a 25-year-old with a negative past medical history, no risk factors, and a
negative family history for colorectal cancer. When should you begin colorectal
screening for Ralph? - ✔✔45 y/o
✔✔Lucy's father was diagnosed with colon cancer at age 54 and the NP is trying to
determine when to begin screening Lucy for colorectal cancer. At what age should Lucy
begin receiving colonoscopies? What if her father was diagnosed at age 45? - ✔✔Start
at 40 years old
Start at 35 years old
✔✔What is roughly the average age of onset of menopause? - ✔✔51
(permanent cessation of menses for 12 consecutive months)
✔✔What is a hallmark symptom of menopause? - ✔✔Hot flashes
75% of women will experience
HRT is gold standard tx
✔✔True/False
For symptomatic women with an intact uterus, the use of progesterone or tissue-
selective estrogen complex (TSEC) products should be used to protect against
endometrial neoplasia. - ✔✔True.
✔✔True/False
In absence of contraindications, in women younger than 60 y/o, or within 10 years of
menopause onset, systemic hormone therapy is an appropriate therapy to protect
against bone loss. - ✔✔True.
, ✔✔Which of the following can be described as an increase in total number of stromal
and epithelial cells within the prostate gland that causes enlargement?
A. Testicular cancer
B. Prostate cancer
C. Benign prostatic hyperplasia
D. Orchitits - ✔✔C. Benign prostatic hyperplasia
✔✔What are the pharmacological treatments for benign prostatic hyperplasia? -
✔✔First line= alpha blockers (doxazosin, terazosin, tamsulosin)
5-alpha-reductase inhibitor (finasteride, dutasteride)
*BECAUSE THESE REDUCE PSA LEVEL BY 1/2 THE PSA RESULT SHOULD BE
DOUBLED FOR SCREENING FOR PROSTATE CANCER*
Cialis (if BPH with ED)
✔✔When taking ___________ medications such as ____________ and
_____________, the PSA may be reduced by 1/2 so the PSA result should be doubled
for purposes of screening for prostate cancer. - ✔✔5-alpha-reductase inhibitors
finasteride and dutasteride
✔✔A patient will be treated for _________ before prostate size is reduced with BPH. -
✔✔6-12 months
✔✔Stephen a 45 year old male presents to the clinic with complaints of malaise and
chills and noticed there was blood in his semen after ejaculating yesterday. Upon
questioning, the patient reports that he has been having urgency and frequency of
urination and some lower back pain. What does the NP suspect and what is the next
step to diagnosing the issue? What would the NP find if it is what is suspected? -
✔✔Acute prostatitis
Digital rectal exam (DO NOT MASSAGE PROSTATE), CBC, BMP, and PSA, UA with
gram stain and culture
The prostate would be tender and boggy
✔✔What is the typical treatment for acute bacterial prostatitis? - ✔✔Ciprofloxacin 500
mg PO BID for 10-14 days
Levofloxacin 500-750 mg PO BID for 10-14 days
Trimethoprim/sulfamethoxazole 160/800 BID for 10-14 days
If at risk for STI:
Ceftriaxone one time 250 mg IM
Cefixime 400 mg orally then doxycycline 100 mg BID for 10 days
✔✔If a patient has acute prostatitis, what is important to remember during the digital
rectal diagnostic exam? - ✔✔Do not massage the prostate during the exam as it may
induce iatrogenic bacteremia
